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Murcko scaffold

Ring system with 3 rings and 20 atoms

21 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
21
With full pages
17
Scaffold SMILES

O=C(COc1ccccc1)N1CCOc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)N1CCOc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

Methyl 4-(phenoxyacetyl)-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate chemical structure, C18H17NO5, CAS 879948-63-7
Methyl 4-(phenoxyacetyl)-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate
CAS 879948-63-7C18H17NO5
4-[2-(4-Ethylphenoxy)acetyl]-2,3-dihydro-1,4-benzoxazine-2-carboxamide chemical structure, C19H20N2O4, CAS 878571-54-1
4-[2-(4-Ethylphenoxy)acetyl]-2,3-dihydro-1,4-benzoxazine-2-carboxamide
CAS 878571-54-1C19H20N2O4
Methyl 4-[(4-chlorophenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate chemical structure, C18H16ClNO5, CAS 879947-76-9
Methyl 4-[(4-chlorophenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate
CAS 879947-76-9C18H16ClNO5
Methyl 4-[2-(4-fluorophenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate chemical structure, C18H16FNO5, CAS 879947-84-9
Methyl 4-[2-(4-fluorophenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate
CAS 879947-84-9C18H16FNO5
Methyl 4-[(3,4-dimethylphenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate chemical structure, C20H21NO5, CAS 879948-33-1
Methyl 4-[(3,4-dimethylphenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate
CAS 879948-33-1C20H21NO5
Methyl 4-[(4-chloro-3,5-dimethylphenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate chemical structure, C20H20ClNO5, CAS 881445-25-6
Methyl 4-[(4-chloro-3,5-dimethylphenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate
CAS 881445-25-6C20H20ClNO5
Methyl 4-[2-(2-isopropyl-5-methylphenoxy)propanoyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate chemical structure, C23H27NO5, CAS 879948-49-9
Methyl 4-[2-(2-isopropyl-5-methylphenoxy)propanoyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate
CAS 879948-49-9C23H27NO5
Methyl 4-[(3,5-dimethylphenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate chemical structure, C20H21NO5, CAS 879948-56-8
Methyl 4-[(3,5-dimethylphenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate
CAS 879948-56-8C20H21NO5
Methyl 4-[(2-methylphenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate chemical structure, C19H19NO5, CAS 879948-70-6
Methyl 4-[(2-methylphenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate
CAS 879948-70-6C19H19NO5
Methyl 4-[(4-methylphenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate chemical structure, C19H19NO5, CAS 879948-76-2
Methyl 4-[(4-methylphenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate
CAS 879948-76-2C19H19NO5
Methyl 4-[(2,3-dimethylphenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate chemical structure, C20H21NO5, CAS 879948-82-0
Methyl 4-[(2,3-dimethylphenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate
CAS 879948-82-0C20H21NO5
Methyl 4-[2-(2-chlorophenoxy)propanoyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate chemical structure, C19H18ClNO5, CAS 879951-96-9
Methyl 4-[2-(2-chlorophenoxy)propanoyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate
CAS 879951-96-9C19H18ClNO5
Methyl 4-[2-(4-isopropylphenoxy)propanoyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate chemical structure, C22H25NO5, CAS 879952-04-2
Methyl 4-[2-(4-isopropylphenoxy)propanoyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate
CAS 879952-04-2C22H25NO5
Methyl 4-[(2,4-dichlorophenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate chemical structure, C18H15Cl2NO5, CAS 879953-54-5
Methyl 4-[(2,4-dichlorophenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate
CAS 879953-54-5C18H15Cl2NO5
Methyl 4-[(2-methoxyphenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate chemical structure, C19H19NO6, CAS 879953-60-3
Methyl 4-[(2-methoxyphenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate
CAS 879953-60-3C19H19NO6
Methyl 4-[(4-chloro-2-methylphenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate chemical structure, C19H18ClNO5, CAS 879954-02-6
Methyl 4-[(4-chloro-2-methylphenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate
CAS 879954-02-6C19H18ClNO5
Methyl 4-[2-(4-fluorophenoxy)propanoyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate chemical structure, C19H18FNO5, CAS 879954-33-3
Methyl 4-[2-(4-fluorophenoxy)propanoyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate
CAS 879954-33-3C19H18FNO5
Methyl 4-[(4-ethylphenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate chemical structure, C20H21NO5, CAS 879954-49-1
Methyl 4-[(4-ethylphenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate
CAS 879954-49-1C20H21NO5
Methyl 4-[2-(3,4-dimethylphenoxy)propanoyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate chemical structure, C21H23NO5, CAS 881216-82-6
Methyl 4-[2-(3,4-dimethylphenoxy)propanoyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate
CAS 881216-82-6C21H23NO5
Methyl 4-[(4-chloro-3-methylphenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate chemical structure, C19H18ClNO5, CAS 879954-57-1
Methyl 4-[(4-chloro-3-methylphenoxy)acetyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate
CAS 879954-57-1C19H18ClNO5
Methyl 4-[2-(2-fluorophenoxy)butanoyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate chemical structure, C20H20FNO5, CAS 879954-73-1
Methyl 4-[2-(2-fluorophenoxy)butanoyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate
CAS 879954-73-1C20H20FNO5