CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 20 atoms

19 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
19
With full pages
9
Scaffold SMILES

O=C(NCc1ccccc1)c1ccnc2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCc1ccccc1)c1ccnc2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

N-Benzyl-2-methylquinoline-4-carboxamide chemical structure, C18H16N2O, CAS 313277-47-3
N-Benzyl-2-methylquinoline-4-carboxamide
CAS 313277-47-3C18H16N2O
N-[(3-Chlorophenyl)methyl]-2-methylquinoline-4-carboxamide chemical structure, C18H15ClN2O, CAS 763100-96-5
N-[(3-Chlorophenyl)methyl]-2-methylquinoline-4-carboxamide
CAS 763100-96-5C18H15ClN2O
N-(2-Methoxybenzyl)-2-methylquinoline-4-carboxamide chemical structure, C19H18N2O2, CAS 877834-32-7
N-(2-Methoxybenzyl)-2-methylquinoline-4-carboxamide
CAS 877834-32-7C19H18N2O2
6-Fluoro-2-methyl-N-(1-phenylethyl)quinoline-4-carboxamide chemical structure, C19H17FN2O, CAS 623547-11-5
6-Fluoro-2-methyl-N-(1-phenylethyl)quinoline-4-carboxamide
CAS 623547-11-5C19H17FN2O
N-[(2-Chlorophenyl)methyl]-2-methylquinoline-4-carboxamide chemical structure, C18H15ClN2O, CAS 690220-95-2
N-[(2-Chlorophenyl)methyl]-2-methylquinoline-4-carboxamide
CAS 690220-95-2C18H15ClN2O
N-[(3-Methoxyphenyl)methyl]-2-methylquinoline-4-carboxamide chemical structure, C19H18N2O2, CAS 690221-15-9
N-[(3-Methoxyphenyl)methyl]-2-methylquinoline-4-carboxamide
CAS 690221-15-9C19H18N2O2
N-[(4-Fluorophenyl)methyl]-2-methylquinoline-4-carboxamide chemical structure, C18H15FN2O, CAS 805272-65-5
N-[(4-Fluorophenyl)methyl]-2-methylquinoline-4-carboxamide
CAS 805272-65-5C18H15FN2O
N-[(2-Fluorophenyl)methyl]-2-methylquinoline-4-carboxamide chemical structure, C18H15FN2O, CAS 690221-26-2
N-[(2-Fluorophenyl)methyl]-2-methylquinoline-4-carboxamide
CAS 690221-26-2C18H15FN2O
2-Ethyl-N-[(4-methoxyphenyl)methyl]-3-methylquinoline-4-carboxamide chemical structure, C21H22N2O2, CAS 791086-05-0
2-Ethyl-N-[(4-methoxyphenyl)methyl]-3-methylquinoline-4-carboxamide
CAS 791086-05-0C21H22N2O2
2-Chloro-N-[(2-methoxyphenyl)methyl]quinoline-4-carboxamide chemical structure, C18H15ClN2O2, CAS 1375252-41-7
2-Chloro-N-[(2-methoxyphenyl)methyl]quinoline-4-carboxamide
CAS 1375252-41-7C18H15ClN2O2
N-[(2-Chloro-6-fluorophenyl)methyl]-N,2-dimethylquinoline-4-carboxamide chemical structure, C19H16ClFN2O, CAS 878110-50-0
N-[(2-Chloro-6-fluorophenyl)methyl]-N,2-dimethylquinoline-4-carboxamide
CAS 878110-50-0C19H16ClFN2O
7-Methoxy-2-methyl-N-(phenylmethyl)-4-quinolinecarboxamide chemical structure, C19H18N2O2, CAS 763907-32-0
7-Methoxy-2-methyl-N-(phenylmethyl)-4-quinolinecarboxamide
CAS 763907-32-0C19H18N2O2
2-Chloro-N-[1-(2-fluorophenyl)ethyl]quinoline-4-carboxamide chemical structure, C18H14ClFN2O, CAS 877981-05-0
2-Chloro-N-[1-(2-fluorophenyl)ethyl]quinoline-4-carboxamide
CAS 877981-05-0C18H14ClFN2O
2-Chloro-N-[(2,3-dimethoxyphenyl)methyl]-N-methylquinoline-4-carboxamide chemical structure, C20H19ClN2O3, CAS 924452-37-9
2-Chloro-N-[(2,3-dimethoxyphenyl)methyl]-N-methylquinoline-4-carboxamide
CAS 924452-37-9C20H19ClN2O3
2-Chloro-N-[(3-fluoro-4-methoxyphenyl)methyl]-N-methylquinoline-4-carboxamide chemical structure, C19H16ClFN2O2, CAS 924439-62-3
2-Chloro-N-[(3-fluoro-4-methoxyphenyl)methyl]-N-methylquinoline-4-carboxamide
CAS 924439-62-3C19H16ClFN2O2
2-Chloro-N-[(3,4,5-trimethoxyphenyl)methyl]quinoline-4-carboxamide chemical structure, C20H19ClN2O4, CAS 1118834-20-0
2-Chloro-N-[(3,4,5-trimethoxyphenyl)methyl]quinoline-4-carboxamide
CAS 1118834-20-0C20H19ClN2O4
6-Methoxy-N-[(4-sulfamoylphenyl)methyl]quinoline-4-carboxamide chemical structure, C18H17N3O4S, CAS 2415566-24-2
6-Methoxy-N-[(4-sulfamoylphenyl)methyl]quinoline-4-carboxamide
CAS 2415566-24-2C18H17N3O4S
N-[(2-Fluorophenyl)methyl]-6-methoxyquinoline-4-carboxamide chemical structure, C18H15FN2O2, CAS 2415631-74-0
N-[(2-Fluorophenyl)methyl]-6-methoxyquinoline-4-carboxamide
CAS 2415631-74-0C18H15FN2O2
N-[(2,4-Dimethoxyphenyl)methyl]-6-methoxyquinoline-4-carboxamide chemical structure, C20H20N2O4, CAS 2415542-74-2
N-[(2,4-Dimethoxyphenyl)methyl]-6-methoxyquinoline-4-carboxamide
CAS 2415542-74-2C20H20N2O4