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Murcko scaffold

1-(2-Morpholin-4-yl-2-oxoethyl)-1H-indole scaffold

56 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
56
With full pages
4
Scaffold SMILES

O=C(Cn1ccc2ccccc21)N1CCOCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(2-Morpholin-4-yl-2-oxoethyl)-1H-indole page
Murcko scaffold O=C(Cn1ccc2ccccc21)N1CCOCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 56 chemicals

2-Methyl-1-(2-morpholin-4-yl-2-oxo-ethyl)-1H-indole-3-carbaldehyde chemical structure, C16H18N2O3, CAS 433707-36-9
2-Methyl-1-(2-morpholin-4-yl-2-oxo-ethyl)-1H-indole-3-carbaldehyde
CAS 433707-36-9C16H18N2O3
1-(2-Morpholin-4-yl-2-oxo-ethyl)-1H-indole-3-carbaldehyde chemical structure, C15H16N2O3, CAS 335207-46-0
1-(2-Morpholin-4-yl-2-oxo-ethyl)-1H-indole-3-carbaldehyde
CAS 335207-46-0C15H16N2O3
7-Ethyl-1-(2-morpholin-4-yl-2-oxoethyl)indole-3-carbaldehyde chemical structure, C17H20N2O3, CAS 593237-23-1
7-Ethyl-1-(2-morpholin-4-yl-2-oxoethyl)indole-3-carbaldehyde
CAS 593237-23-1C17H20N2O3
1-Morpholin-4-yl-2-[3-[(E)-2-nitroethenyl]indol-1-yl]ethanone chemical structure, C16H17N3O4, CAS 625411-47-4
1-Morpholin-4-yl-2-[3-[(E)-2-nitroethenyl]indol-1-yl]ethanone
CAS 625411-47-4C16H17N3O4
2-(3-Acetyl-1H-indol-1-yl)-1-(morpholin-4-yl)ethanone chemical structure, C16H18N2O3, CAS 842971-67-9
2-(3-Acetyl-1H-indol-1-yl)-1-(morpholin-4-yl)ethanone
CAS 842971-67-9C16H18N2O3
2,2,2-Trifluoro-1-[1-(2-morpholin-4-yl-2-oxoethyl)indol-3-yl]ethanone chemical structure, C16H15F3N2O3, CAS 510722-10-8
2,2,2-Trifluoro-1-[1-(2-morpholin-4-yl-2-oxoethyl)indol-3-yl]ethanone
CAS 510722-10-8C16H15F3N2O3
Morpholine, 4-((2-methyl-1H-indol-1-yl)acetyl)- chemical structure, C15H18N2O2, CAS 163629-12-7
Morpholine, 4-((2-methyl-1H-indol-1-yl)acetyl)-
CAS 163629-12-7C15H18N2O2
1-(2-Morpholin-4-yl-2-oxoethyl)-1H-indole chemical structure, C14H16N2O2, CAS 677733-57-2
1-(2-Morpholin-4-yl-2-oxoethyl)-1H-indole
CAS 677733-57-2C14H16N2O2
5-Bromo-1-[2-(4-morpholinyl)-2-oxoethyl]-1H-indole chemical structure, C14H15BrN2O2, CAS 676641-48-8
5-Bromo-1-[2-(4-morpholinyl)-2-oxoethyl]-1H-indole
CAS 676641-48-8C14H15BrN2O2
N,N-Dimethyl-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide chemical structure, C18H21N3O4, CAS 872855-01-1
N,N-Dimethyl-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide
CAS 872855-01-1C18H21N3O4
N,N-Diethyl-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide chemical structure, C20H25N3O4, CAS 865418-01-5
N,N-Diethyl-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide
CAS 865418-01-5C20H25N3O4
N,N-Diisopropyl-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide chemical structure, C22H29N3O4, CAS 872855-02-2
N,N-Diisopropyl-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide
CAS 872855-02-2C22H29N3O4
N-Methyl-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide chemical structure, C17H19N3O4, CAS 872855-38-4
N-Methyl-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide
CAS 872855-38-4C17H19N3O4
N-Ethyl-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide chemical structure, C18H21N3O4, CAS 872855-39-5
N-Ethyl-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide
CAS 872855-39-5C18H21N3O4
2-(1-(2-Morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxo-N-propylacetamide chemical structure, C19H23N3O4, CAS 872855-40-8
2-(1-(2-Morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxo-N-propylacetamide
CAS 872855-40-8C19H23N3O4
N-Butyl-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide chemical structure, C20H25N3O4, CAS 872855-41-9
N-Butyl-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide
CAS 872855-41-9C20H25N3O4
N-Isopropyl-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide chemical structure, C19H23N3O4, CAS 872855-42-0
N-Isopropyl-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide
CAS 872855-42-0C19H23N3O4
N-Isobutyl-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide chemical structure, C20H25N3O4, CAS 872855-43-1
N-Isobutyl-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide
CAS 872855-43-1C20H25N3O4
N-(sec-Butyl)-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide chemical structure, C20H25N3O4, CAS 872855-44-2
N-(sec-Butyl)-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide
CAS 872855-44-2C20H25N3O4
N-tert-Butyl-2-[1-(2-morpholin-4-yl-2-oxoethyl)indol-3-yl]-2-oxoacetamide chemical structure, C20H25N3O4, CAS 872855-45-3
N-tert-Butyl-2-[1-(2-morpholin-4-yl-2-oxoethyl)indol-3-yl]-2-oxoacetamide
CAS 872855-45-3C20H25N3O4
N-Allyl-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide chemical structure, C19H21N3O4, CAS 872855-46-4
N-Allyl-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide
CAS 872855-46-4C19H21N3O4
N-Isopentyl-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide chemical structure, C21H27N3O4, CAS 872855-47-5
N-Isopentyl-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide
CAS 872855-47-5C21H27N3O4
N-(2-Methoxyethyl)-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide chemical structure, C19H23N3O5, CAS 872855-48-6
N-(2-Methoxyethyl)-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide
CAS 872855-48-6C19H23N3O5
N-(3-Methoxypropyl)-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide chemical structure, C20H25N3O5, CAS 872855-49-7
N-(3-Methoxypropyl)-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide
CAS 872855-49-7C20H25N3O5