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Murcko scaffold

1-(2-Tetrahydropyranyl)-1H-pyrazole scaffold

214 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
214
With full pages
17
Scaffold SMILES

c1cnn(C2CCCCO2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(2-Tetrahydropyranyl)-1H-pyrazole page
Murcko scaffold c1cnn(C2CCCCO2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 193 to 214 of 214 chemicals

3-((Methylthio)methyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole chemical structure, C10H16N2OS, CAS 2566440-16-0
3-((Methylthio)methyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole
CAS 2566440-16-0C10H16N2OS
Methyl 1-tetrahydropyran-2-ylpyrazole-4-carboxylate chemical structure, C10H14N2O3, CAS 2940938-84-9
Methyl 1-tetrahydropyran-2-ylpyrazole-4-carboxylate
CAS 2940938-84-9C10H14N2O3
Ethyl 4-iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole-3-carboxylate chemical structure, C11H15IN2O3, CAS 179692-10-5
Ethyl 4-iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole-3-carboxylate
CAS 179692-10-5C11H15IN2O3
3-Bromo-4-nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole chemical structure, C8H10BrN3O3, CAS 2924300-96-7
3-Bromo-4-nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole
CAS 2924300-96-7C8H10BrN3O3
tert-Butyl N-(4-fluoro-2-tetrahydropyran-2-yl-pyrazol-3-yl)carbamate chemical structure, C13H20FN3O3, CAS 2940944-63-6
tert-Butyl N-(4-fluoro-2-tetrahydropyran-2-yl-pyrazol-3-yl)carbamate
CAS 2940944-63-6C13H20FN3O3
4-Iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole-3-carboxylic acid chemical structure, C9H11IN2O3, CAS 2454172-99-5
4-Iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole-3-carboxylic acid
CAS 2454172-99-5C9H11IN2O3
Methyl 3-nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole-5-carboxylate chemical structure, C10H13N3O5, CAS 2706585-22-8
Methyl 3-nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole-5-carboxylate
CAS 2706585-22-8C10H13N3O5
1-(Oxan-2-yl)-5-(propan-2-yl)-1H-pyrazol-3-amine chemical structure, C11H19N3O, CAS 2706585-71-7
1-(Oxan-2-yl)-5-(propan-2-yl)-1H-pyrazol-3-amine
CAS 2706585-71-7C11H19N3O
5-Isobutyl-1-tetrahydropyran-2-yl-pyrazol-3-amine chemical structure, C12H21N3O, CAS 2706585-18-2
5-Isobutyl-1-tetrahydropyran-2-yl-pyrazol-3-amine
CAS 2706585-18-2C12H21N3O
5-(Methoxymethyl)-1-tetrahydropyran-2-yl-pyrazol-3-amine chemical structure, C10H17N3O2, CAS 2706585-25-1
5-(Methoxymethyl)-1-tetrahydropyran-2-yl-pyrazol-3-amine
CAS 2706585-25-1C10H17N3O2
Lithium salt, 2-tetrahydropyran-2-ylpyrazole-3-sulfinic acid chemical structure, C8H13LiN2O3S
Lithium salt, 2-tetrahydropyran-2-ylpyrazole-3-sulfinic acid
C8H13LiN2O3S
2-(1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazol-3-yl)acetic acid chemical structure, C10H14N2O3, CAS 2917695-44-2
2-(1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazol-3-yl)acetic acid
CAS 2917695-44-2C10H14N2O3
2-Methyl-1-(1-tetrahydropyran-2-ylpyrazol-3-yl)propan-2-ol chemical structure, C12H20N2O2, CAS 2940941-97-7
2-Methyl-1-(1-tetrahydropyran-2-ylpyrazol-3-yl)propan-2-ol
CAS 2940941-97-7C12H20N2O2
Methyl 4-ethynyl-1-(oxan-2-yl)-1H-pyrazole-3-carboxylate chemical structure, C12H14N2O3, CAS 2932439-49-9
Methyl 4-ethynyl-1-(oxan-2-yl)-1H-pyrazole-3-carboxylate
CAS 2932439-49-9C12H14N2O3
3-[1-(Oxan-2-yl)-1H-pyrazol-4-yl]prop-2-ynoic acid chemical structure, C11H12N2O3, CAS 2582135-83-7
3-[1-(Oxan-2-yl)-1H-pyrazol-4-yl]prop-2-ynoic acid
CAS 2582135-83-7C11H12N2O3
5-tert-Butyl-1-(oxan-2-yl)pyrazol-3-amine chemical structure, C12H21N3O, CAS 3028141-46-7
5-tert-Butyl-1-(oxan-2-yl)pyrazol-3-amine
CAS 3028141-46-7C12H21N3O
4-Chloro-1-(oxan-2-yl)-1H-pyrazol-3-amine chemical structure, C8H12ClN3O, CAS 2166815-25-2
4-Chloro-1-(oxan-2-yl)-1H-pyrazol-3-amine
CAS 2166815-25-2C8H12ClN3O
4-Methyl-1-(oxan-2-yl)pyrazol-3-amine chemical structure, C9H15N3O, CAS 2283562-15-0
4-Methyl-1-(oxan-2-yl)pyrazol-3-amine
CAS 2283562-15-0C9H15N3O
Diethyl 2-(1-tetrahydropyran-2-ylpyrazol-3-yl)propanedioate chemical structure, C15H22N2O5, CAS 2411641-19-3
Diethyl 2-(1-tetrahydropyran-2-ylpyrazol-3-yl)propanedioate
CAS 2411641-19-3C15H22N2O5
[1-(Oxan-2-yl)-1H-pyrazol-4-yl]methanesulfonyl fluoride chemical structure, C9H13FN2O3S, CAS 3059238-21-7
[1-(Oxan-2-yl)-1H-pyrazol-4-yl]methanesulfonyl fluoride
CAS 3059238-21-7C9H13FN2O3S
1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole-5-sulfinic acid, lithium salt chemical structure, C8H12LiN2O3S
1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole-5-sulfinic acid, lithium salt
C8H12LiN2O3S
Methyl 3-(((tert-butyldimethylsilyl)oxy)methyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole-5-carboxylate chemical structure, C17H30N2O4Si, CAS 2758240-25-2
Methyl 3-(((tert-butyldimethylsilyl)oxy)methyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole-5-carboxylate
CAS 2758240-25-2C17H30N2O4Si