Murcko scaffold
Spiro(2.4)heptane scaffold
162 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 7
- Chemicals
- 162
- With full pages
- 30
Scaffold SMILES
C1CCC2(C1)CC2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 162 chemicals
Spiro(2.4)heptane-1,1,2,2-tetracarbonitrile
CAS 10432-35-6C11H8N4
![Spiro[2.4]heptan-4-ol chemical structure, C7H12O, CAS 6749-50-4](/s/KRVSXRVGROMOGZ-UHFFFAOYSA-N.svg)
Spiro[2.4]heptan-4-ol
CAS 6749-50-4C7H12O
![5-(Hydroxymethyl)spiro[2.4]heptan-5-ol chemical structure, C8H14O2, CAS 109532-58-3](/s/BTEMGHFEYVOZIN-UHFFFAOYSA-N.svg)
5-(Hydroxymethyl)spiro[2.4]heptan-5-ol
CAS 109532-58-3C8H14O2
![(5R,6S)-6-Aminospiro[2.4]heptane-5-carboxylic acid chemical structure, C8H13NO2, CAS 774535-21-6](/s/VNQKBKISRGCOKY-RITPCOANSA-N.svg)
(5R,6S)-6-Aminospiro[2.4]heptane-5-carboxylic acid
CAS 774535-21-6C8H13NO2
![(4S)-4-Aminospiro[2.4]heptane-1,4-dicarboxylic acid chemical structure, C9H13NO4, CAS 371980-01-7](/s/GGWYFEZMUCMIRQ-NWAXUVLPSA-N.svg)
(4S)-4-Aminospiro[2.4]heptane-1,4-dicarboxylic acid
CAS 371980-01-7C9H13NO4
![(4R)-4-Aminospiro[2.4]heptane-1,4-dicarboxylic acid chemical structure, C9H13NO4, CAS 371980-02-8](/s/GGWYFEZMUCMIRQ-HONCAXTGSA-N.svg)
(4R)-4-Aminospiro[2.4]heptane-1,4-dicarboxylic acid
CAS 371980-02-8C9H13NO4
![N-(2-Amino-2-oxoethyl)spiro[2.4]heptane-1-carboxamide chemical structure, C10H16N2O2, CAS 680618-98-8](/s/ODRHXOVIZWNRMF-UHFFFAOYSA-N.svg)
N-(2-Amino-2-oxoethyl)spiro[2.4]heptane-1-carboxamide
CAS 680618-98-8C10H16N2O2
Spiro(2.4)heptane-1-carboxylic Acid
CAS 17202-94-7C8H12O2
![Spiro[2.4]heptane-1-carboxylic acid, 1-(aminomethyl)- chemical structure, C9H15NO2, CAS 724772-88-7](/s/OOVXSRNSUMYRGO-UHFFFAOYSA-N.svg)
Spiro[2.4]heptane-1-carboxylic acid, 1-(aminomethyl)-
CAS 724772-88-7C9H15NO2
![2-Methylspiro[2.4]heptane-1-carboxamide chemical structure, C9H15NO, CAS 680619-09-4](/s/NCIQNCAQOUNKRC-UHFFFAOYSA-N.svg)
2-Methylspiro[2.4]heptane-1-carboxamide
CAS 680619-09-4C9H15NO
![1-(Aminomethyl)-5,6-dimethylspiro[2.4]heptane-1-carboxylic acid chemical structure, C11H19NO2, CAS 724773-04-0](/s/HRLADBRXOPGTFN-UHFFFAOYSA-N.svg)
1-(Aminomethyl)-5,6-dimethylspiro[2.4]heptane-1-carboxylic acid
CAS 724773-04-0C11H19NO2
![2-Methylspiro[2.4]heptane-1-carboxylic acid chemical structure, C9H14O2, CAS 680619-08-3](/s/FDQCMJDCPIVKKF-UHFFFAOYSA-N.svg)
2-Methylspiro[2.4]heptane-1-carboxylic acid
CAS 680619-08-3C9H14O2
Methyl 1-(aminomethyl)spiro(2.4)heptane-1-carboxylate
CAS 724773-42-6C10H17NO2
![Methyl 1-cyanospiro[2.4]heptane-1-carboxylate chemical structure, C10H13NO2, CAS 724773-41-5](/s/LFMQGUQBDIIIAD-UHFFFAOYSA-N.svg)
Methyl 1-cyanospiro[2.4]heptane-1-carboxylate
CAS 724773-41-5C10H13NO2
Spiro(2.4)heptane
CAS 185-49-9C7H12
![1-Bromospiro[2.4]heptane chemical structure, C7H11Br, CAS 90001-68-6](/s/BYSNPKHMJBOSAI-UHFFFAOYSA-N.svg)
1-Bromospiro[2.4]heptane
CAS 90001-68-6C7H11Br
![4,4,5,5,6,6,7,7-Octamethylspiro[2.4]heptane chemical structure, C15H28, CAS 92406-78-5](/s/WECPIZFNVJUEGO-UHFFFAOYSA-N.svg)
4,4,5,5,6,6,7,7-Octamethylspiro[2.4]heptane
CAS 92406-78-5C15H28
![Spiro[2.4]heptan-5-ol chemical structure, C7H12O, CAS 19740-30-8](/s/SXUIBYVJKCKGSE-UHFFFAOYSA-N.svg)
Spiro[2.4]heptan-5-ol
CAS 19740-30-8C7H12O
Spiro(2.4)heptane-5-carbaldehyde
CAS 109532-60-7C8H12O
![Spiro[2.4]heptane-5-carboxylic acid chemical structure, C8H12O2, CAS 109532-61-8](/s/IIPOHIIXHDZIAO-UHFFFAOYSA-N.svg)
Spiro[2.4]heptane-5-carboxylic acid
CAS 109532-61-8C8H12O2
![Spiro[2.4]heptane-4-carbonitrile chemical structure, C8H11N, CAS 2108051-99-4](/s/OAKKFAJYENVOMB-UHFFFAOYSA-N.svg)
Spiro[2.4]heptane-4-carbonitrile
CAS 2108051-99-4C8H11N
![2-(2-Methylprop-1-en-1-yl)spiro[2.4]heptane-1-carboxylic acid chemical structure, C12H18O2, CAS 62597-12-0](/s/XBKMMVTVGXFATF-UHFFFAOYSA-N.svg)
2-(2-Methylprop-1-en-1-yl)spiro[2.4]heptane-1-carboxylic acid
CAS 62597-12-0C12H18O2
![1-(Methoxycarbonyl)spiro[2.4]heptane-1-carboxylic acid chemical structure, C10H14O4, CAS 445306-45-6](/s/SQKPUAQEPAXIOS-UHFFFAOYSA-N.svg)
1-(Methoxycarbonyl)spiro[2.4]heptane-1-carboxylic acid
CAS 445306-45-6C10H14O4
![Methyl 1-aminospiro[2.4]heptane-1-carboxylate chemical structure, C9H15NO2, CAS 669058-67-7](/s/JBDCSYPSAMOEKX-UHFFFAOYSA-N.svg)
Methyl 1-aminospiro[2.4]heptane-1-carboxylate
CAS 669058-67-7C9H15NO2
- 1-Cyanospiro[2.4]heptane-1-carboxylic acid1374509-59-7C9H11NO2
- tert-Butyl spiro[2.4]heptan-1-ylcarbamate1774896-53-5C12H21NO2
- (R)-Spiro[2.4]heptane-1-carboxylic acid1610715-21-3C8H12O2
- (S)-Spiro[2.4]heptane-1-carboxylic acid1610715-22-4C8H12O2
- Spiro[2.4]heptane-1-carbonyl chloride663618-26-6C8H11ClO
- Spiro[2.4]heptan-1-amine17202-52-7C7H13N
- 2-(2-Methylprop-1-en-1-yl)spiro[2.4]heptane-1-carbonyl chloride62597-11-9C12H17ClO
- Spiro[2.4]heptan-4-amine78294-17-4C7H13N
- Spiro[2.4]heptan-1-ylmethanamine1341334-98-2C8H15N
- Methyl 1-aminospiro[2.4]heptane-1-carboxylate hydrochloride445306-46-7C9H16ClNO2
- Ethyl 2-methylspiro[2.4]heptane-1-carboxylate110253-44-6C11H18O2
- 1-(tert-Butoxycarbonylaminomethyl)-spiro[2.4]heptane-1-carboxylic acid758697-12-0C14H23NO4
- 3-(2,2-Dibromospiro[2.4]heptan-1-yl)prop-2-enenitrile188997-86-6C10H11Br2N
- Dimethyl (1S,2S)-spiro[2.4]heptane-1,2-dicarboxylate67911-07-3C11H16O4
- Methyl (1S,2S)-2-formylspiro[2.4]heptane-1-carboxylate62222-84-8C10H14O3
- Spiro[2.4]heptan-1-ylmethanol1504251-68-6C8H14O
- 2-{Spiro[2.4]heptan-4-yl}acetic acid1368193-08-1C9H14O2
- Spiro[2.4]heptane-4-carboxylic acid1497476-15-9C8H12O2
- 2-{Spiro[2.4]heptan-4-yl}ethan-1-amine1369163-29-0C9H17N
- {Spiro[2.4]heptan-4-yl}methanamine1369166-33-5C8H15N
- 1-Methylspiro[2.4]heptane-1-carboxylic acid1522891-61-7C9H14O2
- Spiro[2.4]heptane-1-carbonitrile20778-45-4C8H11N
- Spiro[2.4]heptane-1-carbaldehyde1553910-53-4C8H12O
- 4-Aminospiro[2.4]heptane-4-carboxylic acid1545389-77-2C8H13NO2
Related scaffolds
Same ring framework with different atoms or bond orders
