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Murcko scaffold

Ring system with 3 rings and 12 atoms

55 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
12
Chemicals
55
With full pages
5
Scaffold SMILES

c1cc2cn[nH]c2nc1C1CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cc2cn[nH]c2nc1C1CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 55 chemicals

6-Cyclopropyl-1-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C13H15N3O2, CAS 851288-57-8
6-Cyclopropyl-1-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 851288-57-8C13H15N3O2
6-Cyclopropyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carbohydrazide chemical structure, C12H15N5O, CAS 886496-15-7
6-Cyclopropyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carbohydrazide
CAS 886496-15-7C12H15N5O
6-Cyclopropyl-1-isopropyl-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C14H17N3O2, CAS 886502-06-3
6-Cyclopropyl-1-isopropyl-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 886502-06-3C14H17N3O2
1-Butyl-6-cyclopropyl-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C15H19N3O2, CAS 886502-91-6
1-Butyl-6-cyclopropyl-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 886502-91-6C15H19N3O2
6-Cyclopropyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C12H13N3O2, CAS 886503-63-5
6-Cyclopropyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 886503-63-5C12H13N3O2
6-Cyclopropyl-N-(2-(dimethylamino)ethyl)-1-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxamide chemical structure, C17H25N5O, CAS 878922-36-2
6-Cyclopropyl-N-(2-(dimethylamino)ethyl)-1-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxamide
CAS 878922-36-2C17H25N5O
6-Cyclopropyl-1-(2-hydroxyethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C13H15N3O3, CAS 953729-84-5
6-Cyclopropyl-1-(2-hydroxyethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 953729-84-5C13H15N3O3
6-Cyclopropyl-1-isobutyl-1H-pyrazolo[3,4-B]pyridine-4-carboxylic acid chemical structure, C14H17N3O2, CAS 954275-78-6
6-Cyclopropyl-1-isobutyl-1H-pyrazolo[3,4-B]pyridine-4-carboxylic acid
CAS 954275-78-6C14H17N3O2
6-Cyclopropyl-1-ethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C12H13N3O2, CAS 954261-91-7
6-Cyclopropyl-1-ethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 954261-91-7C12H13N3O2
1-(Butan-2-yl)-6-cyclopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C14H17N3O2, CAS 954578-37-1
1-(Butan-2-yl)-6-cyclopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 954578-37-1C14H17N3O2
Ethyl [6-cyclopropyl-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl]acetate chemical structure, C15H16F3N3O2, CAS 938002-48-3
Ethyl [6-cyclopropyl-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl]acetate
CAS 938002-48-3C15H16F3N3O2
Methyl 6-cyclopropyl-1-(2-ethoxy-2-oxoethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate chemical structure, C16H19N3O4, CAS 938018-56-5
Methyl 6-cyclopropyl-1-(2-ethoxy-2-oxoethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
CAS 938018-56-5C16H19N3O4
Methyl 6-cyclopropyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate chemical structure, C13H15N3O2, CAS 938006-47-4
Methyl 6-cyclopropyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
CAS 938006-47-4C13H15N3O2
6-Cyclopropyl-1-methyl-1H-pyrazolo(3,4-b)pyridine-4-carboxylic acid chemical structure, C11H11N3O2, CAS 937597-44-9
6-Cyclopropyl-1-methyl-1H-pyrazolo(3,4-b)pyridine-4-carboxylic acid
CAS 937597-44-9C11H11N3O2
6-Cyclopropyl-1-propyl-1H-pyrazolo(3,4-b)pyridine-4-carboxylic acid chemical structure, C13H15N3O2, CAS 937597-47-2
6-Cyclopropyl-1-propyl-1H-pyrazolo(3,4-b)pyridine-4-carboxylic acid
CAS 937597-47-2C13H15N3O2
2-(6-Cyclopropyl-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid chemical structure, C13H12F3N3O2, CAS 937605-76-0
2-(6-Cyclopropyl-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid
CAS 937605-76-0C13H12F3N3O2
2-(6-Cyclopropyl-4-(difluoromethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid chemical structure, C13H13F2N3O2, CAS 937607-09-5
2-(6-Cyclopropyl-4-(difluoromethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid
CAS 937607-09-5C13H13F2N3O2
[6-Cyclopropyl-4-(methoxycarbonyl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl]acetic acid chemical structure, C14H15N3O4, CAS 1011396-63-6
[6-Cyclopropyl-4-(methoxycarbonyl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl]acetic acid
CAS 1011396-63-6C14H15N3O4
6-Cyclopropyl-1-(2-(isopropylamino)-2-oxoethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C16H20N4O3, CAS 1011396-85-2
6-Cyclopropyl-1-(2-(isopropylamino)-2-oxoethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 1011396-85-2C16H20N4O3
5-Chloro-6-cyclopropyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C12H12ClN3O2, CAS 1018142-01-2
5-Chloro-6-cyclopropyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 1018142-01-2C12H12ClN3O2
Methyl 6-cyclopropyl-1-(2-(isopropylamino)-2-oxoethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate chemical structure, C17H22N4O3, CAS 1018051-45-0
Methyl 6-cyclopropyl-1-(2-(isopropylamino)-2-oxoethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
CAS 1018051-45-0C17H22N4O3
Methyl 1-(2-cyanoethyl)-6-cyclopropyl-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate chemical structure, C15H16N4O2, CAS 1018051-69-8
Methyl 1-(2-cyanoethyl)-6-cyclopropyl-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
CAS 1018051-69-8C15H16N4O2
Methyl 6-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate chemical structure, C14H15F2N3O2, CAS 1018142-18-1
Methyl 6-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
CAS 1018142-18-1C14H15F2N3O2
6-Cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C13H13F2N3O2, CAS 1018142-22-7
6-Cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 1018142-22-7C13H13F2N3O2