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Murcko scaffold

3-(Pyridin-2-yl)cyclobutan-1-one scaffold

47 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 11
Chemicals: 47
With full pages: 4

Scaffold SMILES

O=C1CC(c2ccccn2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 3-(Pyridin-2-yl)cyclobutan-1-one page

Murcko scaffold O=C1CC(c2ccccn2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 47 of 47 chemicals

3-(Pyridin-2-yl)cyclobutan-1-one chemical structure, C9H9NO, CAS 1080636-50-5

3-(Pyridin-2-yl)cyclobutan-1-one

CAS 1080636-50-5C₉H₉NO

1-(3-Fluoropyridin-2-yl)-3-oxocyclobutane-1-carbonitrile chemical structure, C10H7FN2O, CAS 1344145-36-3

1-(3-Fluoropyridin-2-yl)-3-oxocyclobutane-1-carbonitrile

CAS 1344145-36-3C₁₀H₇FN₂O

3-Oxo-1-(pyridin-2-yl)cyclobutane-1-carbonitrile chemical structure, C10H8N2O, CAS 1522153-71-4

3-Oxo-1-(pyridin-2-yl)cyclobutane-1-carbonitrile

CAS 1522153-71-4C₁₀H₈N₂O

3-Oxo-1-(pyridin-2-yl)cyclobutane-1-carboxylic acid chemical structure, C10H9NO3, CAS 1934915-58-8

3-Oxo-1-(pyridin-2-yl)cyclobutane-1-carboxylic acid

CAS 1934915-58-8C₁₀H₉NO₃

1-(6-Bromopyridin-2-yl)-3-oxocyclobutane-1-carbonitrile chemical structure, C10H7BrN2O, CAS 2229105-45-5

1-(6-Bromopyridin-2-yl)-3-oxocyclobutane-1-carbonitrile

CAS 2229105-45-5C₁₀H₇BrN₂O

1-(6-Chloropyridin-2-yl)-3-oxocyclobutane-1-carbonitrile chemical structure, C10H7ClN2O, CAS 2229459-62-3

1-(6-Chloropyridin-2-yl)-3-oxocyclobutane-1-carbonitrile

CAS 2229459-62-3C₁₀H₇ClN₂O

1-(6-Methoxypyridin-2-yl)-3-oxocyclobutane-1-carbonitrile chemical structure, C11H10N2O2, CAS 2228926-60-9

1-(6-Methoxypyridin-2-yl)-3-oxocyclobutane-1-carbonitrile

CAS 2228926-60-9C₁₁H₁₀N₂O₂

1-(5-Fluoropyridin-2-yl)-3-oxocyclobutane-1-carbonitrile chemical structure, C10H7FN2O, CAS 2228342-56-9

1-(5-Fluoropyridin-2-yl)-3-oxocyclobutane-1-carbonitrile

CAS 2228342-56-9C₁₀H₇FN₂O

1-(5-Chloropyridin-2-yl)-3-oxocyclobutane-1-carbonitrile chemical structure, C10H7ClN2O, CAS 2228273-55-8

1-(5-Chloropyridin-2-yl)-3-oxocyclobutane-1-carbonitrile

CAS 2228273-55-8C₁₀H₇ClN₂O

1-(5-Bromopyridin-2-yl)-3-oxocyclobutane-1-carbonitrile chemical structure, C10H7BrN2O, CAS 2228201-31-6

1-(5-Bromopyridin-2-yl)-3-oxocyclobutane-1-carbonitrile

CAS 2228201-31-6C₁₀H₇BrN₂O

3-Oxo-1-[5-(trifluoromethyl)pyridin-2-yl]cyclobutane-1-carbonitrile chemical structure, C11H7F3N2O, CAS 2229277-57-8

3-Oxo-1-[5-(trifluoromethyl)pyridin-2-yl]cyclobutane-1-carbonitrile

CAS 2229277-57-8C₁₁H₇F₃N₂O

1-(4-Fluoropyridin-2-yl)-3-oxocyclobutane-1-carbonitrile chemical structure, C10H7FN2O, CAS 2228467-18-1

1-(4-Fluoropyridin-2-yl)-3-oxocyclobutane-1-carbonitrile

CAS 2228467-18-1C₁₀H₇FN₂O

1-(4-Methoxypyridin-2-yl)-3-oxocyclobutane-1-carbonitrile chemical structure, C11H10N2O2, CAS 2229415-52-3

1-(4-Methoxypyridin-2-yl)-3-oxocyclobutane-1-carbonitrile

CAS 2229415-52-3C₁₁H₁₀N₂O₂

1-(3-Bromopyridin-2-yl)-3-oxocyclobutane-1-carbonitrile chemical structure, C10H7BrN2O, CAS 2228878-62-2

1-(3-Bromopyridin-2-yl)-3-oxocyclobutane-1-carbonitrile

CAS 2228878-62-2C₁₀H₇BrN₂O

1-(3-Methoxypyridin-2-yl)-3-oxocyclobutane-1-carbonitrile chemical structure, C11H10N2O2, CAS 2228415-92-5

1-(3-Methoxypyridin-2-yl)-3-oxocyclobutane-1-carbonitrile

CAS 2228415-92-5C₁₁H₁₀N₂O₂

3-Oxo-1-[3-(trifluoromethyl)pyridin-2-yl]cyclobutane-1-carbonitrile chemical structure, C11H7F3N2O, CAS 2228277-21-0

3-Oxo-1-[3-(trifluoromethyl)pyridin-2-yl]cyclobutane-1-carbonitrile

CAS 2228277-21-0C₁₁H₇F₃N₂O

3-(5-Bromopyridin-2-yl)cyclobutan-1-one chemical structure, C9H8BrNO, CAS 2002705-28-2

3-(5-Bromopyridin-2-yl)cyclobutan-1-one

CAS 2002705-28-2C₉H₈BrNO

3-(3-Bromopyridin-2-yl)cyclobutan-1-one chemical structure, C9H8BrNO, CAS 2356503-08-5

3-(3-Bromopyridin-2-yl)cyclobutan-1-one

CAS 2356503-08-5C₉H₈BrNO

3-(4-Bromopyridin-2-yl)cyclobutan-1-one chemical structure, C9H8BrNO, CAS 2648962-22-3

3-(4-Bromopyridin-2-yl)cyclobutan-1-one

CAS 2648962-22-3C₉H₈BrNO

3-Pyridin-2-yl-cyclobutanone hydrochloride chemical structure, C9H10ClNO, CAS 2760889-70-9

3-Pyridin-2-yl-cyclobutanone hydrochloride

CAS 2760889-70-9C₉H₁₀ClNO

1-(5-Methylpyridin-2-yl)-3-oxocyclobutane-1-carboxylic acid chemical structure, C11H11NO3, CAS 2228656-47-9

1-(5-Methylpyridin-2-yl)-3-oxocyclobutane-1-carboxylic acid

CAS 2228656-47-9C₁₁H₁₁NO₃

1-(4-Fluoropyridin-2-yl)-3-oxocyclobutane-1-carboxylic acid chemical structure, C10H8FNO3, CAS 2228804-34-8

1-(4-Fluoropyridin-2-yl)-3-oxocyclobutane-1-carboxylic acid

CAS 2228804-34-8C₁₀H₈FNO₃

1-(3-Bromopyridin-2-yl)-3-oxocyclobutane-1-carboxylic acid chemical structure, C10H8BrNO3, CAS 2228870-63-9

1-(3-Bromopyridin-2-yl)-3-oxocyclobutane-1-carboxylic acid

CAS 2228870-63-9C₁₀H₈BrNO₃

1-(5-Nitropyridin-2-yl)-3-oxocyclobutane-1-carbonitrile chemical structure, C10H7N3O3, CAS 2228476-28-4

1-(5-Nitropyridin-2-yl)-3-oxocyclobutane-1-carbonitrile

CAS 2228476-28-4C₁₀H₇N₃O₃