CompoundList
Sign in
Murcko scaffold

1-Phenyl-6,7-dihydro-5H-indol-4-one scaffold

77 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
77
With full pages
5
Scaffold SMILES

O=C1CCCc2c1ccn2-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Phenyl-6,7-dihydro-5H-indol-4-one page
Murcko scaffold O=C1CCCc2c1ccn2-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 77 chemicals

1-Phenyl-6,7-dihydro-5H-indol-4-one chemical structure, C14H13NO, CAS 23870-03-3
1-Phenyl-6,7-dihydro-5H-indol-4-one
CAS 23870-03-3C14H13NO
4-(2,6,6-Trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)benzamide chemical structure, C18H20N2O2, CAS 497061-30-0
4-(2,6,6-Trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)benzamide
CAS 497061-30-0C18H20N2O2
1-(4-Chlorophenyl)-2,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indol-4-one chemical structure, C17H18ClNO, CAS 163083-11-2
1-(4-Chlorophenyl)-2,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indol-4-one
CAS 163083-11-2C17H18ClNO
1-(4-Bromophenyl)-2,6,6-trimethyl-3-(2,2,2-trichloroethyl)-5,7-dihydroindol-4-one chemical structure, C19H19BrCl3NO, CAS 426823-92-9
1-(4-Bromophenyl)-2,6,6-trimethyl-3-(2,2,2-trichloroethyl)-5,7-dihydroindol-4-one
CAS 426823-92-9C19H19BrCl3NO
1-(3-Methoxyphenyl)-2,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indol-4-one chemical structure, C18H21NO2, CAS 344276-05-7
1-(3-Methoxyphenyl)-2,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indol-4-one
CAS 344276-05-7C18H21NO2
3-Bromo-2-methyl-1-(4-methylphenyl)-4,5,6,7-tetrahydro-1H-indol-4-one chemical structure, C16H16BrNO, CAS 327082-74-6
3-Bromo-2-methyl-1-(4-methylphenyl)-4,5,6,7-tetrahydro-1H-indol-4-one
CAS 327082-74-6C16H16BrNO
2-Methyl-1-[3-(trifluoromethyl)phenyl]-4,5,6,7-tetrahydro-1H-indol-4-one chemical structure, C16H14F3NO, CAS 327085-04-1
2-Methyl-1-[3-(trifluoromethyl)phenyl]-4,5,6,7-tetrahydro-1H-indol-4-one
CAS 327085-04-1C16H14F3NO
N-[2-(Diethylamino)ethyl]-4-(2-methyl-4-oxo-6,7-dihydro-5H-indol-1-yl)benzamide chemical structure, C22H29N3O2, CAS 380427-25-8
N-[2-(Diethylamino)ethyl]-4-(2-methyl-4-oxo-6,7-dihydro-5H-indol-1-yl)benzamide
CAS 380427-25-8C22H29N3O2
2-Methyl-1-p-tolyl-1,5,6,7-tetrahydro-indol-4-one chemical structure, C16H17NO, CAS 326916-10-3
2-Methyl-1-p-tolyl-1,5,6,7-tetrahydro-indol-4-one
CAS 326916-10-3C16H17NO
1-(3,4-Dichlorophenyl)-2,6,6-trimethyl-5,7-dihydroindol-4-one chemical structure, C17H17Cl2NO, CAS 627836-40-2
1-(3,4-Dichlorophenyl)-2,6,6-trimethyl-5,7-dihydroindol-4-one
CAS 627836-40-2C17H17Cl2NO
1-(3,5-Difluorophenyl)-2,6,6-trimethyl-5,7-dihydroindol-4-one chemical structure, C17H17F2NO, CAS 1022324-58-8
1-(3,5-Difluorophenyl)-2,6,6-trimethyl-5,7-dihydroindol-4-one
CAS 1022324-58-8C17H17F2NO
1-(4-Fluorophenyl)-2,6,6-trimethyl-5,7-dihydroindol-4-one chemical structure, C17H18FNO, CAS 96757-76-5
1-(4-Fluorophenyl)-2,6,6-trimethyl-5,7-dihydroindol-4-one
CAS 96757-76-5C17H18FNO
1-(3,5-Dichloro-4-hydroxyphenyl)-2,6,6-trimethyl-5,6,7-trihydroindol-4-one chemical structure, C17H17Cl2NO2, CAS 1022530-75-1
1-(3,5-Dichloro-4-hydroxyphenyl)-2,6,6-trimethyl-5,6,7-trihydroindol-4-one
CAS 1022530-75-1C17H17Cl2NO2
3-(2,6,6-Trimethyl-4-oxo-5,7-dihydroindol-1-yl)benzonitrile chemical structure, C18H18N2O, CAS 1022580-03-5
3-(2,6,6-Trimethyl-4-oxo-5,7-dihydroindol-1-yl)benzonitrile
CAS 1022580-03-5C18H18N2O
1-(4-Chloro-3-nitrophenyl)-2,6,6-trimethyl-5,7-dihydroindol-4-one chemical structure, C17H17ClN2O3, CAS 1022511-28-9
1-(4-Chloro-3-nitrophenyl)-2,6,6-trimethyl-5,7-dihydroindol-4-one
CAS 1022511-28-9C17H17ClN2O3
2,2,2-Trifluoro-N-[4-(2,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)phenyl]acetamide chemical structure, C19H19F3N2O2, CAS 1022730-26-2
2,2,2-Trifluoro-N-[4-(2,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)phenyl]acetamide
CAS 1022730-26-2C19H19F3N2O2
1-(3-Chlorophenyl)-2,6,6-trimethyl-5,7-dihydroindol-4-one chemical structure, C17H18ClNO, CAS 164226-66-8
1-(3-Chlorophenyl)-2,6,6-trimethyl-5,7-dihydroindol-4-one
CAS 164226-66-8C17H18ClNO
1-(4-Aminophenyl)-2,6,6-trimethyl-5,6,7-trihydroindol-4-one chemical structure, C17H20N2O, CAS 865375-66-2
1-(4-Aminophenyl)-2,6,6-trimethyl-5,6,7-trihydroindol-4-one
CAS 865375-66-2C17H20N2O
4-(2,6,6-Trimethyl-4-oxo-5,7-dihydroindol-1-yl)benzonitrile chemical structure, C18H18N2O, CAS 1022585-37-0
4-(2,6,6-Trimethyl-4-oxo-5,7-dihydroindol-1-yl)benzonitrile
CAS 1022585-37-0C18H18N2O
1-(3-Chlorophenyl)-2,6-dimethyl-6,7-dihydro-5H-indol-4-one chemical structure, C16H16ClNO, CAS 1022879-87-3
1-(3-Chlorophenyl)-2,6-dimethyl-6,7-dihydro-5H-indol-4-one
CAS 1022879-87-3C16H16ClNO
1-(4-Chloro-3-nitrophenyl)-2,6-dimethyl-5,6,7-trihydroindol-4-one chemical structure, C16H15ClN2O3, CAS 1022675-06-4
1-(4-Chloro-3-nitrophenyl)-2,6-dimethyl-5,6,7-trihydroindol-4-one
CAS 1022675-06-4C16H15ClN2O3
1-(4-Methoxyphenyl)-2,6,6-trimethyl-4,5,6,7-tetrahydro-1H-indol-4-one chemical structure, C18H21NO2, CAS 163083-10-1
1-(4-Methoxyphenyl)-2,6,6-trimethyl-4,5,6,7-tetrahydro-1H-indol-4-one
CAS 163083-10-1C18H21NO2
1-(3,5-Dichlorophenyl)-2,6,6-trimethyl-5,7-dihydroindol-4-one chemical structure, C17H17Cl2NO, CAS 627836-66-2
1-(3,5-Dichlorophenyl)-2,6,6-trimethyl-5,7-dihydroindol-4-one
CAS 627836-66-2C17H17Cl2NO
1-(3,5-Dichlorophenyl)-2,6-dimethyl-6,7-dihydro-5H-indol-4-one chemical structure, C16H15Cl2NO, CAS 1022480-78-9
1-(3,5-Dichlorophenyl)-2,6-dimethyl-6,7-dihydro-5H-indol-4-one
CAS 1022480-78-9C16H15Cl2NO