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Murcko scaffold

5-Azaspiro[2.4]heptan-4-one scaffold

33 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
8
Chemicals
33
With full pages
5
Scaffold SMILES

O=C1NCCC12CC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-Azaspiro[2.4]heptan-4-one page
Murcko scaffold O=C1NCCC12CC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 33 of 33 chemicals

5,6-Bis(1,1-dimethylethyl) (6S)-4-oxo-5-azaspiro[2.4]heptane-5,6-dicarboxylate chemical structure, C16H25NO5, CAS 201481-64-3
5,6-Bis(1,1-dimethylethyl) (6S)-4-oxo-5-azaspiro[2.4]heptane-5,6-dicarboxylate
CAS 201481-64-3C16H25NO5
7-Amino-5-azaspiro(2.4)heptan-4-one chemical structure, C6H10N2O, CAS 185421-97-0
7-Amino-5-azaspiro(2.4)heptan-4-one
CAS 185421-97-0C6H10N2O
(S)-7-Amino-5-azaspiro[2.4]heptan-4-one chemical structure, C6H10N2O, CAS 903900-37-8
(S)-7-Amino-5-azaspiro[2.4]heptan-4-one
CAS 903900-37-8C6H10N2O
5-Azaspiro[2.4]heptan-4-one chemical structure, C6H9NO, CAS 3697-70-9
5-Azaspiro[2.4]heptan-4-one
CAS 3697-70-9C6H9NO
(R)-7-Amino-5-azaspiro[2.4]heptan-4-one chemical structure, C6H10N2O, CAS 328405-11-4
(R)-7-Amino-5-azaspiro[2.4]heptan-4-one
CAS 328405-11-4C6H10N2O
7-(Methylamino)-5-azaspiro[2.4]heptan-4-one chemical structure, C7H12N2O, CAS 2648940-83-2
7-(Methylamino)-5-azaspiro[2.4]heptan-4-one
CAS 2648940-83-2C7H12N2O
5-tert-Butyl 6-ethyl (6S)-4-oxo-5-azaspiro[2.4]heptane-5,6-dicarboxylate chemical structure, C14H21NO5, CAS 158196-41-9
5-tert-Butyl 6-ethyl (6S)-4-oxo-5-azaspiro[2.4]heptane-5,6-dicarboxylate
CAS 158196-41-9C14H21NO5
tert-Butyl N-(4-oxo-5-azaspiro(2.4)heptan-7-yl)carbamate chemical structure, C11H18N2O3, CAS 903574-83-4
tert-Butyl N-(4-oxo-5-azaspiro(2.4)heptan-7-yl)carbamate
CAS 903574-83-4C11H18N2O3
tert-Butyl N-[(7S)-4-oxo-5-azaspiro[2.4]heptan-7-yl]carbamate chemical structure, C11H18N2O3, CAS 1279116-76-5
tert-Butyl N-[(7S)-4-oxo-5-azaspiro[2.4]heptan-7-yl]carbamate
CAS 1279116-76-5C11H18N2O3
7-Amino-5-methyl-5-azaspiro[2.4]heptan-4-one chemical structure, C7H12N2O, CAS 1556971-17-5
7-Amino-5-methyl-5-azaspiro[2.4]heptan-4-one
CAS 1556971-17-5C7H12N2O
4-Oxo-5-azaspiro[2.4]heptane-7-carboxylic Acid chemical structure, C7H9NO3, CAS 1426409-15-5
4-Oxo-5-azaspiro[2.4]heptane-7-carboxylic Acid
CAS 1426409-15-5C7H9NO3
(S)-6-(Hydroxymethyl)-5-azaspiro[2.4]heptan-4-one chemical structure, C7H11NO2, CAS 1817631-27-8
(S)-6-(Hydroxymethyl)-5-azaspiro[2.4]heptan-4-one
CAS 1817631-27-8C7H11NO2
7-Amino-7-methyl-5-azaspiro[2.4]heptan-4-one hydrochloride chemical structure, C7H13ClN2O, CAS 915795-01-6
7-Amino-7-methyl-5-azaspiro[2.4]heptan-4-one hydrochloride
CAS 915795-01-6C7H13ClN2O
(7S)-4-Oxo-5-azaspiro[2.4]heptane-7-carboxylic acid chemical structure, C7H9NO3, CAS 2091250-24-5
(7S)-4-Oxo-5-azaspiro[2.4]heptane-7-carboxylic acid
CAS 2091250-24-5C7H9NO3
(7R)-4-Oxo-5-azaspiro[2.4]heptane-7-carboxylic acid chemical structure, C7H9NO3, CAS 2091579-15-4
(7R)-4-Oxo-5-azaspiro[2.4]heptane-7-carboxylic acid
CAS 2091579-15-4C7H9NO3
5-Vinyl-5-azaspiro[2.4]heptan-4-one chemical structure, C8H11NO, CAS 2169339-28-8
5-Vinyl-5-azaspiro[2.4]heptan-4-one
CAS 2169339-28-8C8H11NO
(6S)-4-Oxo-5-azaspiro[2.4]heptane-6-carboxylic acid chemical structure, C7H9NO3, CAS 2102412-77-9
(6S)-4-Oxo-5-azaspiro[2.4]heptane-6-carboxylic acid
CAS 2102412-77-9C7H9NO3
5-tert-Butyl 6-methyl (6s)-4-oxo-5-azaspiro[2.4]heptane-5,6-dicarboxylate chemical structure, C13H19NO5, CAS 2102412-64-4
5-tert-Butyl 6-methyl (6s)-4-oxo-5-azaspiro[2.4]heptane-5,6-dicarboxylate
CAS 2102412-64-4C13H19NO5
Methyl 4-oxo-5-azaspiro[2.4]heptane-2-carboxylate chemical structure, C8H11NO3, CAS 1824447-48-4
Methyl 4-oxo-5-azaspiro[2.4]heptane-2-carboxylate
CAS 1824447-48-4C8H11NO3
6-Methyl-5-azaspiro[2.4]heptan-4-one chemical structure, C7H11NO, CAS 1823948-64-6
6-Methyl-5-azaspiro[2.4]heptan-4-one
CAS 1823948-64-6C7H11NO
(6R)-4-Oxo-5-azaspiro[2.4]heptane-6-carboxylic acid chemical structure, C7H9NO3, CAS 2166118-43-8
(6R)-4-Oxo-5-azaspiro[2.4]heptane-6-carboxylic acid
CAS 2166118-43-8C7H9NO3
tert-Butyl 4-oxo-5-azaspiro[2.4]heptane-5-carboxylate chemical structure, C11H17NO3, CAS 2241577-60-4
tert-Butyl 4-oxo-5-azaspiro[2.4]heptane-5-carboxylate
CAS 2241577-60-4C11H17NO3
(1S,3S,6S)-4-Oxo-5-azaspiro[2.4]heptane-1,6-dicarboxylic acid chemical structure, C8H9NO5, CAS 1868986-51-9
(1S,3S,6S)-4-Oxo-5-azaspiro[2.4]heptane-1,6-dicarboxylic acid
CAS 1868986-51-9C8H9NO5
(1S,3R,6S)-4-Oxo-5-azaspiro[2.4]heptane-1,6-dicarboxylic acid chemical structure, C8H9NO5, CAS 1868986-50-8
(1S,3R,6S)-4-Oxo-5-azaspiro[2.4]heptane-1,6-dicarboxylic acid
CAS 1868986-50-8C8H9NO5