Murcko scaffold
Ring system with 2 rings and 15 atoms
64 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 15
- Chemicals
- 64
- With full pages
- 7
Scaffold SMILES
O=S(=O)(Cc1ccco1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 64 chemicals
![2-[(Benzenesulfonyl)methyl]-5-nitrofuran chemical structure, C11H9NO5S, CAS 40941-17-1](/s/BULZZUJNSQZAJI-UHFFFAOYSA-N.svg)
2-[(Benzenesulfonyl)methyl]-5-nitrofuran
CAS 40941-17-1C11H9NO5S
![Methyl 5-[(phenylsulfonyl)methyl]-2-furoate chemical structure, C13H12O5S, CAS 91903-72-9](/s/ZBQTVMXADXLQBU-UHFFFAOYSA-N.svg)
Methyl 5-[(phenylsulfonyl)methyl]-2-furoate
CAS 91903-72-9C13H12O5S
Methyl 5-(((4-bromophenyl)sulfonyl)methyl)furan-2-carboxylate
CAS 886498-54-0C13H11BrO5S
Methyl 5-(((4-chlorophenyl)sulfonyl)methyl)furan-2-carboxylate
CAS 886498-59-5C13H11ClO5S
5-((Benzenesulfonyl)methyl)furan-2-carboxylic acid
CAS 92959-89-2C12H10O5S
5-((Benzenesulfonyl)methyl)furan-2-carbohydrazide
CAS 852840-58-5C12H12N2O4S
![5-{[(4-Methylphenyl)sulfonyl]methyl}furan-2-carboxylic acid chemical structure, C13H12O5S, CAS 897769-35-6](/s/VNPAVLDSIONFMU-UHFFFAOYSA-N.svg)
5-{[(4-Methylphenyl)sulfonyl]methyl}furan-2-carboxylic acid
CAS 897769-35-6C13H12O5S
![2-[(4-Chlorobenzene-1-sulfonyl)methyl]-5-nitrofuran chemical structure, C11H8ClNO5S, CAS 61266-27-1](/s/JZCRSXFJFIZPNI-UHFFFAOYSA-N.svg)
2-[(4-Chlorobenzene-1-sulfonyl)methyl]-5-nitrofuran
CAS 61266-27-1C11H8ClNO5S
![2-(2-Furyl)-2-[(4-methoxyphenyl)sulphonyl]ethylamine chemical structure, C13H15NO4S, CAS 903094-86-0](/s/JPOTVNMYTULOKV-UHFFFAOYSA-N.svg)
2-(2-Furyl)-2-[(4-methoxyphenyl)sulphonyl]ethylamine
CAS 903094-86-0C13H15NO4S
![2-(2-Furyl)-2-[(4-methylphenyl)sulphonyl]ethylamine chemical structure, C13H15NO3S, CAS 887345-60-0](/s/AWZAXZGLXPRXEG-UHFFFAOYSA-N.svg)
2-(2-Furyl)-2-[(4-methylphenyl)sulphonyl]ethylamine
CAS 887345-60-0C13H15NO3S
2-(Furan-2-yl)-2-(phenylsulfonyl)ethanamine
CAS 1177327-36-4C12H13NO3S
![2-[(4-Fluorophenyl)sulfonyl]-2-(furan-2-yl)ethanamine chemical structure, C12H12FNO3S, CAS 1094394-43-0](/s/URJQPAUTQSLYPA-UHFFFAOYSA-N.svg)
2-[(4-Fluorophenyl)sulfonyl]-2-(furan-2-yl)ethanamine
CAS 1094394-43-0C12H12FNO3S
![2-[(4-Chlorophenyl)sulfonyl]-2-(furan-2-yl)ethanamine chemical structure, C12H12ClNO3S, CAS 1094394-73-6](/s/QANQGFDLCIPOEV-UHFFFAOYSA-N.svg)
2-[(4-Chlorophenyl)sulfonyl]-2-(furan-2-yl)ethanamine
CAS 1094394-73-6C12H12ClNO3S
Ethyl 2-((2-(furan-2-yl)-2-(phenylsulfonyl)ethyl)amino)-2-oxoacetate
CAS 896316-95-3C16H17NO6S
N1-allyl-N2-(2-((4-chlorophenyl)sulfonyl)-2-(furan-2-yl)ethyl)oxalamide
CAS 896328-94-2C17H17ClN2O5S
N1-butyl-N2-(2-((4-chlorophenyl)sulfonyl)-2-(furan-2-yl)ethyl)oxalamide
CAS 896329-44-5C18H21ClN2O5S
N1-(2-((4-chlorophenyl)sulfonyl)-2-(furan-2-yl)ethyl)-N2-(2-methoxyethyl)oxalamide
CAS 896329-51-4C17H19ClN2O6S
Ethyl 2-((2-((4-chlorophenyl)sulfonyl)-2-(furan-2-yl)ethyl)amino)-2-oxoacetate
CAS 896332-12-0C16H16ClNO6S
N-(2-((4-Fluorophenyl)sulfonyl)-2-(furan-2-yl)ethyl)ethanesulfonamide
CAS 896327-46-1C14H16FNO5S2
![Methyl 5-{[(4-methylphenyl)sulfonyl]methyl}-2-furoate chemical structure, C14H14O5S, CAS 897775-93-8](/s/ZIQVEAJAOQEMSS-UHFFFAOYSA-N.svg)
Methyl 5-{[(4-methylphenyl)sulfonyl]methyl}-2-furoate
CAS 897775-93-8C14H14O5S
![5-{[(4-Methoxyphenyl)sulfonyl]methyl}-2-furoic acid chemical structure, C13H12O6S, CAS 897769-50-5](/s/VLQOGKJKTDLBDD-UHFFFAOYSA-N.svg)
5-{[(4-Methoxyphenyl)sulfonyl]methyl}-2-furoic acid
CAS 897769-50-5C13H12O6S
![5-{[(4-Bromophenyl)sulfonyl]methyl}-2-furoic acid chemical structure, C12H9BrO5S, CAS 897776-09-9](/s/FPDXNOQMUBINIO-UHFFFAOYSA-N.svg)
5-{[(4-Bromophenyl)sulfonyl]methyl}-2-furoic acid
CAS 897776-09-9C12H9BrO5S
![5-[(2,6-Dichlorobenzenesulfonyl)methyl]furan-2-carboxylic acid chemical structure, C12H8Cl2O5S, CAS 897765-60-5](/s/NGHVBUYUARLTIX-UHFFFAOYSA-N.svg)
5-[(2,6-Dichlorobenzenesulfonyl)methyl]furan-2-carboxylic acid
CAS 897765-60-5C12H8Cl2O5S
2-(Furan-2-yl)-2-(phenylsulfonyl)ethanamine hydrochloride
C12H14ClNO3S
- N'-[2-(Benzenesulfonyl)-2-(furan-2-yl)ethyl]-N-propylethanediamide896313-65-8C17H20N2O5S
- N'-[2-(Benzenesulfonyl)-2-(furan-2-yl)ethyl]-N-butylethanediamide896314-21-9C18H22N2O5S
- N'-[2-(Benzenesulfonyl)-2-(furan-2-yl)ethyl]-N-(2-methoxyethyl)ethanediamide896314-28-6C17H20N2O6S
- N'-[2-(Benzenesulfonyl)-2-(furan-2-yl)ethyl]-N-(2-hydroxyethyl)ethanediamide896314-72-0C16H18N2O6S
- N'-[2-(Benzenesulfonyl)-2-(furan-2-yl)ethyl]-N-ethylethanediamide896318-67-5C16H18N2O5S
- N'-[2-(Benzenesulfonyl)-2-(furan-2-yl)ethyl]-N-(propan-2-yl)ethanediamide896318-75-5C17H20N2O5S
- N'-[2-(Benzenesulfonyl)-2-(furan-2-yl)ethyl]-N-(2-methylpropyl)ethanediamide896319-06-5C18H22N2O5S
- N'-[2-(Furan-2-yl)-2-(4-methylbenzenesulfonyl)ethyl]-N-propylethanediamide896321-41-8C18H22N2O5S
- N'-[2-(Furan-2-yl)-2-(4-methylbenzenesulfonyl)ethyl]-N-(prop-2-en-1-yl)ethanediamide896321-47-4C18H20N2O5S
- N'-[2-(Furan-2-yl)-2-(4-methylbenzenesulfonyl)ethyl]-N-(3-methylbutyl)ethanediamide896321-55-4C20H26N2O5S
- N-[2-(Dimethylamino)ethyl]-N'-[2-(furan-2-yl)-2-(4-methylbenzenesulfonyl)ethyl]ethanediamide887216-32-2C19H25N3O5S
- N-Butyl-N'-[2-(furan-2-yl)-2-(4-methylbenzenesulfonyl)ethyl]ethanediamide896321-99-6C19H24N2O5S
- N'-[2-(Furan-2-yl)-2-(4-methylbenzenesulfonyl)ethyl]-N-(2-methoxyethyl)ethanediamide896322-05-7C18H22N2O6S
- N'-[2-(Furan-2-yl)-2-(4-methylbenzenesulfonyl)ethyl]-N-(2-hydroxyethyl)ethanediamide896322-47-7C17H20N2O6S
- N'-[2-(Furan-2-yl)-2-(4-methylbenzenesulfonyl)ethyl]-N-methylethanediamide896326-16-2C16H18N2O5S
- N'-[2-(Furan-2-yl)-2-(4-methylbenzenesulfonyl)ethyl]-N-(2-methylpropyl)ethanediamide896326-57-1C19H24N2O5S
- N'-[2-(4-Chlorobenzenesulfonyl)-2-(furan-2-yl)ethyl]-N-(3-methylbutyl)ethanediamide896329-01-4C19H23ClN2O5S
- N'-[2-(4-Chlorobenzenesulfonyl)-2-(furan-2-yl)ethyl]-N-(2-hydroxyethyl)ethanediamide896329-95-6C16H17ClN2O6S
- N'-[2-(4-Chlorobenzenesulfonyl)-2-(furan-2-yl)ethyl]-N-methylethanediamide896333-60-1C15H15ClN2O5S
- N'-[2-(4-Chlorobenzenesulfonyl)-2-(furan-2-yl)ethyl]-N-ethylethanediamide896333-67-8C16H17ClN2O5S
- N1-(2-((4-chlorophenyl)sulfonyl)-2-(furan-2-yl)ethyl)-N2-isobutyloxalamide896334-01-3C18H21ClN2O5S
- N'-[2-(4-Fluorobenzenesulfonyl)-2-(furan-2-yl)ethyl]-N-(3-methylbutyl)ethanediamide896336-47-3C19H23FN2O5S
- N-[2-(Dimethylamino)ethyl]-N'-[2-(4-fluorobenzenesulfonyl)-2-(furan-2-yl)ethyl]ethanediamide896336-55-3C18H22FN3O5S
- N'-[2-(4-Fluorobenzenesulfonyl)-2-(furan-2-yl)ethyl]-N-(2-methoxyethyl)ethanediamide896308-75-1C17H19FN2O6S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)c1ccco1208 chemicals
O=C(Nc1ccccc1)c1cccs1150 chemicals
O=C(Nc1nccs1)c1ccccc1121 chemicals![Scaffold O=C(N=c1[nH]ncs1)c1ccccc1](/scaffold/RWOUBULBQYRRNL-UHFFFAOYSA-N/structure.svg)
O=C(N=c1[nH]ncs1)c1ccccc187 chemicals
c1ccc(OCc2ccco2)cc175 chemicals
O=S(=O)(Nc1nccs1)c1ccccc161 chemicals![Scaffold c1ccc(CSc2ncn[nH]2)cc1](/scaffold/IQQYSQRJFHUASD-UHFFFAOYSA-N/structure.svg)
c1ccc(CSc2ncn[nH]2)cc160 chemicals![Scaffold O=C(Nc1ccccc1)c1cc[nH]n1](/scaffold/WMZYZYFPPQOFKY-UHFFFAOYSA-N/structure.svg)
O=C(Nc1ccccc1)c1cc[nH]n160 chemicals
O=C(Nc1cccs1)c1ccccc152 chemicals
O=C(Nc1ccccc1)C1CCCO150 chemicals
O=C(Nc1ccccc1)c1ccoc148 chemicals
c1ccc(CSc2nncs2)cc144 chemicals