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Murcko scaffold

2-(Phenylamino)-4,5-dihydro-1,3-thiazol-4-one scaffold

97 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
97
With full pages
49
Scaffold SMILES

O=C1CSC(=Nc2ccccc2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Phenylamino)-4,5-dihydro-1,3-thiazol-4-one page
Murcko scaffold O=C1CSC(=Nc2ccccc2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 97 chemicals

(2E)-2-(Phenylimino)-3-propyl-1,3-thiazolidin-4-one chemical structure, C12H14N2OS, CAS 63543-89-5
(2E)-2-(Phenylimino)-3-propyl-1,3-thiazolidin-4-one
CAS 63543-89-5C12H14N2OS
2-[(4-Hydroxyphenyl)(methyl)amino]-1,3-thiazol-4(5H)-one chemical structure, C10H10N2O2S, CAS 320393-90-6
2-[(4-Hydroxyphenyl)(methyl)amino]-1,3-thiazol-4(5H)-one
CAS 320393-90-6C10H10N2O2S
3-[(3-Methyl-4-oxo-2-thiazolidinylidene)amino]benzoic acid chemical structure, C11H10N2O3S, CAS 436811-29-9
3-[(3-Methyl-4-oxo-2-thiazolidinylidene)amino]benzoic acid
CAS 436811-29-9C11H10N2O3S
4-((3-Allyl-4-oxo-1,3-thiazolidin-2-ylidene)amino)benzoic acid chemical structure, C13H12N2O3S, CAS 303093-13-2
4-((3-Allyl-4-oxo-1,3-thiazolidin-2-ylidene)amino)benzoic acid
CAS 303093-13-2C13H12N2O3S
2-[(4-Methoxyphenyl)imino]-3-methyl-1,3-thiazolidin-4-one chemical structure, C11H12N2O2S, CAS 63500-81-2
2-[(4-Methoxyphenyl)imino]-3-methyl-1,3-thiazolidin-4-one
CAS 63500-81-2C11H12N2O2S
(2E)-3-Methyl-2-[(4-methylphenyl)imino]-1,3-thiazolidin-4-one chemical structure, C11H12N2OS, CAS 1346011-46-8
(2E)-3-Methyl-2-[(4-methylphenyl)imino]-1,3-thiazolidin-4-one
CAS 1346011-46-8C11H12N2OS
(Z)-3-(Pentylsulfonyl)-2-(phenylimino)thiazolidin-4-one chemical structure, C14H18N2O3S2, CAS 469876-27-5
(Z)-3-(Pentylsulfonyl)-2-(phenylimino)thiazolidin-4-one
CAS 469876-27-5C14H18N2O3S2
2-[(4-Bromophenyl)imino]-3-methyl-1,3-thiazolidin-4-one chemical structure, C10H9BrN2OS, CAS 63500-83-4
2-[(4-Bromophenyl)imino]-3-methyl-1,3-thiazolidin-4-one
CAS 63500-83-4C10H9BrN2OS
{2-[(4-Hydroxyphenyl)(methyl)amino]-4-oxo-4,5-dihydro-1,3-thiazol-5-yl}acetic acid chemical structure, C12H12N2O4S, CAS 307545-41-1
{2-[(4-Hydroxyphenyl)(methyl)amino]-4-oxo-4,5-dihydro-1,3-thiazol-5-yl}acetic acid
CAS 307545-41-1C12H12N2O4S
{3-Allyl-2-[(4-methylphenyl)imino]-4-oxo-1,3-thiazolidin-5-yl}acetic acid chemical structure, C15H16N2O3S, CAS 540761-83-9
{3-Allyl-2-[(4-methylphenyl)imino]-4-oxo-1,3-thiazolidin-5-yl}acetic acid
CAS 540761-83-9C15H16N2O3S
Ethyl 4-[(3-methyl-4-oxo-1,3-thiazolidin-2-ylidene)amino]benzoate chemical structure, C13H14N2O3S, CAS 292641-33-9
Ethyl 4-[(3-methyl-4-oxo-1,3-thiazolidin-2-ylidene)amino]benzoate
CAS 292641-33-9C13H14N2O3S
Methyl 4-[(3-methyl-4-oxo-1,3-thiazolidin-2-ylidene)amino]benzoate chemical structure, C12H12N2O3S, CAS 443878-33-9
Methyl 4-[(3-methyl-4-oxo-1,3-thiazolidin-2-ylidene)amino]benzoate
CAS 443878-33-9C12H12N2O3S
Methyl 4-{[(2E)-3-ethyl-4-oxo-1,3-thiazolidin-2-ylidene]amino}benzoate chemical structure, C13H14N2O3S, CAS 591210-89-8
Methyl 4-{[(2E)-3-ethyl-4-oxo-1,3-thiazolidin-2-ylidene]amino}benzoate
CAS 591210-89-8C13H14N2O3S
(2-[(4-Methoxyphenyl)imino]-3-methyl-4-oxo-1,3-thiazolidin-5-yl)acetic acid chemical structure, C13H14N2O4S, CAS 444544-43-8
(2-[(4-Methoxyphenyl)imino]-3-methyl-4-oxo-1,3-thiazolidin-5-yl)acetic acid
CAS 444544-43-8C13H14N2O4S
(Z)-5-Ethyl-3-(pentylsulfonyl)-2-(phenylimino)thiazolidin-4-one chemical structure, C16H22N2O3S2, CAS 468079-54-1
(Z)-5-Ethyl-3-(pentylsulfonyl)-2-(phenylimino)thiazolidin-4-one
CAS 468079-54-1C16H22N2O3S2
3-Methyl-2-[(Z)-3-methylsulfanyl-phenylimino]-thiazolidin-4-one chemical structure, C11H12N2OS2, CAS 591761-91-0
3-Methyl-2-[(Z)-3-methylsulfanyl-phenylimino]-thiazolidin-4-one
CAS 591761-91-0C11H12N2OS2
2-[[2-[2-(4-Chlorophenyl)imino-4-oxo-3-prop-2-enyl-1,3-thiazolidin-5-yl]acetyl]amino]acetic acid chemical structure, C16H16ClN3O4S, CAS 622353-88-2
2-[[2-[2-(4-Chlorophenyl)imino-4-oxo-3-prop-2-enyl-1,3-thiazolidin-5-yl]acetyl]amino]acetic acid
CAS 622353-88-2C16H16ClN3O4S
(E)-4-((3-Allyl-5-(carboxymethyl)-4-oxothiazolidin-2-ylidene)amino)benzoic acid chemical structure, C15H14N2O5S, CAS 380318-18-3
(E)-4-((3-Allyl-5-(carboxymethyl)-4-oxothiazolidin-2-ylidene)amino)benzoic acid
CAS 380318-18-3C15H14N2O5S
(E)-2-(3-Allyl-2-((3-nitrophenyl)imino)-4-oxothiazolidin-5-yl)acetic acid chemical structure, C14H13N3O5S, CAS 380317-74-8
(E)-2-(3-Allyl-2-((3-nitrophenyl)imino)-4-oxothiazolidin-5-yl)acetic acid
CAS 380317-74-8C14H13N3O5S
2-[2-(4-Acetylphenyl)imino-4-oxo-3-prop-2-enyl-1,3-thiazolidin-5-yl]acetic acid chemical structure, C16H16N2O4S, CAS 611192-30-4
2-[2-(4-Acetylphenyl)imino-4-oxo-3-prop-2-enyl-1,3-thiazolidin-5-yl]acetic acid
CAS 611192-30-4C16H16N2O4S
3-Methyl-2-(4-nitro-phenylimino)-thiazolidin-4-one chemical structure, C10H9N3O3S, CAS 63500-84-5
3-Methyl-2-(4-nitro-phenylimino)-thiazolidin-4-one
CAS 63500-84-5C10H9N3O3S
(3-Ethyl-4-oxo-2-phenylimino-thiazolidin-5-yl)-acetic acid chemical structure, C13H14N2O3S, CAS 104445-59-2
(3-Ethyl-4-oxo-2-phenylimino-thiazolidin-5-yl)-acetic acid
CAS 104445-59-2C13H14N2O3S
2-(2-((4-Fluorophenyl)imino)-3-methyl-4-oxothiazolidin-5-yl)acetic acid chemical structure, C12H11FN2O3S, CAS 726169-25-1
2-(2-((4-Fluorophenyl)imino)-3-methyl-4-oxothiazolidin-5-yl)acetic acid
CAS 726169-25-1C12H11FN2O3S
4-[3-Ethyl-4-oxo-thiazolidin-(2Z)-ylideneamino]-benzoic acid ethyl ester chemical structure, C14H16N2O3S, CAS 1147359-42-9
4-[3-Ethyl-4-oxo-thiazolidin-(2Z)-ylideneamino]-benzoic acid ethyl ester
CAS 1147359-42-9C14H16N2O3S