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Murcko scaffold

Ring system with 3 rings and 19 atoms

21 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
21
With full pages
5
Scaffold SMILES

O=C1OC(C=CNc2ccccc2)c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1OC(C=CNc2ccccc2)c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

3-[2-(4-Methoxyanilino)-1-nitroethenyl]-3H-2-benzofuran-1-one chemical structure, C17H14N2O5
3-[2-(4-Methoxyanilino)-1-nitroethenyl]-3H-2-benzofuran-1-one
C17H14N2O5
3-[2-(4-Chloroanilino)-1-nitrovinyl]-2-benzofuran-1(3H)-one chemical structure, C16H11ClN2O4
3-[2-(4-Chloroanilino)-1-nitrovinyl]-2-benzofuran-1(3H)-one
C16H11ClN2O4
3-{1-Nitro-2-[4-(trifluoromethoxy)anilino]vinyl}-2-benzofuran-1(3H)-one chemical structure, C17H11F3N2O5
3-{1-Nitro-2-[4-(trifluoromethoxy)anilino]vinyl}-2-benzofuran-1(3H)-one
C17H11F3N2O5
3-{2-[4-(tert-Butyl)anilino]-1-nitrovinyl}-2-benzofuran-1(3H)-one chemical structure, C20H20N2O4, CAS 339023-62-0
3-{2-[4-(tert-Butyl)anilino]-1-nitrovinyl}-2-benzofuran-1(3H)-one
CAS 339023-62-0C20H20N2O4
3-[2-(4-Methoxyanilino)-1-nitrovinyl]-2-benzofuran-1(3H)-one chemical structure, C17H14N2O5, CAS 339023-58-4
3-[2-(4-Methoxyanilino)-1-nitrovinyl]-2-benzofuran-1(3H)-one
CAS 339023-58-4C17H14N2O5
3-[2-(2,4-Dimethylanilino)-1-nitrovinyl]-2-benzofuran-1(3H)-one chemical structure, C18H16N2O4, CAS 320420-47-1
3-[2-(2,4-Dimethylanilino)-1-nitrovinyl]-2-benzofuran-1(3H)-one
CAS 320420-47-1C18H16N2O4
3-[(Z)-2-(4-Chloroanilino)-1-nitroethenyl]-3H-2-benzofuran-1-one chemical structure, C16H11ClN2O4
3-[(Z)-2-(4-Chloroanilino)-1-nitroethenyl]-3H-2-benzofuran-1-one
C16H11ClN2O4
3-[(Z)-1-Nitro-2-[4-(trifluoromethoxy)anilino]ethenyl]-3H-2-benzofuran-1-one chemical structure, C17H11F3N2O5
3-[(Z)-1-Nitro-2-[4-(trifluoromethoxy)anilino]ethenyl]-3H-2-benzofuran-1-one
C17H11F3N2O5
3-(2-Anilino-1-nitrovinyl)-2-benzofuran-1(3H)-one chemical structure, C16H12N2O4, CAS 338753-92-7
3-(2-Anilino-1-nitrovinyl)-2-benzofuran-1(3H)-one
CAS 338753-92-7C16H12N2O4
3-[2-(2,4-Difluoroanilino)-1-nitrovinyl]-2-benzofuran-1(3H)-one chemical structure, C16H10F2N2O4, CAS 320420-45-9
3-[2-(2,4-Difluoroanilino)-1-nitrovinyl]-2-benzofuran-1(3H)-one
CAS 320420-45-9C16H10F2N2O4
3-[2-(5-Chloro-2-hydroxyanilino)-1-nitrovinyl]-2-benzofuran-1(3H)-one chemical structure, C16H11ClN2O5, CAS 320420-38-0
3-[2-(5-Chloro-2-hydroxyanilino)-1-nitrovinyl]-2-benzofuran-1(3H)-one
CAS 320420-38-0C16H11ClN2O5
3-[(E)-2-[(3,5-Dichlorophenyl)amino]-1-nitroethenyl]-1,3-dihydro-2-benzofuran-1-one chemical structure, C16H10Cl2N2O4, CAS 320420-36-8
3-[(E)-2-[(3,5-Dichlorophenyl)amino]-1-nitroethenyl]-1,3-dihydro-2-benzofuran-1-one
CAS 320420-36-8C16H10Cl2N2O4
3-[2-(3-Chloroanilino)-1-nitrovinyl]-2-benzofuran-1(3H)-one chemical structure, C16H11ClN2O4, CAS 320420-37-9
3-[2-(3-Chloroanilino)-1-nitrovinyl]-2-benzofuran-1(3H)-one
CAS 320420-37-9C16H11ClN2O4
3-{1-Nitro-2-[3-(trifluoromethyl)anilino]vinyl}-2-benzofuran-1(3H)-one chemical structure, C17H11F3N2O4, CAS 320420-39-1
3-{1-Nitro-2-[3-(trifluoromethyl)anilino]vinyl}-2-benzofuran-1(3H)-one
CAS 320420-39-1C17H11F3N2O4
3-[(E)-1-Nitro-2-{[4-(trifluoromethoxy)phenyl]amino}ethenyl]-1,3-dihydro-2-benzofuran-1-one chemical structure, C17H11F3N2O5, CAS 320420-40-4
3-[(E)-1-Nitro-2-{[4-(trifluoromethoxy)phenyl]amino}ethenyl]-1,3-dihydro-2-benzofuran-1-one
CAS 320420-40-4C17H11F3N2O5
4-{[2-Nitro-2-(3-oxo-1,3-dihydro-2-benzofuran-1-yl)vinyl]amino}benzenecarboxylic acid chemical structure, C17H12N2O6, CAS 320420-41-5
4-{[2-Nitro-2-(3-oxo-1,3-dihydro-2-benzofuran-1-yl)vinyl]amino}benzenecarboxylic acid
CAS 320420-41-5C17H12N2O6
3-[(E)-2-[(4-Chlorophenyl)amino]-1-nitroethenyl]-1,3-dihydro-2-benzofuran-1-one chemical structure, C16H11ClN2O4, CAS 338753-94-9
3-[(E)-2-[(4-Chlorophenyl)amino]-1-nitroethenyl]-1,3-dihydro-2-benzofuran-1-one
CAS 338753-94-9C16H11ClN2O4
3-[2-(4-Fluoroanilino)-1-nitrovinyl]-2-benzofuran-1(3H)-one chemical structure, C16H11FN2O4, CAS 339023-52-8
3-[2-(4-Fluoroanilino)-1-nitrovinyl]-2-benzofuran-1(3H)-one
CAS 339023-52-8C16H11FN2O4
3-[2-(2,4-Dichloroanilino)-1-nitrovinyl]-2-benzofuran-1(3H)-one chemical structure, C16H10Cl2N2O4, CAS 339023-54-0
3-[2-(2,4-Dichloroanilino)-1-nitrovinyl]-2-benzofuran-1(3H)-one
CAS 339023-54-0C16H10Cl2N2O4
3-[1-Nitro-2-(4-nitroanilino)vinyl]-2-benzofuran-1(3H)-one chemical structure, C16H11N3O6, CAS 339023-56-2
3-[1-Nitro-2-(4-nitroanilino)vinyl]-2-benzofuran-1(3H)-one
CAS 339023-56-2C16H11N3O6
3-[(Z)-2-(4-Methoxyanilino)-1-nitroethenyl]-3H-2-benzofuran-1-one chemical structure, C17H14N2O5
3-[(Z)-2-(4-Methoxyanilino)-1-nitroethenyl]-3H-2-benzofuran-1-one
C17H14N2O5