Murcko scaffold
1-Oxaspiro(2.4)heptane scaffold
109 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 7
- Chemicals
- 109
- With full pages
- 2
Scaffold SMILES
C1CCC2(C1)CO2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 109 chemicals
![1-Oxaspiro[2.4]heptane-2-carboxamide chemical structure, C7H11NO2, CAS 6975-14-0](/s/FOCFGFGTHTTXIF-UHFFFAOYSA-N.svg)
1-Oxaspiro[2.4]heptane-2-carboxamide
CAS 6975-14-0C7H11NO2
![Ethyl 1-oxaspiro[2.4]heptane-2-carboxylate chemical structure, C9H14O3, CAS 6975-15-1](/s/UCHZDNBUEAXSFO-UHFFFAOYSA-N.svg)
Ethyl 1-oxaspiro[2.4]heptane-2-carboxylate
CAS 6975-15-1C9H14O3
1-Oxaspiro(2.4)heptane-2-carbonitrile
CAS 36929-35-8C7H9NO
1-Oxaspiro(2.4)heptane
CAS 185-60-4C6H10O
![1-Oxaspiro[2.4]heptane-2-carboxylic acid chemical structure, C7H10O3, CAS 5974-79-8](/s/DETMPYXZMQLKCX-UHFFFAOYSA-N.svg)
1-Oxaspiro[2.4]heptane-2-carboxylic acid
CAS 5974-79-8C7H10O3
1-Oxaspiro(2.4)heptane-2-methanol
CAS 229330-50-1C7H12O2
1-Oxaspiro(2.4)heptane, 2-(bromomethyl)-
CAS 229330-51-2C7H11BrO
![2-(Hydroxymethyl)-1-oxaspiro[2.4]heptane-2-carbonitrile chemical structure, C8H11NO2, CAS 176956-56-2](/s/YSJWVGFHUBLRIO-UHFFFAOYSA-N.svg)
2-(Hydroxymethyl)-1-oxaspiro[2.4]heptane-2-carbonitrile
CAS 176956-56-2C8H11NO2
![4,4-Dimethyl 1-oxaspiro[2.4]heptane-4,4-dicarboxylate chemical structure, C10H14O5, CAS 283176-87-4](/s/JPXJZYMMQWIDIM-UHFFFAOYSA-N.svg)
4,4-Dimethyl 1-oxaspiro[2.4]heptane-4,4-dicarboxylate
CAS 283176-87-4C10H14O5
![Methyl 2-methyl-1-oxaspiro[2.4]heptane-2-carboxylate chemical structure, C9H14O3, CAS 73039-89-1](/s/LEPHDUWNLOXRHK-UHFFFAOYSA-N.svg)
Methyl 2-methyl-1-oxaspiro[2.4]heptane-2-carboxylate
CAS 73039-89-1C9H14O3
![Trimethyl(1-oxaspiro[2.4]heptan-2-yl)silane chemical structure, C9H18OSi, CAS 63830-96-6](/s/UXUKNYDWKUZSBO-UHFFFAOYSA-N.svg)
Trimethyl(1-oxaspiro[2.4]heptan-2-yl)silane
CAS 63830-96-6C9H18OSi
![Methyl 1-oxaspiro[2.4]heptane-2-carboxylate chemical structure, C8H12O3, CAS 73039-84-6](/s/GJMSFJFIRGFSCE-UHFFFAOYSA-N.svg)
Methyl 1-oxaspiro[2.4]heptane-2-carboxylate
CAS 73039-84-6C8H12O3
![4,4,7,7-Tetramethyl-1-oxaspiro[2.4]heptane chemical structure, C10H18O, CAS 106029-84-9](/s/UHMUZGLQOOQRON-UHFFFAOYSA-N.svg)
4,4,7,7-Tetramethyl-1-oxaspiro[2.4]heptane
CAS 106029-84-9C10H18O
![2-Ethenyl-4-methyl-1-oxaspiro[2.4]heptane chemical structure, C9H14O, CAS 138352-39-3](/s/BRKUTCLODQZRKE-UHFFFAOYSA-N.svg)
2-Ethenyl-4-methyl-1-oxaspiro[2.4]heptane
CAS 138352-39-3C9H14O
![Ethyl 4-pentyl-1-oxaspiro[2.4]heptane-2-carboxylate chemical structure, C14H24O3, CAS 84812-65-7](/s/KUPPWEZAXZBBTH-UHFFFAOYSA-N.svg)
Ethyl 4-pentyl-1-oxaspiro[2.4]heptane-2-carboxylate
CAS 84812-65-7C14H24O3
![2-Methyl-1-oxaspiro[2.4]heptane-2-carboxylic acid chemical structure, C8H12O3, CAS 455935-81-6](/s/RMONOQNGVIHVRW-UHFFFAOYSA-N.svg)
2-Methyl-1-oxaspiro[2.4]heptane-2-carboxylic acid
CAS 455935-81-6C8H12O3
![2-Prop-2-enyl-1-oxaspiro[2.4]heptane chemical structure, C9H14O, CAS 119681-02-6](/s/KXLRTAMJAGHCCT-UHFFFAOYSA-N.svg)
2-Prop-2-enyl-1-oxaspiro[2.4]heptane
CAS 119681-02-6C9H14O
![5,5-Dimethyl-1-oxaspiro[2.4]heptane chemical structure, C8H14O, CAS 1539449-96-1](/s/MGDLGRDCPDEUJR-UHFFFAOYSA-N.svg)
5,5-Dimethyl-1-oxaspiro[2.4]heptane
CAS 1539449-96-1C8H14O
![5-Methyl-1-oxaspiro[2.4]heptane chemical structure, C7H12O, CAS 855398-54-8](/s/DINDSOALFYVEOR-UHFFFAOYSA-N.svg)
5-Methyl-1-oxaspiro[2.4]heptane
CAS 855398-54-8C7H12O
![4-Methyl-1-oxaspiro[2.4]heptane chemical structure, C7H12O, CAS 1488565-57-6](/s/DTCCTLXHZMMJPS-UHFFFAOYSA-N.svg)
4-Methyl-1-oxaspiro[2.4]heptane
CAS 1488565-57-6C7H12O
![Ethyl 5-ethyl-1-oxaspiro[2.4]heptane-2-carboxylate chemical structure, C11H18O3, CAS 1561453-74-4](/s/APEVDGZQZUVKEI-UHFFFAOYSA-N.svg)
Ethyl 5-ethyl-1-oxaspiro[2.4]heptane-2-carboxylate
CAS 1561453-74-4C11H18O3
![Ethyl 4-methanesulfonyl-1-oxaspiro[2.4]heptane-2-carboxylate chemical structure, C10H16O5S, CAS 1561473-39-9](/s/UEWSCFABJQTSGP-UHFFFAOYSA-N.svg)
Ethyl 4-methanesulfonyl-1-oxaspiro[2.4]heptane-2-carboxylate
CAS 1561473-39-9C10H16O5S
![Methyl 4-methyl-1-oxaspiro[2.4]heptane-2-carboxylate chemical structure, C9H14O3, CAS 73039-96-0](/s/HFJPKAMKWHRGSF-UHFFFAOYSA-N.svg)
Methyl 4-methyl-1-oxaspiro[2.4]heptane-2-carboxylate
CAS 73039-96-0C9H14O3
![Ethyl 5-methyl-1-oxaspiro[2.4]heptane-2-carboxylate chemical structure, C10H16O3, CAS 73039-99-3](/s/BLUWXBIMJVSULL-UHFFFAOYSA-N.svg)
Ethyl 5-methyl-1-oxaspiro[2.4]heptane-2-carboxylate
CAS 73039-99-3C10H16O3
- Ethyl 4-methyl-1-oxaspiro[2.4]heptane-2-carboxylate73039-97-1C10H16O3
- Methyl 5-methyl-1-oxaspiro[2.4]heptane-2-carboxylate73039-98-2C9H14O3
- Methyl 4-methanesulfonyl-1-oxaspiro[2.4]heptane-2-carboxylate1561072-71-6C9H14O5S
- Methyl 5-ethyl-1-oxaspiro[2.4]heptane-2-carboxylate1561336-67-1C10H16O3
- Methyl 2,4-dimethyl-1-oxaspiro[2.4]heptane-2-carboxylate1558973-38-8C10H16O3
- Methyl 5-ethyl-2-methyl-1-oxaspiro[2.4]heptane-2-carboxylate1559617-96-7C11H18O3
- Methyl 4-methanesulfonyl-2-methyl-1-oxaspiro[2.4]heptane-2-carboxylate1558593-32-0C10H16O5S
- Methyl 2,5-dimethyl-1-oxaspiro[2.4]heptane-2-carboxylate1558730-60-1C10H16O3
- 2-(6,7-Dimethyl-1-oxaspiro[2.4]heptan-4-yl)ethan-1-ol61612-43-9C10H18O2
- Methyl 5-ethyl-2-(propan-2-yl)-1-oxaspiro[2.4]heptane-2-carboxylate1558828-74-2C13H22O3
- Ethyl 2-ethyl-5-methyl-1-oxaspiro[2.4]heptane-2-carboxylate1559510-42-7C12H20O3
- Ethyl 2-ethyl-1-oxaspiro[2.4]heptane-2-carboxylate1507224-73-8C11H18O3
- Methyl 5-methyl-2-(propan-2-yl)-1-oxaspiro[2.4]heptane-2-carboxylate1559423-20-9C12H20O3
- Methyl 2-(propan-2-yl)-1-oxaspiro[2.4]heptane-2-carboxylate1508946-27-7C11H18O3
- Ethyl 2-ethyl-4-methyl-1-oxaspiro[2.4]heptane-2-carboxylate1559432-08-4C12H20O3
- Ethyl 2,5-diethyl-1-oxaspiro[2.4]heptane-2-carboxylate1559053-09-6C13H22O3
- Methyl 4-methyl-2-(propan-2-yl)-1-oxaspiro[2.4]heptane-2-carboxylate1559451-49-8C12H20O3
- Methyl 4,4-dimethyl-1-oxaspiro[2.4]heptane-2-carboxylate1506743-49-2C10H16O3
- Ethyl 4,4-dimethyl-1-oxaspiro[2.4]heptane-2-carboxylate1522798-62-4C11H18O3
- Methyl 2,4,4-trimethyl-1-oxaspiro[2.4]heptane-2-carboxylate1502088-23-4C11H18O3
- Ethyl 2-ethyl-4,4-dimethyl-1-oxaspiro[2.4]heptane-2-carboxylate1504545-07-6C13H22O3
- Methyl 4,4-dimethyl-2-(propan-2-yl)-1-oxaspiro[2.4]heptane-2-carboxylate1505976-81-7C13H22O3
- 4,4-Dimethyl-1-oxaspiro[2.4]heptane1510373-36-0C8H14O
- Ethyl 2-ethyl-5,5-dimethyl-1-oxaspiro[2.4]heptane-2-carboxylate1511771-42-8C13H22O3
Related scaffolds
Same ring framework with different atoms or bond orders
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