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Murcko scaffold

2-(Azetidin-1-yl)pyrimidine scaffold

240 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
240
With full pages
3
Scaffold SMILES

c1cnc(N2CCC2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Azetidin-1-yl)pyrimidine page
Murcko scaffold c1cnc(N2CCC2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 240 chemicals

5-Bromo-2-[3-(2-methoxyethoxy)azetidin-1-yl]pyrimidine chemical structure, C10H14BrN3O2, CAS 1400755-53-4
5-Bromo-2-[3-(2-methoxyethoxy)azetidin-1-yl]pyrimidine
CAS 1400755-53-4C10H14BrN3O2
1-(5-Aminopyrimidin-2-yl)azetidin-3-ol chemical structure, C7H10N4O, CAS 1445153-73-0
1-(5-Aminopyrimidin-2-yl)azetidin-3-ol
CAS 1445153-73-0C7H10N4O
1-(5-Bromo-4-methyl-2-pyrimidinyl)-3-azetidinemethanol chemical structure, C9H12BrN3O, CAS 1578253-43-6
1-(5-Bromo-4-methyl-2-pyrimidinyl)-3-azetidinemethanol
CAS 1578253-43-6C9H12BrN3O
1-(5-Bromo-4-methyl-2-pyrimidinyl)-3-azetidinecarboxamide chemical structure, C9H11BrN4O, CAS 1578253-59-4
1-(5-Bromo-4-methyl-2-pyrimidinyl)-3-azetidinecarboxamide
CAS 1578253-59-4C9H11BrN4O
N-Methyl-1-(pyrimidin-2-yl)azetidin-3-amine dihydrochloride chemical structure, C8H14Cl2N4, CAS 2097968-86-8
N-Methyl-1-(pyrimidin-2-yl)azetidin-3-amine dihydrochloride
CAS 2097968-86-8C8H14Cl2N4
N-Methyl-1-(pyrimidin-2-yl)azetidin-3-amine chemical structure, C8H12N4, CAS 1936231-35-4
N-Methyl-1-(pyrimidin-2-yl)azetidin-3-amine
CAS 1936231-35-4C8H12N4
1-(5-Chloropyrimidin-2-yl)-N-methylazetidin-3-amine dihydrochloride chemical structure, C8H13Cl3N4, CAS 2097968-91-5
1-(5-Chloropyrimidin-2-yl)-N-methylazetidin-3-amine dihydrochloride
CAS 2097968-91-5C8H13Cl3N4
1-(5-Bromopyrimidin-2-yl)-N-methylazetidin-3-amine dihydrochloride chemical structure, C8H13BrCl2N4, CAS 2098134-31-5
1-(5-Bromopyrimidin-2-yl)-N-methylazetidin-3-amine dihydrochloride
CAS 2098134-31-5C8H13BrCl2N4
1-(5-Bromopyrimidin-2-yl)-N-methylazetidin-3-amine chemical structure, C8H11BrN4, CAS 1934808-44-2
1-(5-Bromopyrimidin-2-yl)-N-methylazetidin-3-amine
CAS 1934808-44-2C8H11BrN4
1-(5-Fluoropyrimidin-2-yl)-N-methylazetidin-3-amine dihydrochloride chemical structure, C8H13Cl2FN4, CAS 2098096-62-7
1-(5-Fluoropyrimidin-2-yl)-N-methylazetidin-3-amine dihydrochloride
CAS 2098096-62-7C8H13Cl2FN4
1-(5-Fluoropyrimidin-2-yl)azetidin-3-amine chemical structure, C7H9FN4, CAS 1564933-21-6
1-(5-Fluoropyrimidin-2-yl)azetidin-3-amine
CAS 1564933-21-6C7H9FN4
1-(2-Pyrimidinyl)-3-azetidinecarboxaldehyde chemical structure, C8H9N3O, CAS 1554392-29-8
1-(2-Pyrimidinyl)-3-azetidinecarboxaldehyde
CAS 1554392-29-8C8H9N3O
1-(4,6-Dimethylpyrimidin-2-yl)azetidine-3-carbonitrile chemical structure, C10H12N4, CAS 2034418-47-6
1-(4,6-Dimethylpyrimidin-2-yl)azetidine-3-carbonitrile
CAS 2034418-47-6C10H12N4
5-Bromo-2-[3-(difluoromethyl)azetidin-1-yl]pyrimidine chemical structure, C8H8BrF2N3, CAS 2034420-34-1
5-Bromo-2-[3-(difluoromethyl)azetidin-1-yl]pyrimidine
CAS 2034420-34-1C8H8BrF2N3
5-Chloro-2-[3-(difluoromethyl)azetidin-1-yl]pyrimidine chemical structure, C8H8ClF2N3, CAS 2034514-54-8
5-Chloro-2-[3-(difluoromethyl)azetidin-1-yl]pyrimidine
CAS 2034514-54-8C8H8ClF2N3
1-(5-Fluoropyrimidin-2-yl)azetidine-3-carbonitrile chemical structure, C8H7FN4, CAS 1861965-10-7
1-(5-Fluoropyrimidin-2-yl)azetidine-3-carbonitrile
CAS 1861965-10-7C8H7FN4
1-(5-Chloropyrimidin-2-yl)azetidine-3-carbonitrile chemical structure, C8H7ClN4, CAS 1876666-36-2
1-(5-Chloropyrimidin-2-yl)azetidine-3-carbonitrile
CAS 1876666-36-2C8H7ClN4
2-[3-(Fluoromethyl)azetidin-1-yl]-N,N-dimethylpyrimidin-4-amine chemical structure, C10H15FN4, CAS 2034514-30-0
2-[3-(Fluoromethyl)azetidin-1-yl]-N,N-dimethylpyrimidin-4-amine
CAS 2034514-30-0C10H15FN4
2-(Azetidin-1-yl)pyrimidin-5-amine chemical structure, C7H10N4, CAS 1849329-61-8
2-(Azetidin-1-yl)pyrimidin-5-amine
CAS 1849329-61-8C7H10N4
2-(3-Methoxyazetidin-1-yl)pyrimidin-5-amine chemical structure, C8H12N4O, CAS 1865107-02-3
2-(3-Methoxyazetidin-1-yl)pyrimidin-5-amine
CAS 1865107-02-3C8H12N4O
1-(5-Bromo-4-methyl-2-pyrimidinyl)-3-methyl-3-azetidinol chemical structure, C9H12BrN3O, CAS 1899906-04-7
1-(5-Bromo-4-methyl-2-pyrimidinyl)-3-methyl-3-azetidinol
CAS 1899906-04-7C9H12BrN3O
1-[4-(Trifluoromethyl)pyrimidin-2-yl]azetidine-3-carbonitrile chemical structure, C9H7F3N4, CAS 2034513-15-8
1-[4-(Trifluoromethyl)pyrimidin-2-yl]azetidine-3-carbonitrile
CAS 2034513-15-8C9H7F3N4
1-(5-Bromopyrimidin-2-yl)azetidine-3-carbonitrile chemical structure, C8H7BrN4, CAS 1855798-39-8
1-(5-Bromopyrimidin-2-yl)azetidine-3-carbonitrile
CAS 1855798-39-8C8H7BrN4
1-[4-(Dimethylamino)pyrimidin-2-yl]azetidine-3-carbonitrile chemical structure, C10H13N5, CAS 2034513-20-5
1-[4-(Dimethylamino)pyrimidin-2-yl]azetidine-3-carbonitrile
CAS 2034513-20-5C10H13N5