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Murcko scaffold

Ring system with 3 rings and 24 atoms

21 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
21
With full pages
12
Scaffold SMILES

O=C(Nc1ccc(S(=O)(=O)N2CCNCC2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc(S(=O)(=O)N2CCNCC2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

N-{4-[(4-Methyl-1-piperazinyl)sulfonyl]phenyl}benzamide chemical structure, C18H21N3O3S, CAS 717867-56-6
N-{4-[(4-Methyl-1-piperazinyl)sulfonyl]phenyl}benzamide
CAS 717867-56-6C18H21N3O3S
4-Fluoro-N-{4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl}benzamide chemical structure, C18H20FN3O3S, CAS 712318-72-4
4-Fluoro-N-{4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl}benzamide
CAS 712318-72-4C18H20FN3O3S
2-Methoxy-N-{4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl}benzamide chemical structure, C19H23N3O4S, CAS 791791-14-5
2-Methoxy-N-{4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl}benzamide
CAS 791791-14-5C19H23N3O4S
2,4-Dichloro-N-{4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl}benzamide chemical structure, C18H19Cl2N3O3S, CAS 712318-73-5
2,4-Dichloro-N-{4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl}benzamide
CAS 712318-73-5C18H19Cl2N3O3S
4-Methoxy-N-{4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl}benzamide chemical structure, C19H23N3O4S, CAS 712318-76-8
4-Methoxy-N-{4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl}benzamide
CAS 712318-76-8C19H23N3O4S
4-Methyl-N-{4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl}benzamide chemical structure, C19H23N3O3S, CAS 791791-43-0
4-Methyl-N-{4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl}benzamide
CAS 791791-43-0C19H23N3O3S
2-Methyl-N-{4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl}benzamide chemical structure, C19H23N3O3S, CAS 712318-71-3
2-Methyl-N-{4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl}benzamide
CAS 712318-71-3C19H23N3O3S
2-Ethoxy-N-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]benzamide chemical structure, C20H25N3O4S, CAS 876035-66-4
2-Ethoxy-N-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]benzamide
CAS 876035-66-4C20H25N3O4S
N-[4-(4-Methylpiperazin-1-yl)sulfonylphenyl]-4-propoxybenzamide chemical structure, C21H27N3O4S, CAS 876180-02-8
N-[4-(4-Methylpiperazin-1-yl)sulfonylphenyl]-4-propoxybenzamide
CAS 876180-02-8C21H27N3O4S
4-Ethoxy-N-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]benzamide chemical structure, C20H25N3O4S, CAS 875052-99-6
4-Ethoxy-N-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]benzamide
CAS 875052-99-6C20H25N3O4S
2-Fluoro-N-{4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl}benzamide chemical structure, C18H20FN3O3S, CAS 879026-39-8
2-Fluoro-N-{4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl}benzamide
CAS 879026-39-8C18H20FN3O3S
4-Isopropoxy-N-{4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl}benzamide chemical structure, C21H27N3O4S, CAS 879917-29-0
4-Isopropoxy-N-{4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl}benzamide
CAS 879917-29-0C21H27N3O4S
3-(3-Methylbutoxy)-N-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]benzamide chemical structure, C23H31N3O4S, CAS 882582-26-5
3-(3-Methylbutoxy)-N-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]benzamide
CAS 882582-26-5C23H31N3O4S
3-Fluoro-N-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]benzamide chemical structure, C18H20FN3O3S, CAS 879917-57-4
3-Fluoro-N-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]benzamide
CAS 879917-57-4C18H20FN3O3S
2-Chloro-4-fluoro-N-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]benzamide chemical structure, C18H19ClFN3O3S, CAS 886630-69-9
2-Chloro-4-fluoro-N-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]benzamide
CAS 886630-69-9C18H19ClFN3O3S
3,4,5-Trimethoxy-N-{4-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}benzamide chemical structure, C21H27N3O6S, CAS 879917-22-3
3,4,5-Trimethoxy-N-{4-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}benzamide
CAS 879917-22-3C21H27N3O6S
3-Isopropoxy-N-{4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl}benzamide chemical structure, C21H27N3O4S, CAS 909352-90-5
3-Isopropoxy-N-{4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl}benzamide
CAS 909352-90-5C21H27N3O4S
RN 9893 hydrochloride chemical structure, C21H24ClF3N4O5S, CAS 2109450-40-8
RN 9893 hydrochloride
CAS 2109450-40-8C21H24ClF3N4O5S
RN-9893 chemical structure, C21H23F3N4O5S, CAS 1803003-68-0
RN-9893
CAS 1803003-68-0C21H23F3N4O5S
4-(Pentafluoro-lambda6-sulfanyl)-N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]benzamide chemical structure, C20H24F5N3O3S2, CAS 1803003-65-7
4-(Pentafluoro-lambda6-sulfanyl)-N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]benzamide
CAS 1803003-65-7C20H24F5N3O3S2
Trpv4-IN-5 chemical structure, C20H22Cl3N3O3S, CAS 3046390-54-6
Trpv4-IN-5
CAS 3046390-54-6C20H22Cl3N3O3S