CompoundList
Sign in
Murcko scaffold

2-(Pyridin-4-yl)-N-(thiazol-2-yl)quinoline-4-carboxamide scaffold

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
8
With full pages
3
Scaffold SMILES

O=C(Nc1nccs1)c1cc(-c2ccncc2)nc2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Pyridin-4-yl)-N-(thiazol-2-yl)quinoline-4-carboxamide page
Murcko scaffold O=C(Nc1nccs1)c1cc(-c2ccncc2)nc2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

Methyl 2-({[6,8-dimethyl-2-(pyridin-4-yl)quinolin-4-yl]carbonyl}amino)-4-methyl-1,3-thiazole-5-carboxylate chemical structure, C23H20N4O3S, CAS 713118-38-8
Methyl 2-({[6,8-dimethyl-2-(pyridin-4-yl)quinolin-4-yl]carbonyl}amino)-4-methyl-1,3-thiazole-5-carboxylate
CAS 713118-38-8C23H20N4O3S
6,8-Dimethyl-2-pyridin-4-yl-N-(1,3-thiazol-2-yl)quinoline-4-carboxamide chemical structure, C20H16N4OS, CAS 713489-96-4
6,8-Dimethyl-2-pyridin-4-yl-N-(1,3-thiazol-2-yl)quinoline-4-carboxamide
CAS 713489-96-4C20H16N4OS
2-[(6,8-Dimethyl-2-pyridin-4-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide chemical structure, C24H23N5O2S, CAS 713117-89-6
2-[(6,8-Dimethyl-2-pyridin-4-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide
CAS 713117-89-6C24H23N5O2S
2-(Pyridin-4-yl)-N-(thiazol-2-yl)quinoline-4-carboxamide chemical structure, C18H12N4OS, CAS 716363-23-4
2-(Pyridin-4-yl)-N-(thiazol-2-yl)quinoline-4-carboxamide
CAS 716363-23-4C18H12N4OS
Ethyl [2-({[2-(pyridin-4-yl)quinolin-4-yl]carbonyl}amino)-1,3-thiazol-4-yl]acetate chemical structure, C22H18N4O3S, CAS 377756-34-8
Ethyl [2-({[2-(pyridin-4-yl)quinolin-4-yl]carbonyl}amino)-1,3-thiazol-4-yl]acetate
CAS 377756-34-8C22H18N4O3S
N-(4-Methyl-1,3-thiazol-2-yl)-2-(pyridin-4-yl)quinoline-4-carboxamide chemical structure, C19H14N4OS, CAS 522640-02-4
N-(4-Methyl-1,3-thiazol-2-yl)-2-(pyridin-4-yl)quinoline-4-carboxamide
CAS 522640-02-4C19H14N4OS
Ethyl 2-({[2-(pyridin-4-yl)quinolin-4-yl]carbonyl}amino)-1,3-thiazole-4-carboxylate chemical structure, C21H16N4O3S, CAS 1282143-62-7
Ethyl 2-({[2-(pyridin-4-yl)quinolin-4-yl]carbonyl}amino)-1,3-thiazole-4-carboxylate
CAS 1282143-62-7C21H16N4O3S
Methyl 4-methyl-2-({[2-(pyridin-4-yl)quinolin-4-yl]carbonyl}amino)-1,3-thiazole-5-carboxylate chemical structure, C21H16N4O3S, CAS 1401556-42-0
Methyl 4-methyl-2-({[2-(pyridin-4-yl)quinolin-4-yl]carbonyl}amino)-1,3-thiazole-5-carboxylate
CAS 1401556-42-0C21H16N4O3S