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Murcko scaffold

Ring system with 3 rings and 20 atoms

34 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
34
With full pages
11
Scaffold SMILES

O=C(COc1ccccc1)N1CCCc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)N1CCCc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 34 of 34 chemicals

1-(3,4-Dihydro-2H-quinolin-1-yl)-2-p-tolyloxy-ethanone chemical structure, C18H19NO2, CAS 349473-92-3
1-(3,4-Dihydro-2H-quinolin-1-yl)-2-p-tolyloxy-ethanone
CAS 349473-92-3C18H19NO2
1-[(3-Methylphenoxy)acetyl]-1,2,3,4-tetrahydroquinoline chemical structure, C18H19NO2, CAS 349474-29-9
1-[(3-Methylphenoxy)acetyl]-1,2,3,4-tetrahydroquinoline
CAS 349474-29-9C18H19NO2
2-(4-Chloro-3,5-dimethylphenoxy)-1-(3,4-dihydro-2H-quinolin-1-yl)ethanone chemical structure, C19H20ClNO2, CAS 424803-87-2
2-(4-Chloro-3,5-dimethylphenoxy)-1-(3,4-dihydro-2H-quinolin-1-yl)ethanone
CAS 424803-87-2C19H20ClNO2
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-(o-tolyloxy)ethanone chemical structure, C18H19NO2, CAS 304676-35-5
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-(o-tolyloxy)ethanone
CAS 304676-35-5C18H19NO2
1-[(4-Bromophenoxy)acetyl]-1,2,3,4-tetrahydroquinoline chemical structure, C17H16BrNO2, CAS 433707-46-1
1-[(4-Bromophenoxy)acetyl]-1,2,3,4-tetrahydroquinoline
CAS 433707-46-1C17H16BrNO2
1-[(2,5-Dimethylphenoxy)acetyl]-1,2,3,4-tetrahydroquinoline chemical structure, C19H21NO2, CAS 443645-92-9
1-[(2,5-Dimethylphenoxy)acetyl]-1,2,3,4-tetrahydroquinoline
CAS 443645-92-9C19H21NO2
2-(2,4-Dichlorophenoxy)-1-(3,4-dihydro-2H-quinolin-1-yl)ethanone chemical structure, C17H15Cl2NO2, CAS 314022-05-4
2-(2,4-Dichlorophenoxy)-1-(3,4-dihydro-2H-quinolin-1-yl)ethanone
CAS 314022-05-4C17H15Cl2NO2
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-(4-fluorophenoxy)ethanone chemical structure, C17H16FNO2, CAS 609794-78-7
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-(4-fluorophenoxy)ethanone
CAS 609794-78-7C17H16FNO2
1-[(2-Chlorophenoxy)acetyl]-1,2,3,4-tetrahydroquinoline chemical structure, C17H16ClNO2, CAS 429629-48-1
1-[(2-Chlorophenoxy)acetyl]-1,2,3,4-tetrahydroquinoline
CAS 429629-48-1C17H16ClNO2
1-(3,4-Dihydro-2H-quinolin-1-yl)-2-(3,4-dimethylphenoxy)ethanone chemical structure, C19H21NO2, CAS 432541-69-0
1-(3,4-Dihydro-2H-quinolin-1-yl)-2-(3,4-dimethylphenoxy)ethanone
CAS 432541-69-0C19H21NO2
2-(4-Chloro-3-methylphenoxy)-1-(3,4-dihydroquinolin-1(2H)-yl)ethanone chemical structure, C18H18ClNO2, CAS 429633-08-9
2-(4-Chloro-3-methylphenoxy)-1-(3,4-dihydroquinolin-1(2H)-yl)ethanone
CAS 429633-08-9C18H18ClNO2
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-(2,3,5-trimethylphenoxy)ethanone chemical structure, C20H23NO2, CAS 690980-28-0
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-(2,3,5-trimethylphenoxy)ethanone
CAS 690980-28-0C20H23NO2
1-[(Mesityloxy)acetyl]-1,2,3,4-tetrahydroquinoline chemical structure, C20H23NO2, CAS 617676-54-7
1-[(Mesityloxy)acetyl]-1,2,3,4-tetrahydroquinoline
CAS 617676-54-7C20H23NO2
1-[(4-Bromo-2-methylphenoxy)acetyl]-1,2,3,4-tetrahydroquinoline chemical structure, C18H18BrNO2, CAS 434309-33-8
1-[(4-Bromo-2-methylphenoxy)acetyl]-1,2,3,4-tetrahydroquinoline
CAS 434309-33-8C18H18BrNO2
2-(2-Bromo-4-propan-2-ylphenoxy)-1-(3,4-dihydro-2H-quinolin-1-yl)ethanone chemical structure, C20H22BrNO2, CAS 693268-55-2
2-(2-Bromo-4-propan-2-ylphenoxy)-1-(3,4-dihydro-2H-quinolin-1-yl)ethanone
CAS 693268-55-2C20H22BrNO2
2-(4-Bromo-2-chlorophenoxy)-1-(3,4-dihydroquinolin-1(2H)-yl)ethanone chemical structure, C17H15BrClNO2, CAS 430457-31-1
2-(4-Bromo-2-chlorophenoxy)-1-(3,4-dihydroquinolin-1(2H)-yl)ethanone
CAS 430457-31-1C17H15BrClNO2
2-(2-Bromo-4-chlorophenoxy)-1-(3,4-dihydro-2H-quinolin-1-yl)ethanone chemical structure, C17H15BrClNO2, CAS 658046-26-5
2-(2-Bromo-4-chlorophenoxy)-1-(3,4-dihydro-2H-quinolin-1-yl)ethanone
CAS 658046-26-5C17H15BrClNO2
Methyl 4-[2-(3,4-dihydro-2H-quinolin-1-yl)-2-oxoethoxy]benzoate chemical structure, C19H19NO4, CAS 742090-23-9
Methyl 4-[2-(3,4-dihydro-2H-quinolin-1-yl)-2-oxoethoxy]benzoate
CAS 742090-23-9C19H19NO4
4-[2-(3,4-Dihydro-2H-quinolin-1-yl)-2-oxoethoxy]benzaldehyde chemical structure, C18H17NO3, CAS 722470-59-9
4-[2-(3,4-Dihydro-2H-quinolin-1-yl)-2-oxoethoxy]benzaldehyde
CAS 722470-59-9C18H17NO3
2-(3-Acetylphenoxy)-1-(3,4-dihydro-2H-quinolin-1-yl)ethanone chemical structure, C19H19NO3, CAS 796057-82-4
2-(3-Acetylphenoxy)-1-(3,4-dihydro-2H-quinolin-1-yl)ethanone
CAS 796057-82-4C19H19NO3
2-(4-Chlorophenoxy)-1-(6-fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl)ethanone chemical structure, C18H17ClFNO2, CAS 309951-58-4
2-(4-Chlorophenoxy)-1-(6-fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl)ethanone
CAS 309951-58-4C18H17ClFNO2
1-[2-(2,4-Dichlorophenoxy)propanoyl]-1,2,3,4-tetrahydroquinoline chemical structure, C18H17Cl2NO2, CAS 353768-42-0
1-[2-(2,4-Dichlorophenoxy)propanoyl]-1,2,3,4-tetrahydroquinoline
CAS 353768-42-0C18H17Cl2NO2
1-(3,4-Dihydro-2H-quinolin-1-yl)-2-phenoxypropan-1-one chemical structure, C18H19NO2, CAS 349579-43-7
1-(3,4-Dihydro-2H-quinolin-1-yl)-2-phenoxypropan-1-one
CAS 349579-43-7C18H19NO2
2-(2,4-Dichlorophenoxy)-1-(6-fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl)ethanone chemical structure, C18H16Cl2FNO2, CAS 543702-78-9
2-(2,4-Dichlorophenoxy)-1-(6-fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl)ethanone
CAS 543702-78-9C18H16Cl2FNO2