CompoundList
Sign in
Murcko scaffold

5-Oxo-1-phenyl-N-(pyridin-2-yl)pyrrolidine-3-carboxamide scaffold

46 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
46
With full pages
4
Scaffold SMILES

O=C(Nc1ccccn1)C1CC(=O)N(c2ccccc2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-Oxo-1-phenyl-N-(pyridin-2-yl)pyrrolidine-3-carboxamide page
Murcko scaffold O=C(Nc1ccccn1)C1CC(=O)N(c2ccccc2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 46 of 46 chemicals

1-(4-Fluorophenyl)-N-(3-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide chemical structure, C17H16FN3O2, CAS 361463-70-9
1-(4-Fluorophenyl)-N-(3-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide
CAS 361463-70-9C17H16FN3O2
1-(4-Bromophenyl)-5-oxo-N-(pyridin-2-yl)pyrrolidine-3-carboxamide chemical structure, C16H14BrN3O2, CAS 303066-83-3
1-(4-Bromophenyl)-5-oxo-N-(pyridin-2-yl)pyrrolidine-3-carboxamide
CAS 303066-83-3C16H14BrN3O2
1-(4-Bromophenyl)-N-(6-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide chemical structure, C17H16BrN3O2, CAS 6059-50-3
1-(4-Bromophenyl)-N-(6-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide
CAS 6059-50-3C17H16BrN3O2
1-(4-Chlorophenyl)-N-(6-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide chemical structure, C17H16ClN3O2, CAS 341951-56-2
1-(4-Chlorophenyl)-N-(6-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide
CAS 341951-56-2C17H16ClN3O2
1-(4-Methoxyphenyl)-N-(4-methyl-2-pyridinyl)-5-oxo-3-pyrrolidinecarboxamide chemical structure, C18H19N3O3, CAS 309734-04-1
1-(4-Methoxyphenyl)-N-(4-methyl-2-pyridinyl)-5-oxo-3-pyrrolidinecarboxamide
CAS 309734-04-1C18H19N3O3
1-(4-Butoxyphenyl)-N-(3-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide chemical structure, C21H25N3O3, CAS 346456-88-0
1-(4-Butoxyphenyl)-N-(3-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide
CAS 346456-88-0C21H25N3O3
1-(4-Ethoxyphenyl)-N-(4-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide chemical structure, C19H21N3O3, CAS 330833-23-3
1-(4-Ethoxyphenyl)-N-(4-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide
CAS 330833-23-3C19H21N3O3
1-(3,4-Dimethylphenyl)-N-(4-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide chemical structure, C19H21N3O2, CAS 592477-41-3
1-(3,4-Dimethylphenyl)-N-(4-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide
CAS 592477-41-3C19H21N3O2
1-(4-Bromophenyl)-N-(3-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide chemical structure, C17H16BrN3O2, CAS 510724-38-6
1-(4-Bromophenyl)-N-(3-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide
CAS 510724-38-6C17H16BrN3O2
5-Oxo-1-phenyl-N-(pyridin-2-yl)pyrrolidine-3-carboxamide chemical structure, C16H15N3O2, CAS 332065-13-1
5-Oxo-1-phenyl-N-(pyridin-2-yl)pyrrolidine-3-carboxamide
CAS 332065-13-1C16H15N3O2
1-(4-Chlorophenyl)-N-(4-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide chemical structure, C17H16ClN3O2, CAS 381197-74-6
1-(4-Chlorophenyl)-N-(4-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide
CAS 381197-74-6C17H16ClN3O2
1-(4-Ethoxyphenyl)-N-(6-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide chemical structure, C19H21N3O3, CAS 361997-35-5
1-(4-Ethoxyphenyl)-N-(6-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide
CAS 361997-35-5C19H21N3O3
1-(3,4-Dimethylphenyl)-N-(6-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide chemical structure, C19H21N3O2, CAS 640691-22-1
1-(3,4-Dimethylphenyl)-N-(6-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide
CAS 640691-22-1C19H21N3O2
N-(5-Chloropyridin-2-yl)-1-(4-methylphenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C17H16ClN3O2, CAS 825597-60-2
N-(5-Chloropyridin-2-yl)-1-(4-methylphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 825597-60-2C17H16ClN3O2
1-(4-Fluorophenyl)-N-(6-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide chemical structure, C17H16FN3O2, CAS 643731-93-5
1-(4-Fluorophenyl)-N-(6-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide
CAS 643731-93-5C17H16FN3O2
N-(5-Chloropyridin-2-yl)-1-(4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C17H16ClN3O3, CAS 878426-20-1
N-(5-Chloropyridin-2-yl)-1-(4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 878426-20-1C17H16ClN3O3
N-(5-Chloropyridin-2-yl)-1-(4-fluorophenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C16H13ClFN3O2, CAS 878430-23-0
N-(5-Chloropyridin-2-yl)-1-(4-fluorophenyl)-5-oxopyrrolidine-3-carboxamide
CAS 878430-23-0C16H13ClFN3O2
N-(5-Chloropyridin-2-yl)-1-(2,3-dimethylphenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C18H18ClN3O2, CAS 887680-08-2
N-(5-Chloropyridin-2-yl)-1-(2,3-dimethylphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 887680-08-2C18H18ClN3O2
N-(5-Chloropyridin-2-yl)-1-(4-ethoxyphenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C18H18ClN3O3, CAS 878431-55-1
N-(5-Chloropyridin-2-yl)-1-(4-ethoxyphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 878431-55-1C18H18ClN3O3
N-(5-Chloropyridin-2-yl)-5-oxo-1-phenylpyrrolidine-3-carboxamide chemical structure, C16H14ClN3O2, CAS 879595-44-5
N-(5-Chloropyridin-2-yl)-5-oxo-1-phenylpyrrolidine-3-carboxamide
CAS 879595-44-5C16H14ClN3O2
1-(4-Chlorophenyl)-N-(5-chloropyridin-2-yl)-5-oxopyrrolidine-3-carboxamide chemical structure, C16H13Cl2N3O2, CAS 878442-29-6
1-(4-Chlorophenyl)-N-(5-chloropyridin-2-yl)-5-oxopyrrolidine-3-carboxamide
CAS 878442-29-6C16H13Cl2N3O2
1-(2-Ethoxyphenyl)-5-oxo-N-(pyridin-2-yl)pyrrolidine-3-carboxamide chemical structure, C18H19N3O3, CAS 873569-63-2
1-(2-Ethoxyphenyl)-5-oxo-N-(pyridin-2-yl)pyrrolidine-3-carboxamide
CAS 873569-63-2C18H19N3O3
N-(5-Chloropyridin-2-yl)-1-(3-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C17H16ClN3O3, CAS 924965-21-9
N-(5-Chloropyridin-2-yl)-1-(3-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 924965-21-9C17H16ClN3O3
1-(2,4-Dimethoxyphenyl)-5-oxo-N-(pyridin-2-yl)pyrrolidine-3-carboxamide chemical structure, C18H19N3O4, CAS 924970-18-3
1-(2,4-Dimethoxyphenyl)-5-oxo-N-(pyridin-2-yl)pyrrolidine-3-carboxamide
CAS 924970-18-3C18H19N3O4