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Murcko scaffold

1-(2-Tetrahydropyranyl)-1H-pyrazole scaffold

214 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
214
With full pages
17
Scaffold SMILES

c1cnn(C2CCCCO2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(2-Tetrahydropyranyl)-1H-pyrazole page
Murcko scaffold c1cnn(C2CCCCO2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 192 of 214 chemicals

1-(5-Nitro-2-tetrahydropyran-2-yl-pyrazol-3-yl)ethanone chemical structure, C10H13N3O4, CAS 2708292-32-2
1-(5-Nitro-2-tetrahydropyran-2-yl-pyrazol-3-yl)ethanone
CAS 2708292-32-2C10H13N3O4
3,5-Dichloro-4-nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole chemical structure, C8H9Cl2N3O3, CAS 2265202-20-6
3,5-Dichloro-4-nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole
CAS 2265202-20-6C8H9Cl2N3O3
3,5-Dichloro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-4-amine chemical structure, C8H11Cl2N3O, CAS 2450343-45-8
3,5-Dichloro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-4-amine
CAS 2450343-45-8C8H11Cl2N3O
3-Chloro-4-nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole chemical structure, C8H10ClN3O3, CAS 2450343-44-7
3-Chloro-4-nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole
CAS 2450343-44-7C8H10ClN3O3
Methyl 4-iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole-3-carboxylate chemical structure, C10H13IN2O3, CAS 191847-01-5
Methyl 4-iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole-3-carboxylate
CAS 191847-01-5C10H13IN2O3
Methyl 4-bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole-3-carboxylate chemical structure, C10H13BrN2O3, CAS 190263-30-0
Methyl 4-bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole-3-carboxylate
CAS 190263-30-0C10H13BrN2O3
[1-(Tetrahydro-pyran-2-yl)-1H-pyrazol-4-yloxy]-acetic acid chemical structure, C10H14N2O4, CAS 2740354-15-6
[1-(Tetrahydro-pyran-2-yl)-1H-pyrazol-4-yloxy]-acetic acid
CAS 2740354-15-6C10H14N2O4
3-((1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazol-4-yl)oxy)propan-1-ol chemical structure, C11H18N2O3, CAS 2741613-73-8
3-((1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazol-4-yl)oxy)propan-1-ol
CAS 2741613-73-8C11H18N2O3
3_(Ethoxycarbonyl)_1_(tetrahydro_2H_pyran_2_yl)_1H_pyrazole_4_carboxylic acid chemical structure, C12H16N2O5, CAS 2454173-09-0
3_(Ethoxycarbonyl)_1_(tetrahydro_2H_pyran_2_yl)_1H_pyrazole_4_carboxylic acid
CAS 2454173-09-0C12H16N2O5
3,5-Dibromo-4-nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole chemical structure, C8H9Br2N3O3, CAS 2454173-17-0
3,5-Dibromo-4-nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole
CAS 2454173-17-0C8H9Br2N3O3
3-Bromo-5-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole chemical structure, C9H13BrN2O, CAS 2925214-53-3
3-Bromo-5-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole
CAS 2925214-53-3C9H13BrN2O
5-(Chloromethyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole chemical structure, C9H13ClN2O, CAS 2252267-64-2
5-(Chloromethyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole
CAS 2252267-64-2C9H13ClN2O
(4-Bromo-5-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-3-yl)methanol chemical structure, C10H15BrN2O2, CAS 2569617-48-5
(4-Bromo-5-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-3-yl)methanol
CAS 2569617-48-5C10H15BrN2O2
4-Iodo-1-(tetrahydro-2H-pyran-2-yl)-5-(trimethylsilyl)-1H-pyrazole chemical structure, C11H19IN2OSi, CAS 1936476-08-2
4-Iodo-1-(tetrahydro-2H-pyran-2-yl)-5-(trimethylsilyl)-1H-pyrazole
CAS 1936476-08-2C11H19IN2OSi
3-Chloro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole chemical structure, C8H11ClN2O, CAS 2306261-33-4
3-Chloro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole
CAS 2306261-33-4C8H11ClN2O
1-(Oxan-2-yl)-1H-pyrazole-4-carboximidamide, acetic acid chemical structure, C11H18N4O3, CAS 2648942-05-4
1-(Oxan-2-yl)-1H-pyrazole-4-carboximidamide, acetic acid
CAS 2648942-05-4C11H18N4O3
1-(Oxan-2-yl)-1H-pyrazole-4-carboximidamide chemical structure, C9H14N4O, CAS 2648942-04-3
1-(Oxan-2-yl)-1H-pyrazole-4-carboximidamide
CAS 2648942-04-3C9H14N4O
Imino(methyl)[1-(oxan-2-yl)-1H-pyrazol-4-yl]-lambda6-sulfanone chemical structure, C9H15N3O2S, CAS 2624137-26-2
Imino(methyl)[1-(oxan-2-yl)-1H-pyrazol-4-yl]-lambda6-sulfanone
CAS 2624137-26-2C9H15N3O2S
4-Methylpyrazole-N-glucosiduronic acid chemical structure, C10H14N2O6, CAS 37718-09-5
4-Methylpyrazole-N-glucosiduronic acid
CAS 37718-09-5C10H14N2O6
Ethyl 4-amino-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole-3-carboxylate chemical structure, C11H17N3O3, CAS 2394877-04-2
Ethyl 4-amino-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole-3-carboxylate
CAS 2394877-04-2C11H17N3O3
3-Bromo-5-(difluoromethyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole chemical structure, C9H11BrF2N2O, CAS 2653202-22-1
3-Bromo-5-(difluoromethyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole
CAS 2653202-22-1C9H11BrF2N2O
4-Bromo-3-(difluoromethyl)-1-(oxan-2-yl)-1H-pyrazole chemical structure, C9H11BrF2N2O, CAS 2416164-38-8
4-Bromo-3-(difluoromethyl)-1-(oxan-2-yl)-1H-pyrazole
CAS 2416164-38-8C9H11BrF2N2O
Ethyl 4-Nitro-1-(tetrahydro-2H-pyran-2-yl)pyrazole-3-carboxylate chemical structure, C11H15N3O5, CAS 2394877-03-1
Ethyl 4-Nitro-1-(tetrahydro-2H-pyran-2-yl)pyrazole-3-carboxylate
CAS 2394877-03-1C11H15N3O5
Ethyl 3-bromo-1-(oxan-2-yl)-1H-pyrazole-4-carboxylate chemical structure, C11H15BrN2O3, CAS 2768321-74-8
Ethyl 3-bromo-1-(oxan-2-yl)-1H-pyrazole-4-carboxylate
CAS 2768321-74-8C11H15BrN2O3