CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 21 atoms

140 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
140
With full pages
55
Scaffold SMILES

C(=NN1CCN(Cc2ccccc2)CC1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=NN1CCN(Cc2ccccc2)CC1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 140 chemicals

N-(4-Benzylpiperazin-1-yl)-1-(4-methylphenyl)methanimine chemical structure, C19H23N3
N-(4-Benzylpiperazin-1-yl)-1-(4-methylphenyl)methanimine
C19H23N3
1-(2-Chlorophenyl)-N-{4-[(2-chlorophenyl)methyl]piperazin-1-YL}methanimine chemical structure, C18H19Cl2N3, CAS 5788-37-4
1-(2-Chlorophenyl)-N-{4-[(2-chlorophenyl)methyl]piperazin-1-YL}methanimine
CAS 5788-37-4C18H19Cl2N3
N-(4-Benzylpiperazin-1-yl)-1-(4-tert-butylphenyl)methanimine chemical structure, C22H29N3, CAS 5784-91-8
N-(4-Benzylpiperazin-1-yl)-1-(4-tert-butylphenyl)methanimine
CAS 5784-91-8C22H29N3
N-(4-Benzylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)methanimine chemical structure, C21H27N3O3
N-(4-Benzylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)methanimine
C21H27N3O3
N-(4-Benzylpiperazin-1-yl)-1-(2,4,5-trimethoxyphenyl)methanimine chemical structure, C21H27N3O3, CAS 5783-99-3
N-(4-Benzylpiperazin-1-yl)-1-(2,4,5-trimethoxyphenyl)methanimine
CAS 5783-99-3C21H27N3O3
RefChem:381790 chemical structure, C20H24ClN3O2, CAS 5784-02-1
RefChem:381790
CAS 5784-02-1C20H24ClN3O2
2-[2-[[4-[(2,4-Dimethylphenyl)methyl]piperazin-1-yl]iminomethyl]phenoxy]acetic acid chemical structure, C22H27N3O3, CAS 6068-08-2
2-[2-[[4-[(2,4-Dimethylphenyl)methyl]piperazin-1-yl]iminomethyl]phenoxy]acetic acid
CAS 6068-08-2C22H27N3O3
N-[4-[(2,4-Dimethylphenyl)methyl]piperazin-1-yl]-1-(2-nitrophenyl)methanimine chemical structure, C20H24N4O2, CAS 6069-02-9
N-[4-[(2,4-Dimethylphenyl)methyl]piperazin-1-yl]-1-(2-nitrophenyl)methanimine
CAS 6069-02-9C20H24N4O2
1-(4-Bromophenyl)-N-[4-[(2,4-dimethylphenyl)methyl]piperazin-1-yl]methanimine chemical structure, C20H24BrN3, CAS 6069-49-4
1-(4-Bromophenyl)-N-[4-[(2,4-dimethylphenyl)methyl]piperazin-1-yl]methanimine
CAS 6069-49-4C20H24BrN3
4-[[4-[(2,4-Dimethylphenyl)methyl]piperazin-1-yl]iminomethyl]-N,N-dimethylaniline chemical structure, C22H30N4, CAS 6069-88-1
4-[[4-[(2,4-Dimethylphenyl)methyl]piperazin-1-yl]iminomethyl]-N,N-dimethylaniline
CAS 6069-88-1C22H30N4
N-(4-Benzylpiperazin-1-yl)-1-(4-ethoxyphenyl)methanimine chemical structure, C20H25N3O
N-(4-Benzylpiperazin-1-yl)-1-(4-ethoxyphenyl)methanimine
C20H25N3O
N-[4-[(2-Chlorophenyl)methyl]piperazin-1-yl]-1-(2-fluorophenyl)methanimine, hydrochloride chemical structure, C18H20Cl2FN3, CAS 471259-72-0
N-[4-[(2-Chlorophenyl)methyl]piperazin-1-yl]-1-(2-fluorophenyl)methanimine, hydrochloride
CAS 471259-72-0C18H20Cl2FN3
N-[4-[(2-Chlorophenyl)methyl]piperazin-1-yl]-1-(3-nitrophenyl)methanimine hydrochloride chemical structure, C18H20Cl2N4O2, CAS 5793-00-0
N-[4-[(2-Chlorophenyl)methyl]piperazin-1-yl]-1-(3-nitrophenyl)methanimine hydrochloride
CAS 5793-00-0C18H20Cl2N4O2
4-Benzyl-N-(4-tert-butylbenzylidene)-1-piperazinamine chemical structure, C22H29N3
4-Benzyl-N-(4-tert-butylbenzylidene)-1-piperazinamine
C22H29N3
4-Benzyl-N-(3,4,5-trimethoxybenzylidene)-1-piperazinamine chemical structure, C21H27N3O3, CAS 307328-32-1
4-Benzyl-N-(3,4,5-trimethoxybenzylidene)-1-piperazinamine
CAS 307328-32-1C21H27N3O3
4-(2-Chlorobenzyl)-N-[(1Z)-1-(3-nitrophenyl)ethylidene]piperazin-1-amine chemical structure, C19H21ClN4O2, CAS 307328-97-8
4-(2-Chlorobenzyl)-N-[(1Z)-1-(3-nitrophenyl)ethylidene]piperazin-1-amine
CAS 307328-97-8C19H21ClN4O2
(E)-N-(4-Benzylpiperazin-1-yl)-1-(2-ethoxyphenyl)methanimine chemical structure, C20H25N3O, CAS 307328-12-7
(E)-N-(4-Benzylpiperazin-1-yl)-1-(2-ethoxyphenyl)methanimine
CAS 307328-12-7C20H25N3O
N-(4-Benzylpiperazin-1-yl)-1-(2-bromophenyl)methanimine chemical structure, C18H20BrN3, CAS 304908-90-5
N-(4-Benzylpiperazin-1-yl)-1-(2-bromophenyl)methanimine
CAS 304908-90-5C18H20BrN3
4-Benzyl-N-(4-ethoxybenzylidene)-1-piperazinamine chemical structure, C20H25N3O, CAS 307328-30-9
4-Benzyl-N-(4-ethoxybenzylidene)-1-piperazinamine
CAS 307328-30-9C20H25N3O
(4-Benzyl-piperazin-1-yl)-(2-nitro-benzylidene)-amine chemical structure, C18H20N4O2, CAS 307328-21-8
(4-Benzyl-piperazin-1-yl)-(2-nitro-benzylidene)-amine
CAS 307328-21-8C18H20N4O2
(4-Benzyl-piperazin-1-yl)-(3-bromo-benzylidene)-amine chemical structure, C18H20BrN3, CAS 307328-10-5
(4-Benzyl-piperazin-1-yl)-(3-bromo-benzylidene)-amine
CAS 307328-10-5C18H20BrN3
(4-Benzyl-piperazin-1-yl)-(4-chloro-benzylidene)-amine chemical structure, C18H20ClN3, CAS 304908-96-1
(4-Benzyl-piperazin-1-yl)-(4-chloro-benzylidene)-amine
CAS 304908-96-1C18H20ClN3
4-(2-Chlorobenzyl)-N-(2,5-dimethoxybenzylidene)piperazin-1-amine chemical structure, C20H24ClN3O2, CAS 307328-68-3
4-(2-Chlorobenzyl)-N-(2,5-dimethoxybenzylidene)piperazin-1-amine
CAS 307328-68-3C20H24ClN3O2
4-(2-Chlorobenzyl)-N-(2-chlorobenzylidene)-1-piperazinamine chemical structure, C18H19Cl2N3
4-(2-Chlorobenzyl)-N-(2-chlorobenzylidene)-1-piperazinamine
C18H19Cl2N3