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Murcko scaffold

1-(Pyridine-3-sulfonyl)piperazine scaffold

82 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 15
Chemicals: 82
With full pages: 5

Scaffold SMILES

O=S(=O)(c1cccnc1)N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 1-(Pyridine-3-sulfonyl)piperazine page

Murcko scaffold O=S(=O)(c1cccnc1)N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 82 chemicals

1-(6-Chloro-pyridine-3-sulfonyl)-4-methyl-piperazine chemical structure, C10H14ClN3O2S, CAS 64614-53-5

1-(6-Chloro-pyridine-3-sulfonyl)-4-methyl-piperazine

CAS 64614-53-5C₁₀H₁₄ClN₃O₂S

1-[(6-Chloro-3-pyridinyl)sulfonyl]-4-ethylpiperazine chemical structure, C11H16ClN3O2S, CAS 612487-53-3

1-[(6-Chloro-3-pyridinyl)sulfonyl]-4-ethylpiperazine

CAS 612487-53-3C₁₁H₁₆ClN₃O₂S

3-Bromo-2-chloro-5-(4-ethylpiperazin-1-ylsulfonyl)pyridine chemical structure, C11H15BrClN3O2S, CAS 247582-63-4

3-Bromo-2-chloro-5-(4-ethylpiperazin-1-ylsulfonyl)pyridine

CAS 247582-63-4C₁₁H₁₅BrClN₃O₂S

[5-(4-Methyl-piperazine-1-sulfonyl)-pyridin-2-yl]-hydrazine chemical structure, C10H17N5O2S, CAS 561012-68-8

[5-(4-Methyl-piperazine-1-sulfonyl)-pyridin-2-yl]-hydrazine

CAS 561012-68-8C₁₀H₁₇N₅O₂S

1-{4-[(6-Chloropyridin-3-yl)sulfonyl]piperazin-1-yl}ethan-1-one chemical structure, C11H14ClN3O3S, CAS 851788-00-6

1-{4-[(6-Chloropyridin-3-yl)sulfonyl]piperazin-1-yl}ethan-1-one

CAS 851788-00-6C₁₁H₁₄ClN₃O₃S

1-(6-Methoxypyridin-3-yl)sulfonyl-4-methylpiperazine chemical structure, C11H17N3O3S, CAS 7066-12-8

1-(6-Methoxypyridin-3-yl)sulfonyl-4-methylpiperazine

CAS 7066-12-8C₁₁H₁₇N₃O₃S

1-[(5-Bromo-6-chloropyridin-3-yl)sulfonyl]-4-methylpiperazine chemical structure, C10H13BrClN3O2S, CAS 247583-86-4

1-[(5-Bromo-6-chloropyridin-3-yl)sulfonyl]-4-methylpiperazine

CAS 247583-86-4C₁₀H₁₃BrClN₃O₂S

2-Ethoxy-5-[(4-ethylpiperazino)sulfonyl]nicotinic acid chemical structure, C14H21N3O5S, CAS 247582-73-6

2-Ethoxy-5-[(4-ethylpiperazino)sulfonyl]nicotinic acid

CAS 247582-73-6C₁₄H₂₁N₃O₅S

2-(4-[(6-Chloropyridin-3-yl)sulfonyl]piperazin-1-yl)ethan-1-ol chemical structure, C11H16ClN3O3S, CAS 622339-21-3

2-(4-[(6-Chloropyridin-3-yl)sulfonyl]piperazin-1-yl)ethan-1-ol

CAS 622339-21-3C₁₁H₁₆ClN₃O₃S

N,N-Diethyl-5-(4-methylpiperazine-1-sulfonyl)pyridin-2-amine chemical structure, C14H24N4O2S, CAS 7066-09-3

N,N-Diethyl-5-(4-methylpiperazine-1-sulfonyl)pyridin-2-amine

CAS 7066-09-3C₁₄H₂₄N₄O₂S

5-[(4-Methylpiperazinyl)sulfonyl]-2-pyridylamine chemical structure, C10H16N4O2S, CAS 627839-29-6

5-[(4-Methylpiperazinyl)sulfonyl]-2-pyridylamine

CAS 627839-29-6C₁₀H₁₆N₄O₂S

1-[(6-Ethoxy-3-pyridinyl)sulfonyl]-4-methylpiperazine chemical structure, C12H19N3O3S, CAS 627839-97-8

1-[(6-Ethoxy-3-pyridinyl)sulfonyl]-4-methylpiperazine

CAS 627839-97-8C₁₂H₁₉N₃O₃S

Ethyl 2-ethoxy-5-(4-ethyl-1-piperazinylsulfonyl)nicotinoate chemical structure, C16H25N3O5S, CAS 247582-68-9

Ethyl 2-ethoxy-5-(4-ethyl-1-piperazinylsulfonyl)nicotinoate

CAS 247582-68-9C₁₆H₂₅N₃O₅S

tert-Butyl 4-(6-chloropyridin-3-ylsulfonyl)piperazine-1-carboxylate chemical structure, C14H20ClN3O4S, CAS 848471-99-8

tert-Butyl 4-(6-chloropyridin-3-ylsulfonyl)piperazine-1-carboxylate

CAS 848471-99-8C₁₄H₂₀ClN₃O₄S

1-[(6-Chloropyridin-3-yl)sulfonyl]-4-(2-methoxyethyl)piperazine chemical structure, C12H18ClN3O3S, CAS 848472-03-7

1-[(6-Chloropyridin-3-yl)sulfonyl]-4-(2-methoxyethyl)piperazine

CAS 848472-03-7C₁₂H₁₈ClN₃O₃S

1-[(2-Chloropyridin-3-yl)sulfonyl]-4-methylpiperazine chemical structure, C10H14ClN3O2S, CAS 60597-73-1

1-[(2-Chloropyridin-3-yl)sulfonyl]-4-methylpiperazine

CAS 60597-73-1C₁₀H₁₄ClN₃O₂S

5-((4-Ethylpiperazin-1-yl)sulfonyl)-2-methoxynicotinic acid chemical structure, C13H19N3O5S, CAS 1437453-95-6

5-((4-Ethylpiperazin-1-yl)sulfonyl)-2-methoxynicotinic acid

CAS 1437453-95-6C₁₃H₁₉N₃O₅S

1-(6-Ethoxy-5-formyl-3-pyridylsulfonyl)-4-ethylpiperazine chemical structure, C14H21N3O4S, CAS 382631-60-9

1-(6-Ethoxy-5-formyl-3-pyridylsulfonyl)-4-ethylpiperazine

CAS 382631-60-9C₁₄H₂₁N₃O₄S

Ethyl 2-chloro-5-(4-ethyl-1-piperazinylsulfonyl)nicotinoate chemical structure, C14H20ClN3O4S, CAS 334708-08-6

Ethyl 2-chloro-5-(4-ethyl-1-piperazinylsulfonyl)nicotinoate

CAS 334708-08-6C₁₄H₂₀ClN₃O₄S

3-Bromo-2-ethoxy-5-(4-ethylpiperazin-1-ylsulphonyl)pyridine chemical structure, C13H20BrN3O3S, CAS 264920-27-6

3-Bromo-2-ethoxy-5-(4-ethylpiperazin-1-ylsulphonyl)pyridine

CAS 264920-27-6C₁₃H₂₀BrN₃O₃S

1-(Pyridine-3-sulfonyl)piperazine chemical structure, C9H13N3O2S, CAS 26103-50-4

1-(Pyridine-3-sulfonyl)piperazine

CAS 26103-50-4C₉H₁₃N₃O₂S

5-Bromo-3-(4-methylpiperazin-1-ylsulfonyl)pyridin-2-amine chemical structure, C10H15BrN4O2S, CAS 869008-95-7

5-Bromo-3-(4-methylpiperazin-1-ylsulfonyl)pyridin-2-amine

CAS 869008-95-7C₁₀H₁₅BrN₄O₂S

(2-[4-(Pyridin-3-ylsulfonyl)piperazin-1-yl]ethyl)amine chemical structure, C11H18N4O2S, CAS 1040631-59-1

(2-[4-(Pyridin-3-ylsulfonyl)piperazin-1-yl]ethyl)amine

CAS 1040631-59-1C₁₁H₁₈N₄O₂S

1-[(2-Hydrazinylpyridin-3-yl)sulfonyl]-4-methylpiperazine chemical structure, C10H17N5O2S, CAS 1154962-58-9

1-[(2-Hydrazinylpyridin-3-yl)sulfonyl]-4-methylpiperazine

CAS 1154962-58-9C₁₀H₁₇N₅O₂S