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Murcko scaffold

Ring system with 2 rings and 13 atoms

12 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
12
With full pages
3
Scaffold SMILES

O=C(Nc1cccs1)C1CCCO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cccs1)C1CCCO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

Diethyl 3-methyl-5-[(tetrahydrofuran-2-ylcarbonyl)amino]thiophene-2,4-dicarboxylate chemical structure, C16H21NO6S, CAS 315684-64-1
Diethyl 3-methyl-5-[(tetrahydrofuran-2-ylcarbonyl)amino]thiophene-2,4-dicarboxylate
CAS 315684-64-1C16H21NO6S
Diisopropyl 3-methyl-5-[(tetrahydro-2-furanylcarbonyl)amino]-2,4-thiophenedicarboxylate chemical structure, C18H25NO6S, CAS 329722-90-9
Diisopropyl 3-methyl-5-[(tetrahydro-2-furanylcarbonyl)amino]-2,4-thiophenedicarboxylate
CAS 329722-90-9C18H25NO6S
Ethyl 5-acetyl-4-methyl-2-(oxolane-2-carbonylamino)thiophene-3-carboxylate chemical structure, C15H19NO5S, CAS 544424-94-4
Ethyl 5-acetyl-4-methyl-2-(oxolane-2-carbonylamino)thiophene-3-carboxylate
CAS 544424-94-4C15H19NO5S
N-(3-Cyano-4,5-dimethyl-2-thienyl)tetrahydro-2-furancarboxamide chemical structure, C12H14N2O2S, CAS 354995-30-5
N-(3-Cyano-4,5-dimethyl-2-thienyl)tetrahydro-2-furancarboxamide
CAS 354995-30-5C12H14N2O2S
Propan-2-yl 5-carbamoyl-4-methyl-2-[(tetrahydrofuran-2-ylcarbonyl)amino]thiophene-3-carboxylate chemical structure, C15H20N2O5S, CAS 496016-77-4
Propan-2-yl 5-carbamoyl-4-methyl-2-[(tetrahydrofuran-2-ylcarbonyl)amino]thiophene-3-carboxylate
CAS 496016-77-4C15H20N2O5S
N-[3-(Aminocarbonyl)-4,5-dimethyl-2-thienyl]tetrahydro-2-furancarboxamide chemical structure, C12H16N2O3S, CAS 329222-47-1
N-[3-(Aminocarbonyl)-4,5-dimethyl-2-thienyl]tetrahydro-2-furancarboxamide
CAS 329222-47-1C12H16N2O3S
Propan-2-yl 5-(diethylcarbamoyl)-4-methyl-2-(oxolane-2-carbonylamino)thiophene-3-carboxylate chemical structure, C19H28N2O5S, CAS 551909-70-7
Propan-2-yl 5-(diethylcarbamoyl)-4-methyl-2-(oxolane-2-carbonylamino)thiophene-3-carboxylate
CAS 551909-70-7C19H28N2O5S
N-(3-Carbamoyl-4-ethyl-5-methylthiophen-2-yl)oxolane-2-carboxamide chemical structure, C13H18N2O3S, CAS 424812-53-3
N-(3-Carbamoyl-4-ethyl-5-methylthiophen-2-yl)oxolane-2-carboxamide
CAS 424812-53-3C13H18N2O3S
Ethyl 5-(diethylcarbamoyl)-4-methyl-2-(oxolane-2-carbonylamino)thiophene-3-carboxylate chemical structure, C18H26N2O5S, CAS 438615-33-9
Ethyl 5-(diethylcarbamoyl)-4-methyl-2-(oxolane-2-carbonylamino)thiophene-3-carboxylate
CAS 438615-33-9C18H26N2O5S
Methyl 5-(diethylcarbamoyl)-4-methyl-2-(oxolane-2-carbonylamino)thiophene-3-carboxylate chemical structure, C17H24N2O5S, CAS 543705-41-5
Methyl 5-(diethylcarbamoyl)-4-methyl-2-(oxolane-2-carbonylamino)thiophene-3-carboxylate
CAS 543705-41-5C17H24N2O5S
Ethyl 4-carbamoyl-3-methyl-5-[(tetrahydrofuran-2-ylcarbonyl)amino]thiophene-2-carboxylate chemical structure, C14H18N2O5S, CAS 438617-31-3
Ethyl 4-carbamoyl-3-methyl-5-[(tetrahydrofuran-2-ylcarbonyl)amino]thiophene-2-carboxylate
CAS 438617-31-3C14H18N2O5S
5-Methyl-2-(oxolane-2-amido)thiophene-3-carboxylic acid chemical structure, C11H13NO4S, CAS 1082185-32-7
5-Methyl-2-(oxolane-2-amido)thiophene-3-carboxylic acid
CAS 1082185-32-7C11H13NO4S