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Murcko scaffold

Ring system with 2 rings and 13 atoms

159 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
159
With full pages
23
Scaffold SMILES

c1ccc(CC2CCOCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CC2CCOCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 159 chemicals

3-(2,2-Dimethyloxan-4-yl)-3-phenylpropanoic acid chemical structure, C16H22O3, CAS 331430-39-8
3-(2,2-Dimethyloxan-4-yl)-3-phenylpropanoic acid
CAS 331430-39-8C16H22O3
3-(2,2-Dimethyloxan-4-yl)-3-(4-methoxyphenyl)propanenitrile chemical structure, C17H23NO2, CAS 309270-87-9
3-(2,2-Dimethyloxan-4-yl)-3-(4-methoxyphenyl)propanenitrile
CAS 309270-87-9C17H23NO2
Ethyl 2-cyano-3-(2,2-dimethyloxan-4-yl)-3-(2-methoxyphenyl)propanoate chemical structure, C20H27NO4, CAS 303953-41-5
Ethyl 2-cyano-3-(2,2-dimethyloxan-4-yl)-3-(2-methoxyphenyl)propanoate
CAS 303953-41-5C20H27NO4
3-(2,2-Dimethyloxan-4-yl)-3-(2-methoxyphenyl)propanenitrile chemical structure, C17H23NO2, CAS 5936-39-0
3-(2,2-Dimethyloxan-4-yl)-3-(2-methoxyphenyl)propanenitrile
CAS 5936-39-0C17H23NO2
3-(2,2-Dimethyloxan-4-yl)-3-(4-methylphenyl)propanenitrile chemical structure, C17H23NO, CAS 300835-16-9
3-(2,2-Dimethyloxan-4-yl)-3-(4-methylphenyl)propanenitrile
CAS 300835-16-9C17H23NO
3-(2,2-Dimethyloxan-4-yl)-3-(2-methoxyphenyl)propan-1-amine chemical structure, C17H27NO2, CAS 350993-70-3
3-(2,2-Dimethyloxan-4-yl)-3-(2-methoxyphenyl)propan-1-amine
CAS 350993-70-3C17H27NO2
3-(2,2-Dimethyloxan-4-yl)-3-(2-methoxyphenyl)propanoic acid chemical structure, C17H24O4, CAS 423736-99-6
3-(2,2-Dimethyloxan-4-yl)-3-(2-methoxyphenyl)propanoic acid
CAS 423736-99-6C17H24O4
3-(2,2-Dimethyloxan-4-yl)-3-phenyl-N,N-dipropylpropanamide chemical structure, C22H35NO2, CAS 671763-71-6
3-(2,2-Dimethyloxan-4-yl)-3-phenyl-N,N-dipropylpropanamide
CAS 671763-71-6C22H35NO2
Cambridge id 5936386 chemical structure, C16H21NO, CAS 109878-47-9
Cambridge id 5936386
CAS 109878-47-9C16H21NO
Ethyl 2-cyano-3-(2,2-dimethyltetrahydro-2H-pyran-4-yl)-3-(4-fluorophenyl)propanoate chemical structure, C19H24FNO3, CAS 1005060-47-8
Ethyl 2-cyano-3-(2,2-dimethyltetrahydro-2H-pyran-4-yl)-3-(4-fluorophenyl)propanoate
CAS 1005060-47-8C19H24FNO3
(4-Benzyl-2,2-dimethyl-tetrahydro-pyran-4-yl)-acetic acid chemical structure, C16H22O3, CAS 109878-51-5
(4-Benzyl-2,2-dimethyl-tetrahydro-pyran-4-yl)-acetic acid
CAS 109878-51-5C16H22O3
3-(2,2-Dimethyl-tetrahydro-pyran-4-yl)-3-phenyl-propylamine chemical structure, C16H25NO, CAS 337311-00-9
3-(2,2-Dimethyl-tetrahydro-pyran-4-yl)-3-phenyl-propylamine
CAS 337311-00-9C16H25NO
3-(2,2-Dimethyl-tetrahydro-pyran-4-yl)-3-(4-fluoro-phenyl)-propylamine chemical structure, C16H24FNO, CAS 363620-89-7
3-(2,2-Dimethyl-tetrahydro-pyran-4-yl)-3-(4-fluoro-phenyl)-propylamine
CAS 363620-89-7C16H24FNO
3-(2,2-Dimethyloxan-4-yl)-3-phenylpropanenitrile chemical structure, C16H21NO, CAS 303728-91-8
3-(2,2-Dimethyloxan-4-yl)-3-phenylpropanenitrile
CAS 303728-91-8C16H21NO
2-(4-Benzyl-2,2-dimethyl-tetrahydro-pyran-4-yl)-ethylamine chemical structure, C16H25NO, CAS 126318-00-1
2-(4-Benzyl-2,2-dimethyl-tetrahydro-pyran-4-yl)-ethylamine
CAS 126318-00-1C16H25NO
3-(2,2-Dimethyloxan-4-yl)-3-(4-methoxyphenyl)propanoic acid chemical structure, C17H24O4, CAS 423736-92-9
3-(2,2-Dimethyloxan-4-yl)-3-(4-methoxyphenyl)propanoic acid
CAS 423736-92-9C17H24O4
2-[4-[(2-Chlorophenyl)methyl]-2,2-dimethyloxan-4-yl]acetonitrile chemical structure, C16H20ClNO, CAS 861147-19-5
2-[4-[(2-Chlorophenyl)methyl]-2,2-dimethyloxan-4-yl]acetonitrile
CAS 861147-19-5C16H20ClNO
2-[4-[(2-Chlorophenyl)methyl]-2,2-dimethyloxan-4-yl]ethanamine chemical structure, C16H24ClNO, CAS 861148-09-6
2-[4-[(2-Chlorophenyl)methyl]-2,2-dimethyloxan-4-yl]ethanamine
CAS 861148-09-6C16H24ClNO
4-Benzyl-2,2-dimethyltetrahydro-2H-pyran-4-carboxylic acid chemical structure, C15H20O3, CAS 374702-03-1
4-Benzyl-2,2-dimethyltetrahydro-2H-pyran-4-carboxylic acid
CAS 374702-03-1C15H20O3
4-Benzyltetrahydropyran-4-ol chemical structure, C12H16O2, CAS 189019-31-6
4-Benzyltetrahydropyran-4-ol
CAS 189019-31-6C12H16O2
4-(Bromophenylmethyl)tetrahydro-2H-pyran chemical structure, C12H15BrO, CAS 1342366-13-5
4-(Bromophenylmethyl)tetrahydro-2H-pyran
CAS 1342366-13-5C12H15BrO
4-(Tetrahydro-pyran-4-ylmethyl)-phenylamine chemical structure, C12H17NO, CAS 1780609-31-5
4-(Tetrahydro-pyran-4-ylmethyl)-phenylamine
CAS 1780609-31-5C12H17NO
4-Benzyloxan-4-amine chemical structure, C12H17NO, CAS 1017134-27-8
4-Benzyloxan-4-amine
CAS 1017134-27-8C12H17NO
4-[(2-Fluorophenyl)methyl]oxan-4-amine chemical structure, C12H16FNO, CAS 1017134-31-4
4-[(2-Fluorophenyl)methyl]oxan-4-amine
CAS 1017134-31-4C12H16FNO