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Murcko scaffold

N-[4-(1-Piperidinylsulfonyl)phenyl]benzamide scaffold

60 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
60
With full pages
14
Scaffold SMILES

O=C(Nc1ccc(S(=O)(=O)N2CCCCC2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-[4-(1-Piperidinylsulfonyl)phenyl]benzamide page
Murcko scaffold O=C(Nc1ccc(S(=O)(=O)N2CCCCC2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 60 chemicals

N-[4-(1-Piperidinylsulfonyl)phenyl]benzamide chemical structure, C18H20N2O3S, CAS 332039-81-3
N-[4-(1-Piperidinylsulfonyl)phenyl]benzamide
CAS 332039-81-3C18H20N2O3S
4-Chloro-N-[4-(1-piperidinylsulfonyl)phenyl]benzamide chemical structure, C18H19ClN2O3S, CAS 316154-84-4
4-Chloro-N-[4-(1-piperidinylsulfonyl)phenyl]benzamide
CAS 316154-84-4C18H19ClN2O3S
2,4-Dichloro-N-[4-(piperidin-1-ylsulfonyl)phenyl]benzamide chemical structure, C18H18Cl2N2O3S, CAS 316154-83-3
2,4-Dichloro-N-[4-(piperidin-1-ylsulfonyl)phenyl]benzamide
CAS 316154-83-3C18H18Cl2N2O3S
4-Fluoro-N-(4-piperidin-1-ylsulfonylphenyl)benzamide chemical structure, C18H19FN2O3S, CAS 316154-80-0
4-Fluoro-N-(4-piperidin-1-ylsulfonylphenyl)benzamide
CAS 316154-80-0C18H19FN2O3S
3-Iodo-4-methoxy-N-[4-(1-piperidinylsulfonyl)phenyl]benzamide chemical structure, C19H21IN2O4S, CAS 328025-35-0
3-Iodo-4-methoxy-N-[4-(1-piperidinylsulfonyl)phenyl]benzamide
CAS 328025-35-0C19H21IN2O4S
4-Methyl-N-{4-[(4-methyl-1-piperidinyl)sulfonyl]phenyl}benzamide chemical structure, C20H24N2O3S, CAS 315670-59-8
4-Methyl-N-{4-[(4-methyl-1-piperidinyl)sulfonyl]phenyl}benzamide
CAS 315670-59-8C20H24N2O3S
2-Methyl-N-{4-[(4-methyl-1-piperidinyl)sulfonyl]phenyl}benzamide chemical structure, C20H24N2O3S, CAS 349620-60-6
2-Methyl-N-{4-[(4-methyl-1-piperidinyl)sulfonyl]phenyl}benzamide
CAS 349620-60-6C20H24N2O3S
4-Chloro-N-{4-[(4-methyl-1-piperidinyl)sulfonyl]phenyl}benzamide chemical structure, C19H21ClN2O3S, CAS 349620-88-8
4-Chloro-N-{4-[(4-methyl-1-piperidinyl)sulfonyl]phenyl}benzamide
CAS 349620-88-8C19H21ClN2O3S
2-Nitro-N-[4-(1-piperidinylsulfonyl)phenyl]benzamide chemical structure, C18H19N3O5S, CAS 316154-82-2
2-Nitro-N-[4-(1-piperidinylsulfonyl)phenyl]benzamide
CAS 316154-82-2C18H19N3O5S
3-Nitro-N-(4-piperidin-1-ylsulfonylphenyl)benzamide chemical structure, C18H19N3O5S, CAS 316154-85-5
3-Nitro-N-(4-piperidin-1-ylsulfonylphenyl)benzamide
CAS 316154-85-5C18H19N3O5S
N-{4-[(4-Methyl-1-piperidinyl)sulfonyl]phenyl}-4-nitrobenzamide chemical structure, C19H21N3O5S, CAS 315249-40-2
N-{4-[(4-Methyl-1-piperidinyl)sulfonyl]phenyl}-4-nitrobenzamide
CAS 315249-40-2C19H21N3O5S
N-[4-(4-Methylpiperidin-1-yl)sulfonylphenyl]-3-nitrobenzamide chemical structure, C19H21N3O5S, CAS 349620-92-4
N-[4-(4-Methylpiperidin-1-yl)sulfonylphenyl]-3-nitrobenzamide
CAS 349620-92-4C19H21N3O5S
3,4,5-Trimethoxy-N-{4-[(4-methylpiperidin-1-yl)sulfonyl]phenyl}benzamide chemical structure, C22H28N2O6S, CAS 356076-40-9
3,4,5-Trimethoxy-N-{4-[(4-methylpiperidin-1-yl)sulfonyl]phenyl}benzamide
CAS 356076-40-9C22H28N2O6S
3-Bromo-4-methoxy-N-[4-(piperidin-1-ylsulfonyl)phenyl]benzamide chemical structure, C19H21BrN2O4S, CAS 356550-32-8
3-Bromo-4-methoxy-N-[4-(piperidin-1-ylsulfonyl)phenyl]benzamide
CAS 356550-32-8C19H21BrN2O4S
3-Bromo-4-methoxy-N-(4-((4-methylpiperidin-1-yl)sulfonyl)phenyl)benzamide chemical structure, C20H23BrN2O4S, CAS 356550-37-3
3-Bromo-4-methoxy-N-(4-((4-methylpiperidin-1-yl)sulfonyl)phenyl)benzamide
CAS 356550-37-3C20H23BrN2O4S
3-Bromo-4-methyl-N-[4-(4-methylpiperidin-1-yl)sulfonylphenyl]benzamide chemical structure, C20H23BrN2O3S, CAS 443296-76-2
3-Bromo-4-methyl-N-[4-(4-methylpiperidin-1-yl)sulfonylphenyl]benzamide
CAS 443296-76-2C20H23BrN2O3S
2,4-Dimethoxy-N-[4-(4-methylpiperidin-1-yl)sulfonylphenyl]benzamide chemical structure, C21H26N2O5S, CAS 510740-57-5
2,4-Dimethoxy-N-[4-(4-methylpiperidin-1-yl)sulfonylphenyl]benzamide
CAS 510740-57-5C21H26N2O5S
2-Methoxy-N-[4-(4-methylpiperidin-1-yl)sulfonylphenyl]-4-methylsulfanylbenzamide chemical structure, C21H26N2O4S2, CAS 510763-51-6
2-Methoxy-N-[4-(4-methylpiperidin-1-yl)sulfonylphenyl]-4-methylsulfanylbenzamide
CAS 510763-51-6C21H26N2O4S2
3-Fluoro-N-[4-(4-methylpiperidin-1-yl)sulfonylphenyl]benzamide chemical structure, C19H21FN2O3S, CAS 510763-91-4
3-Fluoro-N-[4-(4-methylpiperidin-1-yl)sulfonylphenyl]benzamide
CAS 510763-91-4C19H21FN2O3S
2-Fluoro-N-(4-piperidin-1-ylsulfonylphenyl)benzamide chemical structure, C18H19FN2O3S, CAS 444077-64-9
2-Fluoro-N-(4-piperidin-1-ylsulfonylphenyl)benzamide
CAS 444077-64-9C18H19FN2O3S
4-Ethoxy-N-(4-piperidin-1-ylsulfonylphenyl)benzamide chemical structure, C20H24N2O4S, CAS 600163-55-1
4-Ethoxy-N-(4-piperidin-1-ylsulfonylphenyl)benzamide
CAS 600163-55-1C20H24N2O4S
5-Chloro-2-methoxy-N-(4-piperidin-1-ylsulfonylphenyl)benzamide chemical structure, C19H21ClN2O4S, CAS 600148-63-8
5-Chloro-2-methoxy-N-(4-piperidin-1-ylsulfonylphenyl)benzamide
CAS 600148-63-8C19H21ClN2O4S
2-Methoxy-4-methylsulfanyl-N-(4-piperidin-1-ylsulfonylphenyl)benzamide chemical structure, C20H24N2O4S2, CAS 600149-04-0
2-Methoxy-4-methylsulfanyl-N-(4-piperidin-1-ylsulfonylphenyl)benzamide
CAS 600149-04-0C20H24N2O4S2
3-(2-Methylpropanoylamino)-N-(4-piperidin-1-ylsulfonylphenyl)benzamide chemical structure, C22H27N3O4S, CAS 600640-78-6
3-(2-Methylpropanoylamino)-N-(4-piperidin-1-ylsulfonylphenyl)benzamide
CAS 600640-78-6C22H27N3O4S