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Murcko scaffold

Ring system with 3 rings and 23 atoms

5 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
5
With full pages
3
Scaffold SMILES

O=C(Nc1ccc(C(=O)c2ccncc2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc(C(=O)c2ccncc2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

N-(4-Isonicotinoylphenyl)-4-methylbenzamide chemical structure, C20H16N2O2, CAS 356084-42-9
N-(4-Isonicotinoylphenyl)-4-methylbenzamide
CAS 356084-42-9C20H16N2O2
N-(4-Isonicotinoylphenyl)-3-methylbenzamide chemical structure, C20H16N2O2, CAS 650594-33-5
N-(4-Isonicotinoylphenyl)-3-methylbenzamide
CAS 650594-33-5C20H16N2O2
3,5-Dimethoxy-N-[4-(pyridine-4-carbonyl)phenyl]benzamide chemical structure, C21H18N2O4, CAS 676613-25-5
3,5-Dimethoxy-N-[4-(pyridine-4-carbonyl)phenyl]benzamide
CAS 676613-25-5C21H18N2O4
3,4,5-Trimethoxy-N-[4-(pyridine-4-carbonyl)phenyl]benzamide chemical structure, C22H20N2O5, CAS 356098-58-3
3,4,5-Trimethoxy-N-[4-(pyridine-4-carbonyl)phenyl]benzamide
CAS 356098-58-3C22H20N2O5
2,6-Dimethoxy-N-[4-(pyridine-4-carbonyl)phenyl]benzamide chemical structure, C21H18N2O4, CAS 728027-29-0
2,6-Dimethoxy-N-[4-(pyridine-4-carbonyl)phenyl]benzamide
CAS 728027-29-0C21H18N2O4