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Murcko scaffold

5-Phenylbarbituric acid scaffold

177 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 15
Chemicals: 177
With full pages: 18

Scaffold SMILES

O=C1NC(=O)C(c2ccccc2)C(=O)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 5-Phenylbarbituric acid page

Murcko scaffold O=C1NC(=O)C(c2ccccc2)C(=O)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 177 chemicals

Phenobarbital chemical structure, C12H12N2O3, CAS 50-06-6

CAS 50-06-6C₁₂H₁₂N₂O₃

Mephobarbital chemical structure, C13H14N2O3, CAS 115-38-8

CAS 115-38-8C₁₃H₁₄N₂O₃

Phenallymal chemical structure, C13H12N2O3, CAS 115-43-5

CAS 115-43-5C₁₃H₁₂N₂O₃

Barbituric acid, 5-(m-chlorophenyl)-5-ethyl- chemical structure, C12H11ClN2O3, CAS 379-32-8

Barbituric acid, 5-(m-chlorophenyl)-5-ethyl-

CAS 379-32-8C₁₂H₁₁ClN₂O₃

Hydroxyphenobarbital chemical structure, C12H12N2O4, CAS 379-34-0

Hydroxyphenobarbital

CAS 379-34-0C₁₂H₁₂N₂O₄

Barbituric acid, 5-(p-chlorophenyl)-5-ethyl- chemical structure, C12H11ClN2O3, CAS 427-18-9

Barbituric acid, 5-(p-chlorophenyl)-5-ethyl-

CAS 427-18-9C₁₂H₁₁ClN₂O₃

5-Ethyl-1,3-dimethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione chemical structure, C14H16N2O3, CAS 730-66-5

5-Ethyl-1,3-dimethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione

CAS 730-66-5C₁₄H₁₆N₂O₃

5-(4-Fluorophenyl)-5-(2-propen-1-yl)-2,4,6(1H,3H,5H)-pyrimidinetrione chemical structure, C13H11FN2O3, CAS 3794-17-0

5-(4-Fluorophenyl)-5-(2-propen-1-yl)-2,4,6(1H,3H,5H)-pyrimidinetrione

CAS 3794-17-0C₁₃H₁₁FN₂O₃

Febarbamate chemical structure, C20H27N3O6, CAS 13246-02-1

CAS 13246-02-1C₂₀H₂₇N₃O₆

Barbituric acid, 5-butyl-5-phenyl- chemical structure, C14H16N2O3, CAS 13554-11-5

Barbituric acid, 5-butyl-5-phenyl-

CAS 13554-11-5C₁₄H₁₆N₂O₃

5-Ethyl-6-hydroxy-5-phenyl-3-(prop-2-en-1-yl)pyrimidine-2,4(3H,5H)-dione chemical structure, C15H16N2O3, CAS 14167-72-7

5-Ethyl-6-hydroxy-5-phenyl-3-(prop-2-en-1-yl)pyrimidine-2,4(3H,5H)-dione

CAS 14167-72-7C₁₅H₁₆N₂O₃

5-Ethyl-5-phenyl-1,3-di(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione chemical structure, C18H20N2O3, CAS 16846-63-2

5-Ethyl-5-phenyl-1,3-di(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione

CAS 16846-63-2C₁₈H₂₀N₂O₃

Dichlorophenobarbital chemical structure, C12H10Cl2N2O3, CAS 23256-01-1

Dichlorophenobarbital

CAS 23256-01-1C₁₂H₁₀Cl₂N₂O₃

Barbituric acid, 1,3-bis(acetoxymethyl)-5-ethyl-5-phenyl- chemical structure, C18H20N2O7, CAS 27506-78-1

Barbituric acid, 1,3-bis(acetoxymethyl)-5-ethyl-5-phenyl-

CAS 27506-78-1C₁₈H₂₀N₂O₇

Eterobarb chemical structure, C16H20N2O5, CAS 27511-99-5

CAS 27511-99-5C₁₆H₂₀N₂O₅

Barbituric acid, 1,3-bis(ethoxymethyl)-5-ethyl-5-phenyl- chemical structure, C18H24N2O5, CAS 27512-03-4

Barbituric acid, 1,3-bis(ethoxymethyl)-5-ethyl-5-phenyl-

CAS 27512-03-4C₁₈H₂₄N₂O₅

N-Methoxymethylphenobarbital chemical structure, C14H16N2O4, CAS 42013-65-0

N-Methoxymethylphenobarbital

CAS 42013-65-0C₁₄H₁₆N₂O₄

Barbituric acid, 5-ethyl-3-(methoxymethyl)-1-methyl-5-phenyl- chemical structure, C15H18N2O4, CAS 42061-68-7

Barbituric acid, 5-ethyl-3-(methoxymethyl)-1-methyl-5-phenyl-

CAS 42061-68-7C₁₅H₁₈N₂O₄

Barbituric acid, 1-(butoxymethyl)-5-ethyl-5-phenyl- chemical structure, C17H22N2O4, CAS 50884-84-9

Barbituric acid, 1-(butoxymethyl)-5-ethyl-5-phenyl-

CAS 50884-84-9C₁₇H₂₂N₂O₄

Barbituric acid, 5-isobutyl-5-phenyl- chemical structure, C14H16N2O3, CAS 56383-73-4

Barbituric acid, 5-isobutyl-5-phenyl-

CAS 56383-73-4C₁₄H₁₆N₂O₃

Barbituric acid, 5-phenyl-5-propyl- chemical structure, C13H14N2O3, CAS 56410-95-8

Barbituric acid, 5-phenyl-5-propyl-

CAS 56410-95-8C₁₃H₁₄N₂O₃

1-Ethoxy-3-(5-ethyl-4-hydroxy-2,6-dioxo-5-phenyl-5,6-dihydropyrimidin-1(2H)-yl)propan-2-yl hydrogen carbonimidate chemical structure, C18H23N3O6, CAS 64038-08-0

1-Ethoxy-3-(5-ethyl-4-hydroxy-2,6-dioxo-5-phenyl-5,6-dihydropyrimidin-1(2H)-yl)propan-2-yl hydrogen carbonimidate

CAS 64038-08-0C₁₈H₂₃N₃O₆

5-(p-Aminophenyl)-5-ethyl-1-methylbarbituric acid chemical structure, C13H15N3O3, CAS 64038-09-1

5-(p-Aminophenyl)-5-ethyl-1-methylbarbituric acid

CAS 64038-09-1C₁₃H₁₅N₃O₃

1-(5-Ethyl-4-hydroxy-2,6-dioxo-5-phenyl-5,6-dihydropyrimidin-1(2H)-yl)-3-(2-methylpropoxy)propan-2-yl hydrogen carbonimidate chemical structure, C20H27N3O6, CAS 64038-11-5

1-(5-Ethyl-4-hydroxy-2,6-dioxo-5-phenyl-5,6-dihydropyrimidin-1(2H)-yl)-3-(2-methylpropoxy)propan-2-yl hydrogen carbonimidate

CAS 64038-11-5C₂₀H₂₇N₃O₆