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Murcko scaffold

Ring system with 2 rings and 21 atoms

14 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
21
Chemicals
14
With full pages
8
Scaffold SMILES

O=C(CNS(=O)(=O)c1ccccc1)NCc1ccncc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNS(=O)(=O)c1ccccc1)NCc1ccncc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

2-[Benzenesulfonyl(methyl)amino]-N-(pyridin-4-ylmethyl)acetamide chemical structure, C15H17N3O3S, CAS 593262-18-1
2-[Benzenesulfonyl(methyl)amino]-N-(pyridin-4-ylmethyl)acetamide
CAS 593262-18-1C15H17N3O3S
2-[(2,5-Dichlorophenyl)sulfonyl-methylamino]-N-(pyridin-4-ylmethyl)acetamide chemical structure, C15H15Cl2N3O3S, CAS 678538-04-0
2-[(2,5-Dichlorophenyl)sulfonyl-methylamino]-N-(pyridin-4-ylmethyl)acetamide
CAS 678538-04-0C15H15Cl2N3O3S
2-[Methyl-(2,4,6-trimethylphenyl)sulfonylamino]-N-(pyridin-4-ylmethyl)acetamide chemical structure, C18H23N3O3S, CAS 675861-79-7
2-[Methyl-(2,4,6-trimethylphenyl)sulfonylamino]-N-(pyridin-4-ylmethyl)acetamide
CAS 675861-79-7C18H23N3O3S
2-[(4-Chlorophenyl)sulfonyl-ethylamino]-N-(pyridin-4-ylmethyl)acetamide chemical structure, C16H18ClN3O3S, CAS 713502-24-0
2-[(4-Chlorophenyl)sulfonyl-ethylamino]-N-(pyridin-4-ylmethyl)acetamide
CAS 713502-24-0C16H18ClN3O3S
2-[(4-Methoxy-3-methylphenyl)sulfonyl-methylamino]-N-(pyridin-4-ylmethyl)acetamide chemical structure, C17H21N3O4S, CAS 714214-13-8
2-[(4-Methoxy-3-methylphenyl)sulfonyl-methylamino]-N-(pyridin-4-ylmethyl)acetamide
CAS 714214-13-8C17H21N3O4S
2-[(4-Chlorophenyl)sulfonyl-methylamino]-N-(pyridin-4-ylmethyl)acetamide chemical structure, C15H16ClN3O3S, CAS 510716-58-2
2-[(4-Chlorophenyl)sulfonyl-methylamino]-N-(pyridin-4-ylmethyl)acetamide
CAS 510716-58-2C15H16ClN3O3S
2-[(4-Bromophenyl)sulfonyl-methylamino]-N-(pyridin-4-ylmethyl)acetamide chemical structure, C15H16BrN3O3S, CAS 593245-19-3
2-[(4-Bromophenyl)sulfonyl-methylamino]-N-(pyridin-4-ylmethyl)acetamide
CAS 593245-19-3C15H16BrN3O3S
2-[(3-Chloro-4-methoxyphenyl)sulfonyl-methylamino]-N-(pyridin-4-ylmethyl)acetamide chemical structure, C16H18ClN3O4S, CAS 833429-23-5
2-[(3-Chloro-4-methoxyphenyl)sulfonyl-methylamino]-N-(pyridin-4-ylmethyl)acetamide
CAS 833429-23-5C16H18ClN3O4S
2-[Ethyl-(4-methylphenyl)sulfonylamino]-N-(pyridin-4-ylmethyl)acetamide chemical structure, C17H21N3O3S, CAS 833441-14-8
2-[Ethyl-(4-methylphenyl)sulfonylamino]-N-(pyridin-4-ylmethyl)acetamide
CAS 833441-14-8C17H21N3O3S
2-[Ethyl-(4-fluorophenyl)sulfonylamino]-N-(pyridin-4-ylmethyl)acetamide chemical structure, C16H18FN3O3S, CAS 838890-93-0
2-[Ethyl-(4-fluorophenyl)sulfonylamino]-N-(pyridin-4-ylmethyl)acetamide
CAS 838890-93-0C16H18FN3O3S
2-[(4-Methoxyphenyl)sulfonylamino]-N-(pyridin-4-ylmethyl)propanamide chemical structure, C16H19N3O4S, CAS 1008021-48-4
2-[(4-Methoxyphenyl)sulfonylamino]-N-(pyridin-4-ylmethyl)propanamide
CAS 1008021-48-4C16H19N3O4S
2-[Ethyl-(4-methoxyphenyl)sulfonylamino]-N-(pyridin-4-ylmethyl)acetamide chemical structure, C17H21N3O4S, CAS 838899-82-4
2-[Ethyl-(4-methoxyphenyl)sulfonylamino]-N-(pyridin-4-ylmethyl)acetamide
CAS 838899-82-4C17H21N3O4S
2-[Benzenesulfonyl(ethyl)amino]-N-(pyridin-4-ylmethyl)acetamide chemical structure, C16H19N3O3S, CAS 847241-13-8
2-[Benzenesulfonyl(ethyl)amino]-N-(pyridin-4-ylmethyl)acetamide
CAS 847241-13-8C16H19N3O3S
2-(3-Chloro-4-methoxy-benzenesulfonylamino)-N-pyridin-4-ylmethyl-propionamide chemical structure, C16H18ClN3O4S, CAS 1033546-47-2
2-(3-Chloro-4-methoxy-benzenesulfonylamino)-N-pyridin-4-ylmethyl-propionamide
CAS 1033546-47-2C16H18ClN3O4S