Murcko scaffold
4-Azaspiro[2.4]heptane scaffold
100 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 7
- Chemicals
- 100
- With full pages
- 15
Scaffold SMILES
C1CNC2(C1)CC2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 100 chemicals
![4-Azaspiro[2.4]heptane-5-carboxylic acid chemical structure, C7H11NO2, CAS 124032-25-3](/s/LQUHGXCDHRASRF-UHFFFAOYSA-N.svg)
4-Azaspiro[2.4]heptane-5-carboxylic acid
CAS 124032-25-3C7H11NO2
![4-Azaspiro[2.4]heptane chemical structure, C6H11N, CAS 95442-76-5](/s/JDDQECMBPWVIRU-UHFFFAOYSA-N.svg)
4-Azaspiro[2.4]heptane
CAS 95442-76-5C6H11N
![(S)-(4-Methyl-4-azaspiro[2.4]heptan-5-yl)methanol chemical structure, C8H15NO, CAS 1221443-17-9](/s/OPJQEXKBNRGOLE-ZETCQYMHSA-N.svg)
(S)-(4-Methyl-4-azaspiro[2.4]heptan-5-yl)methanol
CAS 1221443-17-9C8H15NO
![tert-Butyl 4-azaspiro[2.4]heptane-4-carboxylate chemical structure, C11H19NO2, CAS 1420294-82-1](/s/GEGJXDCDOIUIQG-UHFFFAOYSA-N.svg)
tert-Butyl 4-azaspiro[2.4]heptane-4-carboxylate
CAS 1420294-82-1C11H19NO2
![4-Azaspiro[2.4]heptan-6-ylmethanol hydrochloride chemical structure, C7H14ClNO, CAS 1956376-50-3](/s/ORINXONIWCZIJU-UHFFFAOYSA-N.svg)
4-Azaspiro[2.4]heptan-6-ylmethanol hydrochloride
CAS 1956376-50-3C7H14ClNO
![{4-Azaspiro[2.4]heptan-6-yl}methanol chemical structure, C7H13NO, CAS 1780174-58-4](/s/GFZHIKVZXCOAMR-UHFFFAOYSA-N.svg)
{4-Azaspiro[2.4]heptan-6-yl}methanol
CAS 1780174-58-4C7H13NO
![6-Methyl-4-azaspiro[2.4]heptane hydrochloride chemical structure, C7H14ClN, CAS 1823957-29-4](/s/XWTWXTQSQHRREF-UHFFFAOYSA-N.svg)
6-Methyl-4-azaspiro[2.4]heptane hydrochloride
CAS 1823957-29-4C7H14ClN
![6-Methyl-4-azaspiro[2.4]heptane chemical structure, C7H13N, CAS 1784278-11-0](/s/IULJNQJXJDCMOR-UHFFFAOYSA-N.svg)
6-Methyl-4-azaspiro[2.4]heptane
CAS 1784278-11-0C7H13N
![4-Azaspiro[2.4]heptane hydrochloride chemical structure, C6H12ClN, CAS 1414885-17-8](/s/VAYDZIKCDHPPKD-UHFFFAOYSA-N.svg)
4-Azaspiro[2.4]heptane hydrochloride
CAS 1414885-17-8C6H12ClN
![4-Azaspiro[2.4]heptane oxalate chemical structure, C8H13NO4, CAS 1980063-52-2](/s/RONUESAJAGMNIV-UHFFFAOYSA-N.svg)
4-Azaspiro[2.4]heptane oxalate
CAS 1980063-52-2C8H13NO4
![(4-Methyl-4-azaspiro[2.4]heptan-5-yl)methanol chemical structure, C8H15NO, CAS 1822857-50-0](/s/OPJQEXKBNRGOLE-UHFFFAOYSA-N.svg)
(4-Methyl-4-azaspiro[2.4]heptan-5-yl)methanol
CAS 1822857-50-0C8H15NO
![4-Azaspiro[2.4]heptan-7-ol chemical structure, C6H11NO, CAS 1556401-90-1](/s/LMDVLNHRTIBTGT-UHFFFAOYSA-N.svg)
4-Azaspiro[2.4]heptan-7-ol
CAS 1556401-90-1C6H11NO
![7,7-Difluoro-4-azaspiro[2.4]heptane chemical structure, C6H9F2N, CAS 1547146-13-3](/s/WSNMCLCXUYDXIU-UHFFFAOYSA-N.svg)
7,7-Difluoro-4-azaspiro[2.4]heptane
CAS 1547146-13-3C6H9F2N
![tert-Butyl 7-amino-4-azaspiro[2.4]heptane-4-carboxylate chemical structure, C11H20N2O2, CAS 1552636-69-7](/s/FQMOJTJPWHYUML-UHFFFAOYSA-N.svg)
tert-Butyl 7-amino-4-azaspiro[2.4]heptane-4-carboxylate
CAS 1552636-69-7C11H20N2O2
![4-Methyl-4-azaspiro[2.4]heptan-7-amine chemical structure, C7H14N2, CAS 1556044-83-7](/s/XVYYTIWEPGURTL-UHFFFAOYSA-N.svg)
4-Methyl-4-azaspiro[2.4]heptan-7-amine
CAS 1556044-83-7C7H14N2
Methyl 4-azaspiro(2.4)heptane-5-carboxylate
CAS 1779370-30-7C8H13NO2
![4-[(tert-Butoxy)carbonyl]-4-azaspiro[2.4]heptane-5-carboxylic acid chemical structure, C12H19NO4, CAS 1779469-52-1](/s/SXXIDOHJYDGJJV-UHFFFAOYSA-N.svg)
4-[(tert-Butoxy)carbonyl]-4-azaspiro[2.4]heptane-5-carboxylic acid
CAS 1779469-52-1C12H19NO4
![(S)-(4-Azaspiro[2.4]heptan-5-yl)methanol chemical structure, C7H13NO, CAS 1984825-23-1](/s/QAUMNQJMWYANBZ-UHFFFAOYSA-N.svg)
(S)-(4-Azaspiro[2.4]heptan-5-yl)methanol
CAS 1984825-23-1C7H13NO
4-Azaspiro(2.4)heptan-7-ol hydrochloride
CAS 1781039-95-9C6H12ClNO
![7-Fluoro-4-azaspiro[2.4]heptane hcl chemical structure, C6H11ClFN, CAS 1785095-42-2](/s/MZLYDQOGCLDFQZ-UHFFFAOYSA-N.svg)
7-Fluoro-4-azaspiro[2.4]heptane hcl
CAS 1785095-42-2C6H11ClFN
![7,7-Difluoro-4-azaspiro[2.4]heptane hydrochloride chemical structure, C6H10ClF2N, CAS 1781643-04-6](/s/LZYGZSQHXHNXAO-UHFFFAOYSA-N.svg)
7,7-Difluoro-4-azaspiro[2.4]heptane hydrochloride
CAS 1781643-04-6C6H10ClF2N
![4-Azaspiro[2.4]heptane trifluoroacetate chemical structure, C8H12F3NO2, CAS 1420294-80-9](/s/BMSQWGFRHCENRR-UHFFFAOYSA-N.svg)
4-Azaspiro[2.4]heptane trifluoroacetate
CAS 1420294-80-9C8H12F3NO2
![4-Azaspiro[2.4]heptane hemioxalate chemical structure, C14H24N2O4, CAS 1523571-00-7](/s/RPZBNNHPFKABOV-UHFFFAOYSA-N.svg)
4-Azaspiro[2.4]heptane hemioxalate
CAS 1523571-00-7C14H24N2O4
![4-Azaspiro[2.4]heptane-6-carboxylic acid chemical structure, C7H11NO2, CAS 1781124-30-8](/s/AZUFMQXRCBYFTB-UHFFFAOYSA-N.svg)
4-Azaspiro[2.4]heptane-6-carboxylic acid
CAS 1781124-30-8C7H11NO2
- 4-Azaspiro[2.4]heptan-6-ol hcl1784627-53-7C6H12ClNO
- Methyl 4-azaspiro[2.4]heptane-6-carboxylate1785173-54-7C8H13NO2
- tert-Butyl 6-amino-4-azaspiro[2.4]heptane-4-carboxylate1783626-63-0C11H20N2O2
- tert-Butyl (4-azaspiro[2.4]heptan-7-yl)carbamate1781190-46-2C11H20N2O2
- tert-Butyl 7-(aminomethyl)-4-azaspiro[2.4]heptane-4-carboxylate1784525-84-3C12H22N2O2
- tert-Butyl 6-(hydroxymethyl)-4-azaspiro[2.4]heptane-4-carboxylate1781130-57-1C12H21NO3
- tert-Butyl 7-(hydroxymethyl)-4-azaspiro[2.4]heptane-4-carboxylate1781110-61-9C12H21NO3
- 4-[(tert-Butoxy)carbonyl]-4-azaspiro[2.4]heptane-6-carboxylic acid1785534-09-9C12H19NO4
- 4-((tert-Butoxy)carbonyl)-4-azaspiro(2.4)heptane-7-carboxylic acid1781136-90-0C12H19NO4
- 4-Azaspiro[2.4]heptan-7-amine2680844-61-3C6H12N2
- (S)-4-Azaspiro[2.4]heptane-5-methanol Hydrochloride1984825-24-2C7H14ClNO
- (S)-4-Azaspiro[2.4]heptan-5-ylmethanolC7H13NO
- (S)-4-(tert-Butoxycarbonyl)-4-azaspiro[2.4]heptane-5-carboxylic acid1984825-25-3C12H19NO4
- tert-Butyl (S)-5-(hydroxymethyl)-4-azaspiro[2.4]heptane-4-carboxylate2007909-24-0C12H21NO3
- 2-(4-Azaspiro[2.4]heptan-4-yl)ethan-1-amine2045189-57-7C8H16N2
- (R)-(4-Azaspiro[2.4]heptan-5-yl)methanol2007909-84-2C7H13NO
- tert-Butyl (5R)-5-(hydroxymethyl)-4-azaspiro[2.4]heptane-4-carboxylate2007909-29-5C12H21NO3
- (5R)-4-[(tert-Butoxy)carbonyl]-4-azaspiro[2.4]heptane-5-carboxylic acid2007916-06-3C12H19NO4
- tert-Butyl 7-hydroxy-4-azaspiro[2.4]heptane-4-carboxylate1934960-41-4C11H19NO3
- Ethyl 4-azaspiro[2.4]heptane-6-carboxylate2092433-60-6C9H15NO2
- tert-Butyl 5-(hydroxymethyl)-4-azaspiro[2.4]heptane-4-carboxylate2090331-70-5C12H21NO3
- Ethyl 4-azaspiro[2.4]heptane-5-carboxylate2089693-55-8C9H15NO2
- tert-Butyl (R)-5-(aminomethyl)-4-azaspiro[2.4]heptane-4-carboxylate2165405-66-1C12H22N2O2
- tert-Butyl (S)-5-(aminomethyl)-4-azaspiro[2.4]heptane-4-carboxylate2166229-43-0C12H22N2O2
Related scaffolds
Same ring framework with different atoms or bond orders
