Murcko scaffold
N-Phenyl-4-(phenylsulfonamido)benzamide scaffold
74 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 25
- Chemicals
- 74
- With full pages
- 4
Scaffold SMILES
O=C(Nc1ccccc1)c1ccc(NS(=O)(=O)c2ccccc2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 74 chemicals
![4-[(2,5-Dimethylphenyl)sulfonylamino]-N-(2-fluorophenyl)benzamide chemical structure, C21H19FN2O3S, CAS 690245-01-3](/s/KRHSIUIFKZWTGT-UHFFFAOYSA-N.svg)
4-[(2,5-Dimethylphenyl)sulfonylamino]-N-(2-fluorophenyl)benzamide
CAS 690245-01-3C21H19FN2O3S
![N-(4-Bromo-2-fluorophenyl)-4-[(3-methoxyphenyl)sulfonylamino]benzamide chemical structure, C20H16BrFN2O4S, CAS 690962-43-7](/s/XNDYHXIAIIESRR-UHFFFAOYSA-N.svg)
N-(4-Bromo-2-fluorophenyl)-4-[(3-methoxyphenyl)sulfonylamino]benzamide
CAS 690962-43-7C20H16BrFN2O4S
![N-(4-Ethoxyphenyl)-4-[(3-fluorophenyl)sulfonylamino]benzamide chemical structure, C21H19FN2O4S, CAS 690643-42-6](/s/FPMCASNWYBYEBI-UHFFFAOYSA-N.svg)
N-(4-Ethoxyphenyl)-4-[(3-fluorophenyl)sulfonylamino]benzamide
CAS 690643-42-6C21H19FN2O4S
![N-(4-Bromo-2-fluorophenyl)-4-[(3-chlorophenyl)sulfonylamino]benzamide chemical structure, C19H13BrClFN2O3S, CAS 690962-32-4](/s/KAWDMSKUATWCHQ-UHFFFAOYSA-N.svg)
N-(4-Bromo-2-fluorophenyl)-4-[(3-chlorophenyl)sulfonylamino]benzamide
CAS 690962-32-4C19H13BrClFN2O3S
![N-(4-Ethoxyphenyl)-4-[[3-(trifluoromethyl)phenyl]sulfonylamino]benzamide chemical structure, C22H19F3N2O4S, CAS 690962-26-6](/s/PLVNQIZXODJGMM-UHFFFAOYSA-N.svg)
N-(4-Ethoxyphenyl)-4-[[3-(trifluoromethyl)phenyl]sulfonylamino]benzamide
CAS 690962-26-6C22H19F3N2O4S
![N-(2-Methoxyphenyl)-4-[[3-(trifluoromethyl)phenyl]sulfonylamino]benzamide chemical structure, C21H17F3N2O4S, CAS 690962-27-7](/s/HIIWVCKJLMIWQT-UHFFFAOYSA-N.svg)
N-(2-Methoxyphenyl)-4-[[3-(trifluoromethyl)phenyl]sulfonylamino]benzamide
CAS 690962-27-7C21H17F3N2O4S
![N-(2-Fluorophenyl)-4-{methyl[(4-methylphenyl)sulfonyl]amino}benzamide chemical structure, C21H19FN2O3S, CAS 642999-53-9](/s/UROFEPSHCOVOOE-UHFFFAOYSA-N.svg)
N-(2-Fluorophenyl)-4-{methyl[(4-methylphenyl)sulfonyl]amino}benzamide
CAS 642999-53-9C21H19FN2O3S
![N-(3-Acetylphenyl)-4-{methyl[(4-methylphenyl)sulfonyl]amino}benzamide chemical structure, C23H22N2O4S, CAS 641994-73-2](/s/JSAVZFADJBFKRD-UHFFFAOYSA-N.svg)
N-(3-Acetylphenyl)-4-{methyl[(4-methylphenyl)sulfonyl]amino}benzamide
CAS 641994-73-2C23H22N2O4S
![Ethyl 4-[[4-[(3,4-dimethoxyphenyl)sulfonyl-methylamino]benzoyl]amino]benzoate chemical structure, C25H26N2O7S, CAS 718600-47-6](/s/BNJIZOOJJYPUDS-UHFFFAOYSA-N.svg)
Ethyl 4-[[4-[(3,4-dimethoxyphenyl)sulfonyl-methylamino]benzoyl]amino]benzoate
CAS 718600-47-6C25H26N2O7S
![4-[(3,4-Dimethoxyphenyl)sulfonyl-methylamino]-N-(2-ethylphenyl)benzamide chemical structure, C24H26N2O5S, CAS 791804-84-7](/s/CXQTVBPGXCPCBQ-UHFFFAOYSA-N.svg)
4-[(3,4-Dimethoxyphenyl)sulfonyl-methylamino]-N-(2-ethylphenyl)benzamide
CAS 791804-84-7C24H26N2O5S
![N-(2-Bromophenyl)-4-[methyl(phenylsulfonyl)amino]benzamide chemical structure, C20H17BrN2O3S, CAS 333320-68-6](/s/SSBSLAQCLCECDY-UHFFFAOYSA-N.svg)
N-(2-Bromophenyl)-4-[methyl(phenylsulfonyl)amino]benzamide
CAS 333320-68-6C20H17BrN2O3S
![4-[Benzenesulfonyl(methyl)amino]-N-(4-bromophenyl)benzamide chemical structure, C20H17BrN2O3S, CAS 333357-92-9](/s/YQFLPIQZABQAJO-UHFFFAOYSA-N.svg)
4-[Benzenesulfonyl(methyl)amino]-N-(4-bromophenyl)benzamide
CAS 333357-92-9C20H17BrN2O3S
![4-[Benzenesulfonyl(methyl)amino]-N-(4-methoxyphenyl)benzamide chemical structure, C21H20N2O4S, CAS 357310-29-3](/s/CIWWKIHDXYMNJR-UHFFFAOYSA-N.svg)
4-[Benzenesulfonyl(methyl)amino]-N-(4-methoxyphenyl)benzamide
CAS 357310-29-3C21H20N2O4S
![4-[Benzenesulfonyl(methyl)amino]-N-(5-chloro-2-methylphenyl)benzamide chemical structure, C21H19ClN2O3S, CAS 332035-79-7](/s/TVJGKJMJSGZTOP-UHFFFAOYSA-N.svg)
4-[Benzenesulfonyl(methyl)amino]-N-(5-chloro-2-methylphenyl)benzamide
CAS 332035-79-7C21H19ClN2O3S
![4-[Benzenesulfonyl(methyl)amino]-N-(3-chloro-4-fluorophenyl)benzamide chemical structure, C20H16ClFN2O3S, CAS 332035-81-1](/s/ATHFJBVJRDHAQR-UHFFFAOYSA-N.svg)
4-[Benzenesulfonyl(methyl)amino]-N-(3-chloro-4-fluorophenyl)benzamide
CAS 332035-81-1C20H16ClFN2O3S
![4-[(3-Bromo-4-methoxyphenyl)sulfonylamino]-N-phenylbenzamide chemical structure, C20H17BrN2O4S, CAS 6158-95-8](/s/DWNCFWUSCHCUHF-UHFFFAOYSA-N.svg)
4-[(3-Bromo-4-methoxyphenyl)sulfonylamino]-N-phenylbenzamide
CAS 6158-95-8C20H17BrN2O4S
![N-(2,5-Dichlorophenyl)-4-[methyl(phenylsulfonyl)amino]benzamide chemical structure, C20H16Cl2N2O3S, CAS 357329-68-1](/s/NPRHSIFKIIGQSR-UHFFFAOYSA-N.svg)
N-(2,5-Dichlorophenyl)-4-[methyl(phenylsulfonyl)amino]benzamide
CAS 357329-68-1C20H16Cl2N2O3S
![N-(4-Ethylphenyl)-4-[methyl-(4-methylphenyl)sulfonylamino]benzamide chemical structure, C23H24N2O3S, CAS 664313-99-9](/s/LGRAYUCASCGHEQ-UHFFFAOYSA-N.svg)
N-(4-Ethylphenyl)-4-[methyl-(4-methylphenyl)sulfonylamino]benzamide
CAS 664313-99-9C23H24N2O3S
![Methyl 4-methyl-3-{[(4-{methyl[(4-methylphenyl)sulfonyl]amino}phenyl)carbonyl]amino}benzoate chemical structure, C24H24N2O5S, CAS 641608-05-1](/s/QWRXLCQXSUVAJL-UHFFFAOYSA-N.svg)
Methyl 4-methyl-3-{[(4-{methyl[(4-methylphenyl)sulfonyl]amino}phenyl)carbonyl]amino}benzoate
CAS 641608-05-1C24H24N2O5S
![N-(3-Chloro-4-methoxyphenyl)-4-[methyl(phenylsulfonyl)amino]benzamide chemical structure, C21H19ClN2O4S, CAS 700851-68-9](/s/ULVXWUQZLNUUEA-UHFFFAOYSA-N.svg)
N-(3-Chloro-4-methoxyphenyl)-4-[methyl(phenylsulfonyl)amino]benzamide
CAS 700851-68-9C21H19ClN2O4S
![N-(4-Bromo-3-methylphenyl)-4-[methyl(phenylsulfonyl)amino]benzamide chemical structure, C21H19BrN2O3S, CAS 425680-58-6](/s/RAFOWQCZXRWRGU-UHFFFAOYSA-N.svg)
N-(4-Bromo-3-methylphenyl)-4-[methyl(phenylsulfonyl)amino]benzamide
CAS 425680-58-6C21H19BrN2O3S
![N-(2-Ethoxyphenyl)-4-[(4-methylphenyl)sulfonylamino]benzamide chemical structure, C22H22N2O4S, CAS 717895-97-1](/s/LOGTWSQUJAHIMR-UHFFFAOYSA-N.svg)
N-(2-Ethoxyphenyl)-4-[(4-methylphenyl)sulfonylamino]benzamide
CAS 717895-97-1C22H22N2O4S
![N-(2-Methyl-3-nitrophenyl)-4-[(4-methylphenyl)sulfonylamino]benzamide chemical structure, C21H19N3O5S, CAS 825657-60-1](/s/WRZMYMRMKUBLBS-UHFFFAOYSA-N.svg)
N-(2-Methyl-3-nitrophenyl)-4-[(4-methylphenyl)sulfonylamino]benzamide
CAS 825657-60-1C21H19N3O5S
![N-(4-Acetamidophenyl)-4-[(4-methoxyphenyl)sulfonyl-methylamino]benzamide chemical structure, C23H23N3O5S, CAS 825658-30-8](/s/WBUIYZQZRYBHAZ-UHFFFAOYSA-N.svg)
N-(4-Acetamidophenyl)-4-[(4-methoxyphenyl)sulfonyl-methylamino]benzamide
CAS 825658-30-8C23H23N3O5S
- 4-(Benzenesulfonamido)-N-(3-chloro-4-fluorophenyl)benzamide831187-18-9C19H14ClFN2O3S
- Methyl 4-chloro-3-[({4-[(phenylsulfonyl)amino]phenyl}carbonyl)amino]benzoate831205-39-1C21H17ClN2O5S
- 4-(Benzenesulfonamido)-N-(2-ethyl-6-methylphenyl)benzamide831229-75-5C22H22N2O3S
- Methyl 3-{[(4-{[(4-methoxyphenyl)sulfonyl](methyl)amino}phenyl)carbonyl]amino}-4-methylbenzoate831250-02-3C24H24N2O6S
- N-(2,6-Dimethylphenyl)-4-[(4-methoxyphenyl)sulfonyl-methylamino]benzamide713083-62-6C23H24N2O4S
- 4-(Benzenesulfonamido)-N-(2-ethylphenyl)benzamide714259-05-9C21H20N2O3S
- Methyl 4-[({4-[(phenylsulfonyl)amino]phenyl}carbonyl)amino]benzoate713502-98-8C21H18N2O5S
- Methyl 4-{[(4-{[(4-methylphenyl)sulfonyl]amino}phenyl)carbonyl]amino}benzoate382176-37-6C22H20N2O5S
- N-(4-Fluorophenyl)-4-(3-methoxybenzenesulfonamido)benzamide690962-40-4C20H17FN2O4S
- N-(2-Ethylphenyl)-4-[(4-methylphenyl)sulfonylamino]benzamide824975-17-9C22H22N2O3S
- N-(3,4-Difluorophenyl)-4-[methyl-(4-methylphenyl)sulfonylamino]benzamide701275-29-8C21H18F2N2O3S
- N-(3,5-Dichlorophenyl)-4-[methyl-(4-methylphenyl)sulfonylamino]benzamide693270-47-2C21H18Cl2N2O3S
- N-[4-(Acetylamino)phenyl]-4-{[(5-tert-butyl-2,3-dimethylphenyl)sulfonyl]amino}benzamide670256-02-7C27H31N3O4S
- 4-[(2,5-Dimethylphenyl)sulfonylamino]-N-[3-(trifluoromethyl)phenyl]benzamide690643-69-7C22H19F3N2O3S
- N-(2,6-Diethylphenyl)-4-[methyl-(4-methylphenyl)sulfonylamino]benzamide640715-42-0C25H28N2O3S
- N-(2-Methoxy-5-nitrophenyl)-4-[methyl-(4-methylphenyl)sulfonylamino]benzamide641601-91-4C22H21N3O6S
- 4-[Methyl-(4-methylphenyl)sulfonylamino]-N-[2-(trifluoromethyl)phenyl]benzamide694502-44-8C22H19F3N2O3S
- N-(2-Methoxyphenyl)-4-[methyl-(4-methylphenyl)sulfonylamino]benzamide693269-17-9C22H22N2O4S
- Methyl 2-{[(4-{methyl[(4-methylphenyl)sulfonyl]amino}phenyl)carbonyl]amino}benzoate693811-61-9C23H22N2O5S
- 4-[Methyl-(4-methylphenyl)sulfonylamino]-N-[3-(trifluoromethyl)phenyl]benzamide693811-83-5C22H19F3N2O3S
- N-(2-Bromophenyl)-4-[methyl-(4-methylphenyl)sulfonylamino]benzamide693265-46-2C21H19BrN2O3S
- N-(4-Methoxyphenyl)-4-[methyl-(4-methylphenyl)sulfonylamino]benzamide693266-81-8C22H22N2O4S
- N-(3,5-Dimethylphenyl)-4-[methyl-(4-methylphenyl)sulfonylamino]benzamide693267-13-9C23H24N2O3S
- 4-[Methyl-(4-methylphenyl)sulfonylamino]-N-(4-propan-2-ylphenyl)benzamide693820-38-1C24H26N2O3S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1)c1ccccc137 chemicals
O=C(Nc1ccc(S(=O)(=O)Nc2ccccc2)cc1)c1ccccc119 chemicals
O=C(Nc1ccccc1)c1ccc(C(=O)Nc2ccccc2)cc119 chemicals
c1ccc(N=Nc2ccc(N=Nc3ccccc3)cc2)cc118 chemicals
O=C(Nc1ccc(NC(=O)c2ccccc2)cc1)c1ccccc116 chemicals
C(=Nc1ccc(N=Cc2ccccc2)cc1)c1ccccc116 chemicals
C(=Nc1ccccc1)c1ccc(C=Nc2ccccc2)cc116 chemicals
O=C(Oc1coc(CSc2ncccn2)cc1=O)c1ccccc113 chemicals
C(=Cc1ccc(C=Cc2ccccc2)cc1)c1ccccc112 chemicals
O=C(Oc1ccc(C(=O)Oc2ccccc2)cc1)c1ccccc112 chemicals
C(=Nc1ccccc1)c1ccc(OCc2ccccc2)cc111 chemicals
O=C(Nc1ccc(N=Nc2ccccc2)cc1)c1ccccc110 chemicals