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Murcko scaffold

4-(2-Thiazolyl)pyridine scaffold

139 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
139
With full pages
11
Scaffold SMILES

c1cc(-c2nccs2)ccn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(2-Thiazolyl)pyridine page
Murcko scaffold c1cc(-c2nccs2)ccn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 139 chemicals

4-(4-Methyl-2-thiazolyl)pyridine chemical structure, C9H8N2S, CAS 23921-91-7
4-(4-Methyl-2-thiazolyl)pyridine
CAS 23921-91-7C9H8N2S
Ethyl 2-(pyridin-4-yl)thiazole-4-carboxylate chemical structure, C11H10N2O2S, CAS 21278-85-3
Ethyl 2-(pyridin-4-yl)thiazole-4-carboxylate
CAS 21278-85-3C11H10N2O2S
Ethyl 4-methyl-2-(pyridin-4-yl)-1,3-thiazole-5-carboxylate chemical structure, C12H12N2O2S, CAS 89401-54-7
Ethyl 4-methyl-2-(pyridin-4-yl)-1,3-thiazole-5-carboxylate
CAS 89401-54-7C12H12N2O2S
2-(Pyridin-4-yl)-1,3-thiazole-4-carboxylic acid chemical structure, C9H6N2O2S, CAS 21278-86-4
2-(Pyridin-4-yl)-1,3-thiazole-4-carboxylic acid
CAS 21278-86-4C9H6N2O2S
4-Thiazolecarboxamide, N-methyl-2-(4-pyridinyl)- chemical structure, C10H9N3OS, CAS 89401-58-1
4-Thiazolecarboxamide, N-methyl-2-(4-pyridinyl)-
CAS 89401-58-1C10H9N3OS
2-(4-Pyridyl)-4-methylthiazole-5-carboxylic acid chemical structure, C10H8N2O2S, CAS 144060-98-0
2-(4-Pyridyl)-4-methylthiazole-5-carboxylic acid
CAS 144060-98-0C10H8N2O2S
1-(4-Methyl-2-(pyridin-4-yl)thiazol-5-yl)ethanone chemical structure, C11H10N2OS, CAS 478077-75-7
1-(4-Methyl-2-(pyridin-4-yl)thiazol-5-yl)ethanone
CAS 478077-75-7C11H10N2OS
(E)-3-(Dimethylamino)-1-(4-methyl-2-pyridin-4-yl-1,3-thiazol-5-yl)prop-2-en-1-one chemical structure, C14H15N3OS, CAS 478257-67-9
(E)-3-(Dimethylamino)-1-(4-methyl-2-pyridin-4-yl-1,3-thiazol-5-yl)prop-2-en-1-one
CAS 478257-67-9C14H15N3OS
5-Methyl-2-(4-pyridinyl)-1,3-thiazol-4-ol chemical structure, C9H8N2OS, CAS 70547-50-1
5-Methyl-2-(4-pyridinyl)-1,3-thiazol-4-ol
CAS 70547-50-1C9H8N2OS
2-Pyridin-4-yl-1,3-thiazole-4-carbohydrazide chemical structure, C9H8N4OS, CAS 21278-87-5
2-Pyridin-4-yl-1,3-thiazole-4-carbohydrazide
CAS 21278-87-5C9H8N4OS
4-Thiazolecarboxamide, 2-(4-pyridinyl)- chemical structure, C9H7N3OS, CAS 89401-57-0
4-Thiazolecarboxamide, 2-(4-pyridinyl)-
CAS 89401-57-0C9H7N3OS
N-[3-(Dimethylamino)propyl]-2-(4-pyridinyl)-1,3-thiazole-4-carboxamide chemical structure, C14H18N4OS, CAS 321429-91-8
N-[3-(Dimethylamino)propyl]-2-(4-pyridinyl)-1,3-thiazole-4-carboxamide
CAS 321429-91-8C14H18N4OS
(2-Pyridin-4-yl-thiazol-4-yl)-acetic acid chemical structure, C10H8N2O2S, CAS 31112-92-2
(2-Pyridin-4-yl-thiazol-4-yl)-acetic acid
CAS 31112-92-2C10H8N2O2S
Ethyl 2-(2-(pyridin-4-yl)thiazol-4-yl)acetate chemical structure, C12H12N2O2S, CAS 80653-68-5
Ethyl 2-(2-(pyridin-4-yl)thiazol-4-yl)acetate
CAS 80653-68-5C12H12N2O2S
5-Methyl-2-(4-pyridyl)-1,3-thiazole-4-carboxylic acid chemical structure, C10H8N2O2S, CAS 889940-62-9
5-Methyl-2-(4-pyridyl)-1,3-thiazole-4-carboxylic acid
CAS 889940-62-9C10H8N2O2S
2-[2-(4-Pyridyl)thiazol-4-yl]acetamide chemical structure, C10H9N3OS, CAS 31112-96-6
2-[2-(4-Pyridyl)thiazol-4-yl]acetamide
CAS 31112-96-6C10H9N3OS
2-Pyridin-4-YL-thiazol-4-ylamine chemical structure, C8H7N3S, CAS 89401-67-2
2-Pyridin-4-YL-thiazol-4-ylamine
CAS 89401-67-2C8H7N3S
2-(4-Pyridinyl)-4-thiazolol chemical structure, C8H6N2OS, CAS 285995-73-5
2-(4-Pyridinyl)-4-thiazolol
CAS 285995-73-5C8H6N2OS
Ethyl 2-(pyridin-4-yl)-1,3-thiazole-4-carboxylate hydrobromide chemical structure, C11H11BrN2O2S, CAS 89401-56-9
Ethyl 2-(pyridin-4-yl)-1,3-thiazole-4-carboxylate hydrobromide
CAS 89401-56-9C11H11BrN2O2S
2-(Pyridin-4-yl)-1,3-thiazole-4-carbonitrile chemical structure, C9H5N3S, CAS 89401-60-5
2-(Pyridin-4-yl)-1,3-thiazole-4-carbonitrile
CAS 89401-60-5C9H5N3S
2-(Pyridin-4-yl)-1,3-thiazole-4-carboximidamide chemical structure, C9H8N4S, CAS 89401-73-0
2-(Pyridin-4-yl)-1,3-thiazole-4-carboximidamide
CAS 89401-73-0C9H8N4S
2-(Pyridin-4-yl)-1,3-thiazole-5-carboxamide chemical structure, C9H7N3OS, CAS 89401-53-6
2-(Pyridin-4-yl)-1,3-thiazole-5-carboxamide
CAS 89401-53-6C9H7N3OS
N-(2-Hydroxyethyl)-2-(pyridin-4-yl)-1,3-thiazole-4-carboxamide chemical structure, C11H11N3O2S, CAS 89401-59-2
N-(2-Hydroxyethyl)-2-(pyridin-4-yl)-1,3-thiazole-4-carboxamide
CAS 89401-59-2C11H11N3O2S
2-(Pyridin-4-yl)-1,3-thiazole-4-carbothioamide chemical structure, C9H7N3S2, CAS 89401-62-7
2-(Pyridin-4-yl)-1,3-thiazole-4-carbothioamide
CAS 89401-62-7C9H7N3S2