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Murcko scaffold

1-(2-Tetrahydropyranyl)-1H-pyrazole scaffold

214 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
214
With full pages
17
Scaffold SMILES

c1cnn(C2CCCCO2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(2-Tetrahydropyranyl)-1H-pyrazole page
Murcko scaffold c1cnn(C2CCCCO2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 214 chemicals

N-(5-Methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-3-yl)acetamide chemical structure, C11H17N3O2, CAS 1028362-83-5
N-(5-Methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-3-yl)acetamide
CAS 1028362-83-5C11H17N3O2
3-Methyl-1-tetrahydro-2H-pyran-2-yl-1H-pyrazole-4-carboxylic acid chemical structure, C10H14N2O3, CAS 897657-11-3
3-Methyl-1-tetrahydro-2H-pyran-2-yl-1H-pyrazole-4-carboxylic acid
CAS 897657-11-3C10H14N2O3
1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole-4-carboxylic acid chemical structure, C9H12N2O3, CAS 848818-59-7
1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole-4-carboxylic acid
CAS 848818-59-7C9H12N2O3
5-Methyl-1-(oxan-2-yl)pyrazole chemical structure, C9H14N2O, CAS 1633661-59-2
5-Methyl-1-(oxan-2-yl)pyrazole
CAS 1633661-59-2C9H14N2O
3-Iodo-1-(oxan-2-yl)pyrazole chemical structure, C8H11IN2O, CAS 1305323-24-3
3-Iodo-1-(oxan-2-yl)pyrazole
CAS 1305323-24-3C8H11IN2O
4-Bromo-5-methyl-2-(oxan-2-yl)pyrazole-3-carbaldehyde chemical structure, C10H13BrN2O2, CAS 1373232-52-0
4-Bromo-5-methyl-2-(oxan-2-yl)pyrazole-3-carbaldehyde
CAS 1373232-52-0C10H13BrN2O2
Potassium 1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole-4-trifluoroborate chemical structure, C8H11BF3KN2O, CAS 1423013-22-2
Potassium 1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole-4-trifluoroborate
CAS 1423013-22-2C8H11BF3KN2O
4-Bromo-1-(oxan-2-yl)-3-(trifluoromethyl)-1H-pyrazole chemical structure, C9H10BrF3N2O, CAS 1260667-53-5
4-Bromo-1-(oxan-2-yl)-3-(trifluoromethyl)-1H-pyrazole
CAS 1260667-53-5C9H10BrF3N2O
5-Chloro-3-methyl-1-tetrahydro-2H-pyran-2-YL-1H-pyrazole-4-carbaldehyde chemical structure, C10H13ClN2O2, CAS 1393576-03-8
5-Chloro-3-methyl-1-tetrahydro-2H-pyran-2-YL-1H-pyrazole-4-carbaldehyde
CAS 1393576-03-8C10H13ClN2O2
1-(Tetrahydro-2H-pyran-2-yl)-3-(trifluoromethyl)-1H-pyrazole-5-carbaldehyde chemical structure, C10H11F3N2O2, CAS 1437794-28-9
1-(Tetrahydro-2H-pyran-2-yl)-3-(trifluoromethyl)-1H-pyrazole-5-carbaldehyde
CAS 1437794-28-9C10H11F3N2O2
Methyl 5-bromo-1-(oxan-2-yl)-1H-pyrazole-4-carboxylate chemical structure, C10H13BrN2O3, CAS 1434142-09-2
Methyl 5-bromo-1-(oxan-2-yl)-1H-pyrazole-4-carboxylate
CAS 1434142-09-2C10H13BrN2O3
4-Iodo-1-(oxan-2-yl)pyrazole-5-carbaldehyde chemical structure, C9H11IN2O2, CAS 1400644-65-6
4-Iodo-1-(oxan-2-yl)pyrazole-5-carbaldehyde
CAS 1400644-65-6C9H11IN2O2
4,5-Diiodo-1-(oxan-2-yl)pyrazole chemical structure, C8H10I2N2O, CAS 1403483-65-7
4,5-Diiodo-1-(oxan-2-yl)pyrazole
CAS 1403483-65-7C8H10I2N2O
5-Bromo-4-nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole chemical structure, C8H10BrN3O3, CAS 1429309-54-5
5-Bromo-4-nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole
CAS 1429309-54-5C8H10BrN3O3
1-[1-(Oxan-2-yl)-1H-pyrazol-5-yl]methanamine chemical structure, C9H15N3O, CAS 1820642-31-6
1-[1-(Oxan-2-yl)-1H-pyrazol-5-yl]methanamine
CAS 1820642-31-6C9H15N3O
1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole-3-carbaldehyde chemical structure, C9H12N2O2, CAS 1809564-49-5
1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole-3-carbaldehyde
CAS 1809564-49-5C9H12N2O2
1-(Oxan-2-yl)-1H-pyrazol-4-amine chemical structure, C8H13N3O, CAS 1216165-35-3
1-(Oxan-2-yl)-1H-pyrazol-4-amine
CAS 1216165-35-3C8H13N3O
1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole-4-carbaldehyde chemical structure, C9H12N2O2, CAS 1197943-43-3
1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole-4-carbaldehyde
CAS 1197943-43-3C9H12N2O2
3-Methyl-4-nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole chemical structure, C9H13N3O3, CAS 191847-03-7
3-Methyl-4-nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole
CAS 191847-03-7C9H13N3O3
1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole-4-carbonyl fluoride chemical structure, C9H11FN2O2, CAS 848818-60-0
1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole-4-carbonyl fluoride
CAS 848818-60-0C9H11FN2O2
Ethyl 3-{[(methylsulfonyl)oxy]methyl}-1-tetrahydro-2H-pyran-2-yl-1H-pyrazole-5-carboxylate chemical structure, C13H20N2O6S, CAS 847139-29-1
Ethyl 3-{[(methylsulfonyl)oxy]methyl}-1-tetrahydro-2H-pyran-2-yl-1H-pyrazole-5-carboxylate
CAS 847139-29-1C13H20N2O6S
1-(Oxan-2-yl)-1H-pyrazole-3-carboxylic acid chemical structure, C9H12N2O3, CAS 2122066-46-8
1-(Oxan-2-yl)-1H-pyrazole-3-carboxylic acid
CAS 2122066-46-8C9H12N2O3
Methyl 1-(Tetrahydro-2H-pyran-2-yl)pyrazole-3-carboxylate chemical structure, C10H14N2O3, CAS 1823361-26-7
Methyl 1-(Tetrahydro-2H-pyran-2-yl)pyrazole-3-carboxylate
CAS 1823361-26-7C10H14N2O3
1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole-4-carbonitrile chemical structure, C9H11N3O, CAS 1448317-12-1
1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole-4-carbonitrile
CAS 1448317-12-1C9H11N3O