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Murcko scaffold

5-Cyclopropyl-1,3-benzodioxole scaffold

175 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
12
Chemicals
175
With full pages
7
Scaffold SMILES

c1cc2c(cc1C1CC1)OCO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-Cyclopropyl-1,3-benzodioxole page
Murcko scaffold c1cc2c(cc1C1CC1)OCO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 175 chemicals

Methyl 2-(2H-1,3-benzodioxol-5-yl)-3-methylcyclopropane-1-carboxylate chemical structure, C13H14O4, CAS 7508-38-5
Methyl 2-(2H-1,3-benzodioxol-5-yl)-3-methylcyclopropane-1-carboxylate
CAS 7508-38-5C13H14O4
2-(1,3-Benzodioxol-5-yl)cyclopropane-1-carboxylic acid chemical structure, C11H10O4, CAS 91426-77-6
2-(1,3-Benzodioxol-5-yl)cyclopropane-1-carboxylic acid
CAS 91426-77-6C11H10O4
Ethyl 2-(2H-1,3-benzodioxol-5-yl)cyclopropane-1-carboxylate chemical structure, C13H14O4, CAS 54719-15-2
Ethyl 2-(2H-1,3-benzodioxol-5-yl)cyclopropane-1-carboxylate
CAS 54719-15-2C13H14O4
1,1,2,2-Cyclopropanetetracarbonitrile, 3-(1,3-benzodioxol-5-yl)- chemical structure, C14H6N4O2, CAS 23767-75-1
1,1,2,2-Cyclopropanetetracarbonitrile, 3-(1,3-benzodioxol-5-yl)-
CAS 23767-75-1C14H6N4O2
1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarbonitrile chemical structure, C11H9NO2, CAS 33522-14-4
1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarbonitrile
CAS 33522-14-4C11H9NO2
Cyclopropanecarboxylic acid, 1-(1,3-benzodioxol-5-yl)-2,2-dichloro-, ethyl ester, (±)- chemical structure, C13H12Cl2O4, CAS 63958-13-4
Cyclopropanecarboxylic acid, 1-(1,3-benzodioxol-5-yl)-2,2-dichloro-, ethyl ester, (±)-
CAS 63958-13-4C13H12Cl2O4
6-Cyclopropyl-4,5-dimethoxy-2H-1,3-benzodioxole chemical structure, C12H14O4, CAS 94358-39-1
6-Cyclopropyl-4,5-dimethoxy-2H-1,3-benzodioxole
CAS 94358-39-1C12H14O4
4,5-Dimethoxy-6-(2-methylcyclopropyl)-2H-1,3-benzodioxole chemical structure, C13H16O4, CAS 94358-40-4
4,5-Dimethoxy-6-(2-methylcyclopropyl)-2H-1,3-benzodioxole
CAS 94358-40-4C13H16O4
1-(1,3-Dioxaindan-5-yl)cyclopropane-1-carboxylic acid chemical structure, C11H10O4, CAS 862574-89-8
1-(1,3-Dioxaindan-5-yl)cyclopropane-1-carboxylic acid
CAS 862574-89-8C11H10O4
[1-(2H-1,3-Benzodioxol-5-yl)cyclopropyl]methanol chemical structure, C11H12O3, CAS 98480-32-1
[1-(2H-1,3-Benzodioxol-5-yl)cyclopropyl]methanol
CAS 98480-32-1C11H12O3
5-(1-Ethynylcyclopropyl)-1,3-dioxaindane chemical structure, C12H10O2, CAS 100846-00-2
5-(1-Ethynylcyclopropyl)-1,3-dioxaindane
CAS 100846-00-2C12H10O2
5-Cyclopropyl-1,3-benzodioxole chemical structure, C10H10O2, CAS 29574-42-3
5-Cyclopropyl-1,3-benzodioxole
CAS 29574-42-3C10H10O2
[1-(2H-1,3-Benzodioxol-5-yl)cyclopropyl]methanamine chemical structure, C11H13NO2, CAS 221137-44-6
[1-(2H-1,3-Benzodioxol-5-yl)cyclopropyl]methanamine
CAS 221137-44-6C11H13NO2
1-(1,3-Benzodioxol-5-yl)cyclopropanecarboxaldehyde chemical structure, C11H10O3, CAS 33522-15-5
1-(1,3-Benzodioxol-5-yl)cyclopropanecarboxaldehyde
CAS 33522-15-5C11H10O3
2-(1,3-Dioxaindan-5-yl)cyclopropan-1-amine chemical structure, C10H11NO2, CAS 90921-91-8
2-(1,3-Dioxaindan-5-yl)cyclopropan-1-amine
CAS 90921-91-8C10H11NO2
rac-(1R,2R)-2-(1,3-Dioxaindan-5-yl)cyclopropane-1-carboxylic acid chemical structure, C11H10O4, CAS 7477-52-3
rac-(1R,2R)-2-(1,3-Dioxaindan-5-yl)cyclopropane-1-carboxylic acid
CAS 7477-52-3C11H10O4
rac-(1R,2S)-2-(1,3-Dioxaindan-5-yl)cyclopropan-1-amine chemical structure, C10H11NO2, CAS 73348-38-6
rac-(1R,2S)-2-(1,3-Dioxaindan-5-yl)cyclopropan-1-amine
CAS 73348-38-6C10H11NO2
rac-1-[(1R,2R)-2-(1,3-Dioxaindan-5-yl)cyclopropyl]ethan-1-one chemical structure, C12H12O3, CAS 2227884-82-2
rac-1-[(1R,2R)-2-(1,3-Dioxaindan-5-yl)cyclopropyl]ethan-1-one
CAS 2227884-82-2C12H12O3
1-(Benzo[D][1,3]dioxol-5-yl)cyclopropanamine chemical structure, C10H11NO2, CAS 1038388-99-6
1-(Benzo[D][1,3]dioxol-5-yl)cyclopropanamine
CAS 1038388-99-6C10H11NO2
2-(7-Chloro-1,3-dioxaindan-5-yl)cyclopropane-1-carboxylic acid chemical structure, C11H9ClO4, CAS 1157698-14-0
2-(7-Chloro-1,3-dioxaindan-5-yl)cyclopropane-1-carboxylic acid
CAS 1157698-14-0C11H9ClO4
2-(7-Chloro-1,3-dioxaindan-5-yl)cyclopropan-1-amine chemical structure, C10H10ClNO2, CAS 1157556-00-7
2-(7-Chloro-1,3-dioxaindan-5-yl)cyclopropan-1-amine
CAS 1157556-00-7C10H10ClNO2
1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarboxylic acid chemical structure, C11H8F2O4, CAS 862574-88-7
1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarboxylic acid
CAS 862574-88-7C11H8F2O4
1-(1,3-Dioxaindan-5-yl)-N-methylcyclopropan-1-amine chemical structure, C11H13NO2, CAS 1503467-12-6
1-(1,3-Dioxaindan-5-yl)-N-methylcyclopropan-1-amine
CAS 1503467-12-6C11H13NO2
1-(2,2-Difluorobenzo[D][1,3]dioxol-5-yl)cyclopropanecarbonitrile chemical structure, C11H7F2NO2, CAS 862574-87-6
1-(2,2-Difluorobenzo[D][1,3]dioxol-5-yl)cyclopropanecarbonitrile
CAS 862574-87-6C11H7F2NO2