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Murcko scaffold

2-(Phenylsulfonyl)-N-(1,3,4-thiadiazol-2-yl)acetamide scaffold

17 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
17
With full pages
4
Scaffold SMILES

O=C(CS(=O)(=O)c1ccccc1)Nc1nncs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Phenylsulfonyl)-N-(1,3,4-thiadiazol-2-yl)acetamide page
Murcko scaffold O=C(CS(=O)(=O)c1ccccc1)Nc1nncs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

2-(Phenylsulfonyl)-N-(1,3,4-thiadiazol-2-yl)acetamide chemical structure, C10H9N3O3S2, CAS 725706-98-9
2-(Phenylsulfonyl)-N-(1,3,4-thiadiazol-2-yl)acetamide
CAS 725706-98-9C10H9N3O3S2
2-[(4-Methoxyphenyl)sulfonyl]-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C12H10F3N3O4S2, CAS 339014-02-7
2-[(4-Methoxyphenyl)sulfonyl]-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 339014-02-7C12H10F3N3O4S2
2-[(4-Bromophenyl)sulfonyl]-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C11H7BrF3N3O3S2, CAS 339014-03-8
2-[(4-Bromophenyl)sulfonyl]-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 339014-03-8C11H7BrF3N3O3S2
2-[(3-Chlorophenyl)sulfonyl]-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C11H7ClF3N3O3S2, CAS 339014-04-9
2-[(3-Chlorophenyl)sulfonyl]-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 339014-04-9C11H7ClF3N3O3S2
2-[(4-Methylphenyl)sulfonyl]-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C12H10F3N3O3S2, CAS 339014-06-1
2-[(4-Methylphenyl)sulfonyl]-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 339014-06-1C12H10F3N3O3S2
2-(Benzenesulfonyl)-N-(5-pentan-2-yl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C15H19N3O3S2, CAS 838851-13-1
2-(Benzenesulfonyl)-N-(5-pentan-2-yl-1,3,4-thiadiazol-2-yl)acetamide
CAS 838851-13-1C15H19N3O3S2
2-(Benzenesulfonyl)-N-[5-(2-methoxyethylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C13H15N3O4S3, CAS 876884-71-8
2-(Benzenesulfonyl)-N-[5-(2-methoxyethylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 876884-71-8C13H15N3O4S3
2-(Benzenesulfonyl)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C12H13N3O3S2, CAS 838900-10-0
2-(Benzenesulfonyl)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 838900-10-0C12H13N3O3S2
2-(Benzenesulfonyl)-N-[5-(2-ethoxyethyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C14H17N3O4S2, CAS 838904-23-7
2-(Benzenesulfonyl)-N-[5-(2-ethoxyethyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 838904-23-7C14H17N3O4S2
2-(Benzenesulfonyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C11H8F3N3O3S2, CAS 876884-34-3
2-(Benzenesulfonyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 876884-34-3C11H8F3N3O3S2
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-[(4-methylphenyl)sulfonyl]acetamide chemical structure, C13H15N3O3S2, CAS 878427-41-9
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-[(4-methylphenyl)sulfonyl]acetamide
CAS 878427-41-9C13H15N3O3S2
2-(4-Methylphenyl)sulfonyl-N-(5-propyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C14H17N3O3S2, CAS 878427-47-5
2-(4-Methylphenyl)sulfonyl-N-(5-propyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 878427-47-5C14H17N3O3S2
N-[5-(2-Ethoxyethyl)-1,3,4-thiadiazol-2-yl]-2-(4-methylphenyl)sulfonylacetamide chemical structure, C15H19N3O4S2, CAS 878427-59-9
N-[5-(2-Ethoxyethyl)-1,3,4-thiadiazol-2-yl]-2-(4-methylphenyl)sulfonylacetamide
CAS 878427-59-9C15H19N3O4S2
N-[5-(2-Methoxyethylsulfanyl)-1,3,4-thiadiazol-2-yl]-2-(4-methylphenyl)sulfonylacetamide chemical structure, C14H17N3O4S3, CAS 878427-53-3
N-[5-(2-Methoxyethylsulfanyl)-1,3,4-thiadiazol-2-yl]-2-(4-methylphenyl)sulfonylacetamide
CAS 878427-53-3C14H17N3O4S3
N-[5-(Methylsulfanyl)-1,3,4-thiadiazol-2-yl]-2-(phenylsulfonyl)acetamide chemical structure, C11H11N3O3S3, CAS 919471-38-8
N-[5-(Methylsulfanyl)-1,3,4-thiadiazol-2-yl]-2-(phenylsulfonyl)acetamide
CAS 919471-38-8C11H11N3O3S3
2-[(4-Chlorophenyl)sulfonyl]-N-(1,3,4-thiadiazol-2-yl)acetamide chemical structure, C10H8ClN3O3S2, CAS 1049126-25-1
2-[(4-Chlorophenyl)sulfonyl]-N-(1,3,4-thiadiazol-2-yl)acetamide
CAS 1049126-25-1C10H8ClN3O3S2
2-[(4-Chlorophenyl)sulfonyl]-N-[(2E)-5-(methylsulfanyl)-1,3,4-thiadiazol-2(3H)-ylidene]acetamide chemical structure, C11H10ClN3O3S3, CAS 1049116-76-8
2-[(4-Chlorophenyl)sulfonyl]-N-[(2E)-5-(methylsulfanyl)-1,3,4-thiadiazol-2(3H)-ylidene]acetamide
CAS 1049116-76-8C11H10ClN3O3S3