Murcko scaffold
1-Phenethyl-3-phenylurea scaffold
220 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 18
- Chemicals
- 220
- With full pages
- 17
Scaffold SMILES
O=C(NCCc1ccccc1)Nc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 220 chemicals
1-Phenethyl-3-phenylurea
CAS 18006-56-9C15H16N2O
Urea, 1-(alpha-(hydroxymethyl)phenethyl)-3-phenyl-
CAS 19071-54-6C16H18N2O2
![1-Ethyl-3-(4-methylphenyl)-1-[1-[3-(trifluoromethyl)phenyl]propan-2-yl]urea chemical structure, C20H23F3N2O, CAS 51169-85-8](/s/ANYHAIAYUNZQGA-UHFFFAOYSA-N.svg)
1-Ethyl-3-(4-methylphenyl)-1-[1-[3-(trifluoromethyl)phenyl]propan-2-yl]urea
CAS 51169-85-8C20H23F3N2O
![L-Phenylalanine, N-[(phenylamino)carbonyl]- chemical structure, C16H16N2O3, CAS 33558-02-0](/s/KKVMJJXFKMILSZ-AWEZNQCLSA-N.svg)
L-Phenylalanine, N-[(phenylamino)carbonyl]-
CAS 33558-02-0C16H16N2O3
![1-(4-Chlorophenyl)-3-[2-(3,4-dimethoxyphenyl)ethyl]urea chemical structure, C17H19ClN2O3, CAS 412965-35-6](/s/KHGLUQBJFCWTSP-UHFFFAOYSA-N.svg)
1-(4-Chlorophenyl)-3-[2-(3,4-dimethoxyphenyl)ethyl]urea
CAS 412965-35-6C17H19ClN2O3
![1-[2-(4-Chlorophenyl)ethyl]-3-(4-fluorophenyl)urea chemical structure, C15H14ClFN2O, CAS 701217-24-5](/s/BAFDJLMJBCZGJA-UHFFFAOYSA-N.svg)
1-[2-(4-Chlorophenyl)ethyl]-3-(4-fluorophenyl)urea
CAS 701217-24-5C15H14ClFN2O
N-(3,4-Dichlorophenyl)-N'-(2-phenylethyl)urea
CAS 67616-09-5C15H14Cl2N2O
![1-[2-(3,4-Dimethoxyphenyl)ethyl]-3-phenylurea chemical structure, C17H20N2O3, CAS 67616-08-4](/s/YBVMNZMKNSBVJN-UHFFFAOYSA-N.svg)
1-[2-(3,4-Dimethoxyphenyl)ethyl]-3-phenylurea
CAS 67616-08-4C17H20N2O3
![1-(2,4-Difluorophenyl)-3-[2-(3,4-dimethoxyphenyl)ethyl]urea chemical structure, C17H18F2N2O3, CAS 429630-64-8](/s/UNTZBRJFJKUVAM-UHFFFAOYSA-N.svg)
1-(2,4-Difluorophenyl)-3-[2-(3,4-dimethoxyphenyl)ethyl]urea
CAS 429630-64-8C17H18F2N2O3
((4-Ethylphenyl)carbamoyl)-L-phenylalanine
CAS 1173661-32-9C18H20N2O3
![1-[(2S)-1-Hydrazinyl-1-oxo-3-phenylpropan-2-yl]-3-(4-methoxyphenyl)urea chemical structure, C17H20N4O3, CAS 958940-23-3](/s/FUWFPSBMQILPQH-HNNXBMFYSA-N.svg)
1-[(2S)-1-Hydrazinyl-1-oxo-3-phenylpropan-2-yl]-3-(4-methoxyphenyl)urea
CAS 958940-23-3C17H20N4O3
![Methyl 2-({[2-(4-chlorophenyl)ethyl]carbamoyl}amino)benzoate chemical structure, C17H17ClN2O3, CAS 725692-19-3](/s/NOHDILWAAQBYQD-UHFFFAOYSA-N.svg)
Methyl 2-({[2-(4-chlorophenyl)ethyl]carbamoyl}amino)benzoate
CAS 725692-19-3C17H17ClN2O3
![N-[2-(3-Chlorophenyl)ethyl]-N'-(2,5-dimethoxyphenyl)urea chemical structure, C17H19ClN2O3, CAS 708223-06-7](/s/YJXLAWKGAYMKCK-UHFFFAOYSA-N.svg)
N-[2-(3-Chlorophenyl)ethyl]-N'-(2,5-dimethoxyphenyl)urea
CAS 708223-06-7C17H19ClN2O3
![1-(2-Chloro-4,5-difluorophenyl)-3-[2-(3,4-dimethoxyphenyl)ethyl]urea chemical structure, C17H17ClF2N2O3, CAS 423733-85-1](/s/SUVGXZLAGWPTDN-UHFFFAOYSA-N.svg)
1-(2-Chloro-4,5-difluorophenyl)-3-[2-(3,4-dimethoxyphenyl)ethyl]urea
CAS 423733-85-1C17H17ClF2N2O3
![4-(2-{[(3-Chlorophenyl)carbamoyl]amino}ethyl)benzenesulfonamide chemical structure, C15H16ClN3O3S, CAS 380332-57-0](/s/QQDYLFDDDSOYAC-UHFFFAOYSA-N.svg)
4-(2-{[(3-Chlorophenyl)carbamoyl]amino}ethyl)benzenesulfonamide
CAS 380332-57-0C15H16ClN3O3S
![1-[2-(3,4-Dimethoxyphenyl)ethyl]-3-(3-nitrophenyl)urea chemical structure, C17H19N3O5, CAS 710985-91-4](/s/HTXZWULWBPBZBP-UHFFFAOYSA-N.svg)
1-[2-(3,4-Dimethoxyphenyl)ethyl]-3-(3-nitrophenyl)urea
CAS 710985-91-4C17H19N3O5
![L-Tyrosine, N-[(phenylamino)carbonyl]- chemical structure, C16H16N2O4, CAS 827612-65-7](/s/RBZBYAASZSNZCI-AWEZNQCLSA-N.svg)
L-Tyrosine, N-[(phenylamino)carbonyl]-
CAS 827612-65-7C16H16N2O4
![D-Tyrosine, N-[(phenylamino)carbonyl]- chemical structure, C16H16N2O4, CAS 827612-66-8](/s/RBZBYAASZSNZCI-CQSZACIVSA-N.svg)
D-Tyrosine, N-[(phenylamino)carbonyl]-
CAS 827612-66-8C16H16N2O4
![Methyl 4,5-dimethoxy-2-[[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]carbamoylamino]benzoate chemical structure, C21H24N2O7, CAS 956046-02-9](/s/IFHNXCJJQQLXTE-INIZCTEOSA-N.svg)
Methyl 4,5-dimethoxy-2-[[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]carbamoylamino]benzoate
CAS 956046-02-9C21H24N2O7
![1-(2,5-Dimethoxyphenyl)-3-[(2R)-1-hydrazinyl-1-oxo-3-phenylpropan-2-yl]urea chemical structure, C18H22N4O4, CAS 958946-24-2](/s/IQQQJHYVISARER-OAHLLOKOSA-N.svg)
1-(2,5-Dimethoxyphenyl)-3-[(2R)-1-hydrazinyl-1-oxo-3-phenylpropan-2-yl]urea
CAS 958946-24-2C18H22N4O4
![1-(4-Bromo-2-chlorophenyl)-3-[2-(3,4-dimethoxyphenyl)ethyl]urea chemical structure, C17H18BrClN2O3, CAS 701279-92-7](/s/GLZYKMQRSRYTHJ-UHFFFAOYSA-N.svg)
1-(4-Bromo-2-chlorophenyl)-3-[2-(3,4-dimethoxyphenyl)ethyl]urea
CAS 701279-92-7C17H18BrClN2O3
![1-[2-(3,4-Dimethoxyphenyl)ethyl]-3-[2-(trifluoromethyl)phenyl]urea chemical structure, C18H19F3N2O3, CAS 701930-44-1](/s/BTMRNMHXHJZRPL-UHFFFAOYSA-N.svg)
1-[2-(3,4-Dimethoxyphenyl)ethyl]-3-[2-(trifluoromethyl)phenyl]urea
CAS 701930-44-1C18H19F3N2O3
![1-[2-(4-Fluorophenyl)ethyl]-3-(4-methylphenyl)urea chemical structure, C16H17FN2O, CAS 710318-92-6](/s/BIAJJIDHPRBYLD-UHFFFAOYSA-N.svg)
1-[2-(4-Fluorophenyl)ethyl]-3-(4-methylphenyl)urea
CAS 710318-92-6C16H17FN2O
![1-(4-Methylphenyl)-3-[2-(4-sulfamoylphenyl)ethyl]urea chemical structure, C16H19N3O3S, CAS 774552-36-2](/s/YUEGIDLRWKRGSD-UHFFFAOYSA-N.svg)
1-(4-Methylphenyl)-3-[2-(4-sulfamoylphenyl)ethyl]urea
CAS 774552-36-2C16H19N3O3S
- 1-(3,4-Dichlorophenyl)-3-[2-(4-sulfamoylphenyl)ethyl]urea207795-76-4C15H15Cl2N3O3S
- 1-[2-(3,4-Dimethoxyphenyl)ethyl]-3-(2-methylphenyl)urea301689-75-8C18H22N2O3
- 1-(4-Chlorophenyl)-3-[2-(4-chlorophenyl)ethyl]urea666701-95-7C15H14Cl2N2O
- 1-[2-(4-Methoxyphenyl)ethyl]-3-(3-nitrophenyl)urea881989-06-6C16H17N3O4
- Urea, N-(2-phenylethyl)-N'-(3,4,5-trimethoxyphenyl)-68061-10-9C18H22N2O4
- Urea, N-(2-(4-chlorophenyl)ethyl)-N-(3,4,5-trimethoxyphenyl)-68061-11-0C18H21ClN2O4
- Urea, N-(4-bromophenyl)-N'-(2-phenylethyl)-64202-91-1C15H15BrN2O
- N-(1-Benzyl-2-hydroxyethyl)-N'-(3-fluorophenyl)urea478040-63-0C16H17FN2O2
- 1-Phenyl-3-(2-(4-sulfamoylphenyl)ethyl)urea10080-04-3C15H17N3O3S
- 1-(4-tert-Butylphenyl)-3-(1-phenylpropan-2-yl)urea696619-94-0C20H26N2O
- 3-(3-Bromophenyl)-1-methyl-1-phenethylurea1024470-96-9C16H17BrN2O
- Rticbm-189551909-15-0C15H14Cl2N2O
- N-(1-Benzyl-2-hydroxyethyl)-N'-(4-chlorophenyl)urea338962-96-2C16H17ClN2O2
- N-[(2-Chlorophenyl)carbamoyl]phenylalanine88857-87-8C16H15ClN2O3
- 1-(3-Fluorophenyl)-3-[2-(4-fluorophenyl)ethyl]urea899019-15-9C15H14F2N2O
- 1-(2,5-Dimethylphenyl)-3-(2-phenylethyl)urea894150-04-0C17H20N2O
- 1-[2-(3-Chlorophenyl)ethyl]-3-(4-fluorophenyl)urea890297-04-8C15H14ClFN2O
- 1-(4-Ethoxyphenyl)-3-(2-phenylethyl)urea891430-69-6C17H20N2O2
- 1-(2,5-Dimethoxyphenyl)-3-[2-(4-fluorophenyl)ethyl]urea893024-69-6C17H19FN2O3
- 1-[2-(4-Fluorophenyl)ethyl]-3-(2-methylphenyl)urea888284-84-2C16H17FN2O
- 1-[2-(3-Chlorophenyl)ethyl]-3-(2-fluorophenyl)urea890297-12-8C15H14ClFN2O
- 1-(4-Fluorophenyl)-3-[2-(2-methoxyphenyl)ethyl]urea894261-48-4C16H17FN2O2
- 1-[2-(4-Fluorophenyl)ethyl]-3-(2-methoxyphenyl)urea894261-76-8C16H17FN2O2
- 1-[2-(4-Chlorophenyl)ethyl]-3-(2-methylphenyl)urea894251-38-8C16H17ClN2O
Related scaffolds
Same ring framework with different atoms or bond orders
S=C(NN=Cc1ccccc1)Nc1ccccc1105 chemicals
S=C(NCCc1ccccc1)Nc1ccccc160 chemicals
c1ccc(CCNCCc2ccccc2)cc158 chemicals
O=C(COc1ccccc1)NCc1ccccc146 chemicals
O=C(NCCOc1ccccc1)c1ccccc146 chemicals
O=C(C=Cc1ccccc1)NCc1ccccc143 chemicals
c1ccc(OCCCOc2ccccc2)cc141 chemicals
O=C(CC(=O)Nc1ccccc1)Nc1ccccc137 chemicals
O=C(CNS(=O)(=O)c1ccccc1)Nc1ccccc136 chemicals
O=C(CSCc1ccccc1)Nc1ccccc133 chemicals
O=C(Cc1ccccc1)NCCc1ccccc132 chemicals
O=C(CNCc1ccccc1)Nc1ccccc131 chemicals