Murcko scaffold
5-Azaspiro(2.4)heptane scaffold
432 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 7
- Chemicals
- 432
- With full pages
- 43
Scaffold SMILES
C1CC2(CC2)CN1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 432 chemicals
tert-Butyl (7R)-5-azaspiro(2.4)heptan-7-ylcarbamate
CAS 127199-44-4C11H20N2O2
![5-Azaspiro[2.4]heptan-1-amine chemical structure, C6H12N2, CAS 174073-88-2](/s/ILZZJZJQDKNJOH-UHFFFAOYSA-N.svg)
5-Azaspiro[2.4]heptan-1-amine
CAS 174073-88-2C6H12N2
![(R)-5-Azaspiro[2.4]heptan-7-amine dihydrochloride chemical structure, C6H14Cl2N2, CAS 328405-12-5](/s/YJMPDZLZEKRKFR-XRIGFGBMSA-N.svg)
(R)-5-Azaspiro[2.4]heptan-7-amine dihydrochloride
CAS 328405-12-5C6H14Cl2N2
![5-Azaspiro[2.4]heptan-7-amine, (7R)- chemical structure, C6H12N2, CAS 129306-11-2](/s/VBTBUCYRQSUCCE-YFKPBYRVSA-N.svg)
5-Azaspiro[2.4]heptan-7-amine, (7R)-
CAS 129306-11-2C6H12N2
![(S)-tert-Butyl 5-azaspiro[2.4]heptan-7-ylcarbamate chemical structure, C11H20N2O2, CAS 127199-45-5](/s/CGEBPOMWRHSMLI-MRVPVSSYSA-N.svg)
(S)-tert-Butyl 5-azaspiro[2.4]heptan-7-ylcarbamate
CAS 127199-45-5C11H20N2O2
![tert-Butyl 7-amino-5-azaspiro[2.4]heptane-5-carboxylate chemical structure, C11H20N2O2, CAS 1026609-83-5](/s/FNODMLLSUDSGEV-UHFFFAOYSA-N.svg)
tert-Butyl 7-amino-5-azaspiro[2.4]heptane-5-carboxylate
CAS 1026609-83-5C11H20N2O2
![5-Azaspiro[2.4]heptan-7-amine chemical structure, C6H12N2, CAS 129306-03-2](/s/VBTBUCYRQSUCCE-UHFFFAOYSA-N.svg)
5-Azaspiro[2.4]heptan-7-amine
CAS 129306-03-2C6H12N2
(7S)-5-Azaspiro(2.4)heptan-7-amine
CAS 129306-12-3C6H12N2
![7-Methyl-5-azaspiro[2.4]heptan-7-amine dihydrochloride chemical structure, C7H16Cl2N2, CAS 1044835-02-0](/s/BVLDJMARULEEGX-UHFFFAOYSA-N.svg)
7-Methyl-5-azaspiro[2.4]heptan-7-amine dihydrochloride
CAS 1044835-02-0C7H16Cl2N2
![7-Methyl-5-azaspiro[2.4]heptan-7-amine chemical structure, C7H14N2, CAS 1044904-53-1](/s/SRQMXARNYUNUBM-UHFFFAOYSA-N.svg)
7-Methyl-5-azaspiro[2.4]heptan-7-amine
CAS 1044904-53-1C7H14N2
![tert-Butyl 5-azaspiro[2.4]heptan-7-ylcarbamate chemical structure, C11H20N2O2, CAS 152513-88-7](/s/CGEBPOMWRHSMLI-UHFFFAOYSA-N.svg)
tert-Butyl 5-azaspiro[2.4]heptan-7-ylcarbamate
CAS 152513-88-7C11H20N2O2
![(S)-7-Methyl-5-azaspiro[2.4]heptan-7-amine chemical structure, C7H14N2, CAS 915360-03-1](/s/SRQMXARNYUNUBM-ZCFIWIBFSA-N.svg)
(S)-7-Methyl-5-azaspiro[2.4]heptan-7-amine
CAS 915360-03-1C7H14N2
![5-Azaspiro[2.4]heptan-7-ol chemical structure, C6H11NO, CAS 944258-72-4](/s/BHIQRZLQBMERJY-UHFFFAOYSA-N.svg)
5-Azaspiro[2.4]heptan-7-ol
CAS 944258-72-4C6H11NO
![7-Methoxy-5-azaspiro[2.4]heptane chemical structure, C7H13NO, CAS 944258-76-8](/s/JCOXLNNECBLFQE-UHFFFAOYSA-N.svg)
7-Methoxy-5-azaspiro[2.4]heptane
CAS 944258-76-8C7H13NO
tert-Butyl 5-azaspiro(2.4)heptan-1-ylcarbamate
CAS 150516-43-1C11H20N2O2
![N-Methyl-5-azaspiro[2.4]heptan-7-amine chemical structure, C7H14N2, CAS 2580238-33-9](/s/HANPDNBRRZXQEJ-UHFFFAOYSA-N.svg)
N-Methyl-5-azaspiro[2.4]heptan-7-amine
CAS 2580238-33-9C7H14N2
![5-Methyl-5-azaspiro[2.4]heptan-7-amine chemical structure, C7H14N2, CAS 1368128-52-2](/s/RFQQWGSIKZRCLS-UHFFFAOYSA-N.svg)
5-Methyl-5-azaspiro[2.4]heptan-7-amine
CAS 1368128-52-2C7H14N2
![5-Methyl-5-azaspiro[2.4]heptan-1-amine chemical structure, C7H14N2, CAS 1540564-39-3](/s/LECHHXWINAQAMT-UHFFFAOYSA-N.svg)
5-Methyl-5-azaspiro[2.4]heptan-1-amine
CAS 1540564-39-3C7H14N2
![1-{5-Methyl-5-azaspiro[2.4]heptan-7-yl}methanamine chemical structure, C8H16N2, CAS 2289190-41-4](/s/HGZYXPUBSYLQIP-UHFFFAOYSA-N.svg)
1-{5-Methyl-5-azaspiro[2.4]heptan-7-yl}methanamine
CAS 2289190-41-4C8H16N2
![5-Ethyl-5-azaspiro[2.4]heptan-7-amine chemical structure, C8H16N2, CAS 2298150-99-7](/s/NKTFKFAPPXGCTQ-UHFFFAOYSA-N.svg)
5-Ethyl-5-azaspiro[2.4]heptan-7-amine
CAS 2298150-99-7C8H16N2
![5-Azaspiro[2.4]heptan-1-amine dihydrochloride chemical structure, C6H14Cl2N2, CAS 150543-40-1](/s/OZUUGZHRALMJRF-UHFFFAOYSA-N.svg)
5-Azaspiro[2.4]heptan-1-amine dihydrochloride
CAS 150543-40-1C6H14Cl2N2
![N-Methyl-5-azaspiro[2.4]heptan-1-amine chemical structure, C7H14N2, CAS 150543-62-7](/s/ADXZQNNPGVOWLG-UHFFFAOYSA-N.svg)
N-Methyl-5-azaspiro[2.4]heptan-1-amine
CAS 150543-62-7C7H14N2
![(5-Azaspiro[2.4]heptan-1-yl)methanol chemical structure, C7H13NO, CAS 150516-41-9](/s/JLQYDCPPPJLVNV-UHFFFAOYSA-N.svg)
(5-Azaspiro[2.4]heptan-1-yl)methanol
CAS 150516-41-9C7H13NO
![5-Azaspiro[2.4]heptan-1-ol chemical structure, C6H11NO, CAS 150516-42-0](/s/OASDWVGVFKSVAY-UHFFFAOYSA-N.svg)
5-Azaspiro[2.4]heptan-1-ol
CAS 150516-42-0C6H11NO
- 1 suppliers5-[(tert-Butoxy)carbonyl]-5-azaspiro[2.4]heptane-1-carboxylic acid150543-61-6C12H19NO4
- tert-Butyl 1-((tert-butoxycarbonyl)amino)-5-azaspiro[2.4]heptane-5-carboxylate150543-46-7C16H28N2O4
- 1 suppliers5-Azaspiro[2.4]heptane-1-carboxylic acid746577-57-1C7H11NO2
- 6-Methyl-5-azaspiro[2.4]heptan-1-amine174073-86-0C7H14N2
- 5-tert-Butyl 1-ethyl 5-azaspiro[2.4]heptane-1,5-dicarboxylate150543-45-6C14H23NO4
- 4-Methyl-5-azaspiro[2.4]heptan-2-amine174073-84-8C7H14N2
- Ethyl 1-amino-5-azaspiro[2.4]heptane-5-carboxylate150543-65-0C9H16N2O2
- 1-Hydroxy-5-azaspiro[2,4]heptane hydrochloride150543-57-0C6H12ClNO
- tert-Butyl 1-(hydroxymethyl)-5-azaspiro[2.4]heptane-5-carboxylate1330766-02-3C12H21NO3
- 5-Azaspiro(2.4)heptane185-50-2C6H11N
- 5-Azaspiro[2.4]heptan-7-amine dihydrochloride400841-22-7C6H14Cl2N2
- 1 suppliers(S)-5-Azaspiro[2.4]heptan-7-amine dihydrochloride173904-24-0C6H14Cl2N2
- 4 suppliers(6S)-5-[(tert-Butoxy)carbonyl]-5-azaspiro[2.4]heptane-6-carboxylic acid1129634-44-1C12H19NO4
- 1-Amino-5-azaspiro[2.4]heptan-5-ol715651-66-4C6H12N2O
- 1-(7-Amino-5-azaspiro[2.4]heptan-5-yl)ethanone400841-20-5C8H14N2O
- (S)-1-(7-Amino-5-azaspiro[2.4]heptan-5-yl)ethanone400710-02-3C8H14N2O
- Ethyl 2-amino-6-methyl-5-azaspiro[2.4]heptane-5-carboxylate150543-79-6C10H18N2O2
- Ethyl 1-amino-4-methyl-5-azaspiro[2.4]heptane-5-carboxylate150543-77-4C10H18N2O2
- tert-Butyl (1S,3S)-5-azaspiro[2.4]heptan-1-ylcarbamate180975-59-1C11H20N2O2
- tert-Butyl (1S,3R)-5-azaspiro[2.4]heptan-1-ylcarbamate180975-57-9C11H20N2O2
- 1 suppliers1,1-Difluoro-5-azaspiro(2.4)heptane hydrochloride1215071-12-7C6H10ClF2N
- 1,1-Difluoro-5-azaspiro[2.4]heptane1215166-77-0C6H9F2N
- (1R,3S)-5-Azaspiro[2.4]heptan-1-amine150516-49-7C6H12N2
- (1R,3R)-5-Azaspiro[2.4]heptan-1-amine150516-47-5C6H12N2
Related scaffolds
Same ring framework with different atoms or bond orders
