Murcko scaffold
Barbituric acid scaffold
748 chemicals on CompoundList share this ring system.
- Rings
- 1
- Scaffold atoms
- 9
- Chemicals
- 748
- With full pages
- 67
Scaffold SMILES
O=C1CC(=O)NC(=O)N1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 748 chemicals
Amobarbital
CAS 57-43-2C11H18N2O3
Barbital
CAS 57-44-3C8H12N2O3
Butabarbital
CAS 125-40-6C10H16N2O3
Butalbital
CAS 77-26-9C11H16N2O3
Metharbital
CAS 50-11-3C9H14N2O3
Pentobarbital
CAS 76-74-4C11H18N2O3
Secobarbital
CAS 76-73-3C12H18N2O3
Allobarbital
CAS 52-43-7C10H12N2O3
Barbituric acid
CAS 67-52-7C4H4N2O3
5-Ethyl-5-(1-methylethyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
CAS 76-76-6C9H14N2O3
Aprobarbital
CAS 77-02-1C10H14N2O3
Butobarbital
CAS 77-28-1C10H16N2O3
Talbutal
CAS 115-44-6C11H16N2O3
5-Ethyl-5-hexyl-2,4,6(1H,3H,5H)-pyrimidinetrione
CAS 77-30-5C12H20N2O3
Methohexital
CAS 151-83-7C14H18N2O3
5-Nitrobarbituric acid
CAS 480-68-2C4H3N3O5
Propallylonal
CAS 545-93-7C10H13BrN2O3
5,5-Diethyl-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione
CAS 714-59-0C10H16N2O3
1,3-Dimethyl-5,5-di-2-propen-1-yl-2,4,6(1H,3H,5H)-pyrimidinetrione
CAS 722-97-4C12H16N2O3
1-Methyl-5,5-di-2-propen-1-yl-2,4,6(1H,3H,5H)-pyrimidinetrione
CAS 780-59-6C11H14N2O3
5-(2-((Aminocarbonyl)oxy)ethyl)-5-butyl-2,4,6(1H,3H,5H)-pyrimidinetrione
CAS 960-05-4C11H17N3O5
5-(2-Bromo-2-propen-1-yl)-5-(1-methylpropyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
CAS 1142-70-7C11H15BrN2O3
Barbituric acid, 5-(4-(dimethylamino)-2-butynyl)-5-ethyl-
CAS 1146-09-4C12H17N3O3
5-(2-Bromo-2-propen-1-yl)-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
CAS 1216-40-6C12H17BrN2O3
- 5-Ethylbarbituric acid2518-72-1C6H8N2O3
- Proxibarbal2537-29-3C10H14N2O4
- 5-(2-Propen-1-yl)-2,4,6(1H,3H,5H)-pyrimidinetrione2565-43-7C7H8N2O3
- 5-(1,3-Dimethylbutyl)-5-ethyl-2,4,6(1H,3H,5H)-pyrimidinetrione2964-06-9C12H20N2O3
- Barbituric acid, 5-allyl-5-(2-hydroxy-3-iodopropyl)-3258-52-4C10H13IN2O4
- Pronarcon125-55-3C11H15BrN2O3
- 5-(1,3-Dimethyl-2-butenyl)-5-ethylbarbituric acid3625-18-1C12H18N2O3
- Barbituric acid, 5-butyl-5-ethyl-1-methyl-4283-71-0C11H18N2O3
- 5-(Butan-2-yl)-6-hydroxy-3,5-dimethylpyrimidine-2,4(3H,5H)-dione4325-43-3C10H16N2O3
- 6-Hydroxy-3,5-dimethyl-5-(propan-2-yl)pyrimidine-2,4(3H,5H)-dione4336-85-0C9H14N2O3
- 1,3-Dimethyl-5-isopropylbarbituric acid7358-62-5C9H14N2O3
- 1,3-Dimethyl-5-ethylbarbituric acid7391-61-9C8H12N2O3
- 5-Butyl-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione7391-62-0C10H16N2O3
- Barbituric acid, 5-sec-butyl-1,3-dimethyl-7391-63-1C10H16N2O3
- Barbituric acid, 5,5-diethyl-1-(2-hydroxypropyl)-7548-62-1C11H18N2O4
- Barbituric acid, 1-allyl-5,5-diethyl-7548-63-2C11H16N2O3
- Barbituric acid, 5-allyl-5-(2-bromopropyl)-7548-67-6C10H13BrN2O3
- Barbituric acid, 5-allyl-5-(2-methoxypropyl)-7548-68-7C11H16N2O4
- Barbituric acid, 5-(2,3-dimethyl-2-hydroxybutyl)-5-ethyl-7548-70-1C12H20N2O4
- Barbituric acid, 1,3-diallyl-5,5-diethyl-14167-74-9C14H20N2O3
- 5-(2-Aminopropyl)-5-(2-propen-1-yl)-2,4,6(1H,3H,5H)-pyrimidinetrione14321-29-0C10H15N3O3
- Barbituric acid, 5-tert-butyl-5-ethyl-15379-32-5C10H16N2O3
- Barbituric acid, 5,5-diethyl-1-pentyl-15517-31-4C13H22N2O3
- 5,5-Dibutyl-2,4,6(1H,3H,5H)-pyrimidinetrione17013-41-1C12H20N2O3
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=c1cccc[nH]1](/scaffold/UBQKCCHYAOITMY-UHFFFAOYSA-N/structure.svg)
