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Murcko scaffold

Ring system with 3 rings and 24 atoms

205 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
205
With full pages
18
Scaffold SMILES

O=C(Nc1ccccc1)C1CCN(S(=O)(=O)c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)C1CCN(S(=O)(=O)c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 205 chemicals

N-(4-Hydroxyphenyl)-1-(4-methylphenyl)sulfonylpiperidine-4-carboxamide chemical structure, C19H22N2O4S, CAS 667902-17-2
N-(4-Hydroxyphenyl)-1-(4-methylphenyl)sulfonylpiperidine-4-carboxamide
CAS 667902-17-2C19H22N2O4S
N-(2-Hydroxyphenyl)-1-(4-methylphenyl)sulfonylpiperidine-4-carboxamide chemical structure, C19H22N2O4S, CAS 667902-18-3
N-(2-Hydroxyphenyl)-1-(4-methylphenyl)sulfonylpiperidine-4-carboxamide
CAS 667902-18-3C19H22N2O4S
N-(3-Chloro-2-methylphenyl)-1-(4-methylphenyl)sulfonylpiperidine-4-carboxamide chemical structure, C20H23ClN2O3S, CAS 433966-56-4
N-(3-Chloro-2-methylphenyl)-1-(4-methylphenyl)sulfonylpiperidine-4-carboxamide
CAS 433966-56-4C20H23ClN2O3S
1-(Benzenesulfonyl)-N-(3-methylsulfanylphenyl)piperidine-4-carboxamide chemical structure, C19H22N2O3S2, CAS 433688-98-3
1-(Benzenesulfonyl)-N-(3-methylsulfanylphenyl)piperidine-4-carboxamide
CAS 433688-98-3C19H22N2O3S2
1-(Benzenesulfonyl)-N-(2,4,5-trichlorophenyl)piperidine-4-carboxamide chemical structure, C18H17Cl3N2O3S, CAS 433948-81-3
1-(Benzenesulfonyl)-N-(2,4,5-trichlorophenyl)piperidine-4-carboxamide
CAS 433948-81-3C18H17Cl3N2O3S
N-(4-Iodophenyl)-1-(4-methoxyphenyl)sulfonylpiperidine-4-carboxamide chemical structure, C19H21IN2O4S, CAS 444785-94-8
N-(4-Iodophenyl)-1-(4-methoxyphenyl)sulfonylpiperidine-4-carboxamide
CAS 444785-94-8C19H21IN2O4S
N-(3-Bromophenyl)-1-(2,5-dichlorophenyl)sulfonylpiperidine-4-carboxamide chemical structure, C18H17BrCl2N2O3S, CAS 593259-17-7
N-(3-Bromophenyl)-1-(2,5-dichlorophenyl)sulfonylpiperidine-4-carboxamide
CAS 593259-17-7C18H17BrCl2N2O3S
1-[(4-Methoxyphenyl)sulfonyl]-N-[4-(trifluoromethyl)phenyl]-4-piperidinecarboxamide chemical structure, C20H21F3N2O4S, CAS 593263-39-9
1-[(4-Methoxyphenyl)sulfonyl]-N-[4-(trifluoromethyl)phenyl]-4-piperidinecarboxamide
CAS 593263-39-9C20H21F3N2O4S
N-(2,6-Difluorophenyl)-1-(4-methoxyphenyl)sulfonylpiperidine-4-carboxamide chemical structure, C19H20F2N2O4S, CAS 593263-38-8
N-(2,6-Difluorophenyl)-1-(4-methoxyphenyl)sulfonylpiperidine-4-carboxamide
CAS 593263-38-8C19H20F2N2O4S
1-(2,5-Dichlorophenyl)sulfonyl-N-[4-(trifluoromethyl)phenyl]piperidine-4-carboxamide chemical structure, C19H17Cl2F3N2O3S, CAS 593263-40-2
1-(2,5-Dichlorophenyl)sulfonyl-N-[4-(trifluoromethyl)phenyl]piperidine-4-carboxamide
CAS 593263-40-2C19H17Cl2F3N2O3S
1-(4-Methylphenyl)sulfonyl-N-[4-(trifluoromethyl)phenyl]piperidine-4-carboxamide chemical structure, C20H21F3N2O3S, CAS 664360-50-3
1-(4-Methylphenyl)sulfonyl-N-[4-(trifluoromethyl)phenyl]piperidine-4-carboxamide
CAS 664360-50-3C20H21F3N2O3S
N-(4-Acetamidophenyl)-1-(4-methylphenyl)sulfonylpiperidine-4-carboxamide chemical structure, C21H25N3O4S, CAS 516453-56-8
N-(4-Acetamidophenyl)-1-(4-methylphenyl)sulfonylpiperidine-4-carboxamide
CAS 516453-56-8C21H25N3O4S
1-(3,4-Dimethoxyphenyl)sulfonyl-N-(4-ethoxyphenyl)piperidine-4-carboxamide chemical structure, C22H28N2O6S, CAS 433688-24-5
1-(3,4-Dimethoxyphenyl)sulfonyl-N-(4-ethoxyphenyl)piperidine-4-carboxamide
CAS 433688-24-5C22H28N2O6S
1-(3,4-Dimethoxyphenyl)sulfonyl-N-(4-propan-2-ylphenyl)piperidine-4-carboxamide chemical structure, C23H30N2O5S, CAS 591226-71-0
1-(3,4-Dimethoxyphenyl)sulfonyl-N-(4-propan-2-ylphenyl)piperidine-4-carboxamide
CAS 591226-71-0C23H30N2O5S
1-(3,4-Dimethoxyphenyl)sulfonyl-N-(2-ethylphenyl)piperidine-4-carboxamide chemical structure, C22H28N2O5S, CAS 433688-12-1
1-(3,4-Dimethoxyphenyl)sulfonyl-N-(2-ethylphenyl)piperidine-4-carboxamide
CAS 433688-12-1C22H28N2O5S
1-(3,4-Dimethoxyphenyl)sulfonyl-N-(2,4-dimethylphenyl)piperidine-4-carboxamide chemical structure, C22H28N2O5S, CAS 433694-72-5
1-(3,4-Dimethoxyphenyl)sulfonyl-N-(2,4-dimethylphenyl)piperidine-4-carboxamide
CAS 433694-72-5C22H28N2O5S
N-(3-Chlorophenyl)-1-(3,4-dimethoxyphenyl)sulfonylpiperidine-4-carboxamide chemical structure, C20H23ClN2O5S, CAS 433705-65-8
N-(3-Chlorophenyl)-1-(3,4-dimethoxyphenyl)sulfonylpiperidine-4-carboxamide
CAS 433705-65-8C20H23ClN2O5S
N-(3-Chloro-4-methoxyphenyl)-1-(4-methylphenyl)sulfonylpiperidine-4-carboxamide chemical structure, C20H23ClN2O4S, CAS 433967-67-0
N-(3-Chloro-4-methoxyphenyl)-1-(4-methylphenyl)sulfonylpiperidine-4-carboxamide
CAS 433967-67-0C20H23ClN2O4S
N-(3-Chloro-4-methoxyphenyl)-1-(4-fluorophenyl)sulfonylpiperidine-4-carboxamide chemical structure, C19H20ClFN2O4S, CAS 508187-61-9
N-(3-Chloro-4-methoxyphenyl)-1-(4-fluorophenyl)sulfonylpiperidine-4-carboxamide
CAS 508187-61-9C19H20ClFN2O4S
N-(2,3-Dimethylphenyl)-1-(4-methoxyphenyl)sulfonylpiperidine-4-carboxamide chemical structure, C21H26N2O4S, CAS 510722-47-1
N-(2,3-Dimethylphenyl)-1-(4-methoxyphenyl)sulfonylpiperidine-4-carboxamide
CAS 510722-47-1C21H26N2O4S
N-(4-Isopropylphenyl)-1-((4-methoxyphenyl)sulfonyl)piperidine-4-carboxamide chemical structure, C22H28N2O4S, CAS 593258-66-3
N-(4-Isopropylphenyl)-1-((4-methoxyphenyl)sulfonyl)piperidine-4-carboxamide
CAS 593258-66-3C22H28N2O4S
N-(4-Fluorophenyl)-1-(4-methoxybenzenesulfonyl)piperidine-4-carboxamide chemical structure, C19H21FN2O4S, CAS 593258-68-5
N-(4-Fluorophenyl)-1-(4-methoxybenzenesulfonyl)piperidine-4-carboxamide
CAS 593258-68-5C19H21FN2O4S
N-(2-Methoxyphenyl)-1-((4-methoxyphenyl)sulfonyl)piperidine-4-carboxamide chemical structure, C20H24N2O5S, CAS 510722-61-9
N-(2-Methoxyphenyl)-1-((4-methoxyphenyl)sulfonyl)piperidine-4-carboxamide
CAS 510722-61-9C20H24N2O5S
N-(4-Methoxyphenyl)-1-(4-methoxyphenyl)sulfonylpiperidine-4-carboxamide chemical structure, C20H24N2O5S, CAS 460046-50-8
N-(4-Methoxyphenyl)-1-(4-methoxyphenyl)sulfonylpiperidine-4-carboxamide
CAS 460046-50-8C20H24N2O5S