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Murcko scaffold

2-(Thiophen-2-yl)imidazo[1,2-a]pyridine scaffold

80 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
80
With full pages
5
Scaffold SMILES

c1csc(-c2cn3ccccc3n2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Thiophen-2-yl)imidazo[1,2-a]pyridine page
Murcko scaffold c1csc(-c2cn3ccccc3n2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 80 chemicals

Imidazo(1,2-a)pyridine, 7-methyl-3-nitroso-2-(2-thienyl)- chemical structure, C12H9N3OS, CAS 364043-79-8
Imidazo(1,2-a)pyridine, 7-methyl-3-nitroso-2-(2-thienyl)-
CAS 364043-79-8C12H9N3OS
2-(5-Bromothiophen-2-yl)-7-methylimidazo[1,2-a]pyridine chemical structure, C12H9BrN2S, CAS 342385-20-0
2-(5-Bromothiophen-2-yl)-7-methylimidazo[1,2-a]pyridine
CAS 342385-20-0C12H9BrN2S
6-Bromo-2-(thiophen-2-yl)imidazo[1,2-a]pyridine chemical structure, C11H7BrN2S, CAS 4045-00-5
6-Bromo-2-(thiophen-2-yl)imidazo[1,2-a]pyridine
CAS 4045-00-5C11H7BrN2S
2-(5-Bromo-2-thienyl)imidazo[1,2-a]pyridine chemical structure, C11H7BrN2S, CAS 4045-02-7
2-(5-Bromo-2-thienyl)imidazo[1,2-a]pyridine
CAS 4045-02-7C11H7BrN2S
3-{[2-(Thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]carbamoyl}propanoic acid chemical structure, C15H13N3O3S, CAS 625078-78-6
3-{[2-(Thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]carbamoyl}propanoic acid
CAS 625078-78-6C15H13N3O3S
2-Methyl-N-[2-(thiophen-2-yl)imidazo[1,2-A]pyridin-3-yl]propanamide chemical structure, C15H15N3OS, CAS 429642-99-9
2-Methyl-N-[2-(thiophen-2-yl)imidazo[1,2-A]pyridin-3-yl]propanamide
CAS 429642-99-9C15H15N3OS
N-[2-(Thiophen-2-yl)imidazo[1,2-A]pyridin-3-yl]butanamide chemical structure, C15H15N3OS, CAS 429650-41-9
N-[2-(Thiophen-2-yl)imidazo[1,2-A]pyridin-3-yl]butanamide
CAS 429650-41-9C15H15N3OS
3-Methyl-N-[2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]butanamide chemical structure, C16H17N3OS, CAS 505065-87-2
3-Methyl-N-[2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]butanamide
CAS 505065-87-2C16H17N3OS
2-(Thiophen-2-yl)imidazo[1,2-a]pyridine chemical structure, C11H8N2S, CAS 4045-03-8
2-(Thiophen-2-yl)imidazo[1,2-a]pyridine
CAS 4045-03-8C11H8N2S
6-Chloro-2-(thiophen-2-yl)imidazo[1,2-a]pyridine chemical structure, C11H7ClN2S, CAS 35368-93-5
6-Chloro-2-(thiophen-2-yl)imidazo[1,2-a]pyridine
CAS 35368-93-5C11H7ClN2S
2-(5-Bromothiophen-2-yl)-6-chloroimidazo[1,2-a]pyridine chemical structure, C11H6BrClN2S, CAS 439107-51-4
2-(5-Bromothiophen-2-yl)-6-chloroimidazo[1,2-a]pyridine
CAS 439107-51-4C11H6BrClN2S
3-Bromo-2-(2-thienyl)imidazo[1,2-a]pyridine chemical structure, C11H7BrN2S, CAS 4044-96-6
3-Bromo-2-(2-thienyl)imidazo[1,2-a]pyridine
CAS 4044-96-6C11H7BrN2S
7-Methyl-2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-amine chemical structure, C12H11N3S, CAS 851721-87-4
7-Methyl-2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-amine
CAS 851721-87-4C12H11N3S
N-[2-(Thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]pentanamide chemical structure, C16H17N3OS, CAS 850930-27-7
N-[2-(Thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]pentanamide
CAS 850930-27-7C16H17N3OS
2-(2-Thienyl)imidazo[1,2-a]pyridine-7-carboxylic Acid chemical structure, C12H8N2O2S, CAS 928003-75-2
2-(2-Thienyl)imidazo[1,2-a]pyridine-7-carboxylic Acid
CAS 928003-75-2C12H8N2O2S
2-(5-Chlorothiophen-2-yl)-6-methylimidazo[1,2-a]pyridine chemical structure, C12H9ClN2S, CAS 88594-29-0
2-(5-Chlorothiophen-2-yl)-6-methylimidazo[1,2-a]pyridine
CAS 88594-29-0C12H9ClN2S
[2-(5-Chlorothiophen-2-yl)-6-methylimidazo[1,2-a]pyridin-3-yl]acetonitrile chemical structure, C14H10ClN3S, CAS 88594-28-9
[2-(5-Chlorothiophen-2-yl)-6-methylimidazo[1,2-a]pyridin-3-yl]acetonitrile
CAS 88594-28-9C14H10ClN3S
Imidazo(1,2-a)pyridine-3-acetamide, 6-methyl-2-(5-methyl-2-thienyl)- chemical structure, C15H15N3OS, CAS 88594-34-7
Imidazo(1,2-a)pyridine-3-acetamide, 6-methyl-2-(5-methyl-2-thienyl)-
CAS 88594-34-7C15H15N3OS
Imidazo(1,2-a)pyridine-3-acetamide, N,N,6-trimethyl-2-(5-methyl-2-thienyl)- chemical structure, C17H19N3OS, CAS 88570-85-8
Imidazo(1,2-a)pyridine-3-acetamide, N,N,6-trimethyl-2-(5-methyl-2-thienyl)-
CAS 88570-85-8C17H19N3OS
Imidazo(1,2-a)pyridine-3-acetamide, 2-(5-ethyl-2-thienyl)-N,N,6-trimethyl- chemical structure, C18H21N3OS, CAS 88570-86-9
Imidazo(1,2-a)pyridine-3-acetamide, 2-(5-ethyl-2-thienyl)-N,N,6-trimethyl-
CAS 88570-86-9C18H21N3OS
Imidazo(1,2-a)pyridine-3-acetamide, 6-chloro-2-(5-chloro-2-thienyl)- chemical structure, C13H9Cl2N3OS, CAS 88570-87-0
Imidazo(1,2-a)pyridine-3-acetamide, 6-chloro-2-(5-chloro-2-thienyl)-
CAS 88570-87-0C13H9Cl2N3OS
Imidazo(1,2-a)pyridine-3-acetamide, 6-chloro-2-(5-chloro-2-thienyl)-N,N-dimethyl- chemical structure, C15H13Cl2N3OS, CAS 88570-88-1
Imidazo(1,2-a)pyridine-3-acetamide, 6-chloro-2-(5-chloro-2-thienyl)-N,N-dimethyl-
CAS 88570-88-1C15H13Cl2N3OS
Imidazo(1,2-a)pyridine-3-acetamide, 6-chloro-2-(5-chloro-2-thienyl)-N,N-dipropyl- chemical structure, C19H21Cl2N3OS, CAS 88570-89-2
Imidazo(1,2-a)pyridine-3-acetamide, 6-chloro-2-(5-chloro-2-thienyl)-N,N-dipropyl-
CAS 88570-89-2C19H21Cl2N3OS
Imidazo(1,2-a)pyridine-3-acetamide, 2-(5-chloro-2-thienyl)-6-methyl- chemical structure, C14H12ClN3OS, CAS 88570-90-5
Imidazo(1,2-a)pyridine-3-acetamide, 2-(5-chloro-2-thienyl)-6-methyl-
CAS 88570-90-5C14H12ClN3OS