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Murcko scaffold

5-Cyclopropyl-1,3-benzodioxole scaffold

175 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
12
Chemicals
175
With full pages
7
Scaffold SMILES

c1cc2c(cc1C1CC1)OCO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-Cyclopropyl-1,3-benzodioxole page
Murcko scaffold c1cc2c(cc1C1CC1)OCO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 175 chemicals

1-(2H-1,3-Benzodioxol-5-yl)-2-methylcyclopropan-1-amine chemical structure, C11H13NO2, CAS 1504477-10-4
1-(2H-1,3-Benzodioxol-5-yl)-2-methylcyclopropan-1-amine
CAS 1504477-10-4C11H13NO2
1-(1,3-Dioxaindan-5-yl)-2,2-dimethylcyclopropan-1-amine chemical structure, C12H15NO2, CAS 1518507-78-2
1-(1,3-Dioxaindan-5-yl)-2,2-dimethylcyclopropan-1-amine
CAS 1518507-78-2C12H15NO2
1-[1-(1,3-Dioxaindan-5-yl)cyclopropyl]ethan-1-ol chemical structure, C12H14O3, CAS 1502327-53-8
1-[1-(1,3-Dioxaindan-5-yl)cyclopropyl]ethan-1-ol
CAS 1502327-53-8C12H14O3
O-{[1-(1,3-Dioxaindan-5-yl)cyclopropyl]methyl}hydroxylamine chemical structure, C11H13NO3, CAS 1528521-97-2
O-{[1-(1,3-Dioxaindan-5-yl)cyclopropyl]methyl}hydroxylamine
CAS 1528521-97-2C11H13NO3
5-(1-Isocyanatocyclopropyl)-1,3-dioxaindane chemical structure, C11H9NO3, CAS 1504925-85-2
5-(1-Isocyanatocyclopropyl)-1,3-dioxaindane
CAS 1504925-85-2C11H9NO3
6-Cyclopropyl-1,3-dioxaindane-5-carboxylic acid chemical structure, C11H10O4, CAS 1554084-25-1
6-Cyclopropyl-1,3-dioxaindane-5-carboxylic acid
CAS 1554084-25-1C11H10O4
3-(1,3-Dioxaindan-5-yl)-2,2-dimethylcyclopropan-1-amine chemical structure, C12H15NO2, CAS 1695617-43-6
3-(1,3-Dioxaindan-5-yl)-2,2-dimethylcyclopropan-1-amine
CAS 1695617-43-6C12H15NO2
1-(6-Methoxy-1,3-dioxaindan-5-yl)cyclopropan-1-amine chemical structure, C11H13NO3, CAS 1785296-14-1
1-(6-Methoxy-1,3-dioxaindan-5-yl)cyclopropan-1-amine
CAS 1785296-14-1C11H13NO3
1-(6-Bromo-1,3-dioxaindan-5-yl)cyclopropan-1-amine chemical structure, C10H10BrNO2, CAS 1314660-05-3
1-(6-Bromo-1,3-dioxaindan-5-yl)cyclopropan-1-amine
CAS 1314660-05-3C10H10BrNO2
2,2-Difluorobenzo[d][1,3]dioxol-5-yl cyclopropanecarboxamide chemical structure, C11H9F2NO3, CAS 2071254-53-8
2,2-Difluorobenzo[d][1,3]dioxol-5-yl cyclopropanecarboxamide
CAS 2071254-53-8C11H9F2NO3
1-(2,2-Difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbaldehyde chemical structure, C11H8F2O3, CAS 2167178-27-8
1-(2,2-Difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbaldehyde
CAS 2167178-27-8C11H8F2O3
1-(1,3-Dioxaindan-5-yl)-2,2-difluorocyclopropane-1-carboxylic acid chemical structure, C11H8F2O4, CAS 2229270-72-6
1-(1,3-Dioxaindan-5-yl)-2,2-difluorocyclopropane-1-carboxylic acid
CAS 2229270-72-6C11H8F2O4
rac-(1R,2R)-2-(7-Chloro-1,3-dioxaindan-5-yl)cyclopropane-1-carboxylic acid chemical structure, C11H9ClO4, CAS 2227739-26-4
rac-(1R,2R)-2-(7-Chloro-1,3-dioxaindan-5-yl)cyclopropane-1-carboxylic acid
CAS 2227739-26-4C11H9ClO4
rac-1-[(1R,2R)-2-(1,3-Dioxaindan-5-yl)cyclopropyl]methanamine chemical structure, C11H13NO2, CAS 2227729-65-7
rac-1-[(1R,2R)-2-(1,3-Dioxaindan-5-yl)cyclopropyl]methanamine
CAS 2227729-65-7C11H13NO2
rac-(1R,3R)-3-(1,3-Dioxaindan-5-yl)-2,2-dimethylcyclopropane-1-carboxylic acid chemical structure, C13H14O4, CAS 876606-48-3
rac-(1R,3R)-3-(1,3-Dioxaindan-5-yl)-2,2-dimethylcyclopropane-1-carboxylic acid
CAS 876606-48-3C13H14O4
rac-1-[(1R,3R)-3-(1,3-Dioxaindan-5-yl)-2,2-dimethylcyclopropyl]methanamine chemical structure, C13H17NO2, CAS 2227691-78-1
rac-1-[(1R,3R)-3-(1,3-Dioxaindan-5-yl)-2,2-dimethylcyclopropyl]methanamine
CAS 2227691-78-1C13H17NO2
1-[1-(6-Bromo-1,3-dioxaindan-5-yl)cyclopropyl]methanamine chemical structure, C11H12BrNO2, CAS 1780921-07-4
1-[1-(6-Bromo-1,3-dioxaindan-5-yl)cyclopropyl]methanamine
CAS 1780921-07-4C11H12BrNO2
[1-(6-Bromo-1,3-dioxaindan-5-yl)cyclopropyl]methanol chemical structure, C11H11BrO3, CAS 1780946-64-6
[1-(6-Bromo-1,3-dioxaindan-5-yl)cyclopropyl]methanol
CAS 1780946-64-6C11H11BrO3
1-(6-Bromo-1,3-dioxaindan-5-yl)cyclopropane-1-carbaldehyde chemical structure, C11H9BrO3, CAS 1785019-39-7
1-(6-Bromo-1,3-dioxaindan-5-yl)cyclopropane-1-carbaldehyde
CAS 1785019-39-7C11H9BrO3
[1-(1,3-Dioxaindan-5-yl)-2,2-dimethylcyclopropyl]methanol chemical structure, C13H16O3, CAS 1895452-30-8
[1-(1,3-Dioxaindan-5-yl)-2,2-dimethylcyclopropyl]methanol
CAS 1895452-30-8C13H16O3
(1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropyl)methanol chemical structure, C11H10F2O3, CAS 1890666-12-2
(1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropyl)methanol
CAS 1890666-12-2C11H10F2O3
1-(6-Methoxy-1,3-dioxaindan-5-yl)cyclopropan-1-ol chemical structure, C11H12O4, CAS 1896425-86-7
1-(6-Methoxy-1,3-dioxaindan-5-yl)cyclopropan-1-ol
CAS 1896425-86-7C11H12O4
1-[1-(6-Methoxy-1,3-dioxaindan-5-yl)cyclopropyl]methanamine chemical structure, C12H15NO3, CAS 1895400-88-0
1-[1-(6-Methoxy-1,3-dioxaindan-5-yl)cyclopropyl]methanamine
CAS 1895400-88-0C12H15NO3
5-(1-Isocyanatocyclopropyl)-6-methoxy-1,3-dioxaindane chemical structure, C12H11NO4, CAS 2649082-57-3
5-(1-Isocyanatocyclopropyl)-6-methoxy-1,3-dioxaindane
CAS 2649082-57-3C12H11NO4