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Murcko scaffold

N-(1,3-Thiazol-2-yl)thiophene-2-carboxamide scaffold

49 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
49
With full pages
15
Scaffold SMILES

O=C(Nc1nccs1)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(1,3-Thiazol-2-yl)thiophene-2-carboxamide page
Murcko scaffold O=C(Nc1nccs1)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 49 chemicals

2-(alpha-Thenoylamino)-2-nitro-5-thiazole chemical structure, C8H5N3O3S2, CAS 3810-35-3
2-(alpha-Thenoylamino)-2-nitro-5-thiazole
CAS 3810-35-3C8H5N3O3S2
5-Chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide chemical structure, C8H4ClN3O3S2, CAS 78682-88-9
5-Chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide
CAS 78682-88-9C8H4ClN3O3S2
N-(1,3-Thiazol-2-yl)thiophene-2-carboxamide chemical structure, C8H6N2OS2, CAS 300716-56-7
N-(1,3-Thiazol-2-yl)thiophene-2-carboxamide
CAS 300716-56-7C8H6N2OS2
{2-[(2-Thienylcarbonyl)amino]-1,3-thiazol-4-yl}acetic acid chemical structure, C10H8N2O3S2, CAS 329695-38-7
{2-[(2-Thienylcarbonyl)amino]-1,3-thiazol-4-yl}acetic acid
CAS 329695-38-7C10H8N2O3S2
Ethyl 4-methyl-2-[(2-thienylcarbonyl)amino]-1,3-thiazole-5-carboxylate chemical structure, C12H12N2O3S2, CAS 330978-57-9
Ethyl 4-methyl-2-[(2-thienylcarbonyl)amino]-1,3-thiazole-5-carboxylate
CAS 330978-57-9C12H12N2O3S2
Methyl 4-methyl-2-[(thiophen-2-ylcarbonyl)amino]-1,3-thiazole-5-carboxylate chemical structure, C11H10N2O3S2, CAS 421580-85-0
Methyl 4-methyl-2-[(thiophen-2-ylcarbonyl)amino]-1,3-thiazole-5-carboxylate
CAS 421580-85-0C11H10N2O3S2
Ethyl 2-[2-(thiophene-2-amido)-1,3-thiazol-4-yl]acetate chemical structure, C12H12N2O3S2, CAS 313526-99-7
Ethyl 2-[2-(thiophene-2-amido)-1,3-thiazol-4-yl]acetate
CAS 313526-99-7C12H12N2O3S2
Ethyl 2-(thiophene-2-carbonylamino)-1,3-thiazole-4-carboxylate chemical structure, C11H10N2O3S2, CAS 258338-60-2
Ethyl 2-(thiophene-2-carbonylamino)-1,3-thiazole-4-carboxylate
CAS 258338-60-2C11H10N2O3S2
5-Nitro-N-(1,3-thiazol-2-yl)thiophene-2-carboxamide chemical structure, C8H5N3O3S2, CAS 307510-61-8
5-Nitro-N-(1,3-thiazol-2-yl)thiophene-2-carboxamide
CAS 307510-61-8C8H5N3O3S2
N-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)thiophene-2-carboxamide chemical structure, C11H10N2O2S2, CAS 438619-26-2
N-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)thiophene-2-carboxamide
CAS 438619-26-2C11H10N2O2S2
N-(4-Methyl-1,3-thiazol-2-yl)-2-thiophenecarboxamide chemical structure, C9H8N2OS2, CAS 333426-05-4
N-(4-Methyl-1,3-thiazol-2-yl)-2-thiophenecarboxamide
CAS 333426-05-4C9H8N2OS2
Ethyl (2-{[(5-chlorothiophen-2-yl)carbonyl]amino}-4-methyl-1,3-thiazol-5-yl)acetate chemical structure, C13H13ClN2O3S2, CAS 524927-93-3
Ethyl (2-{[(5-chlorothiophen-2-yl)carbonyl]amino}-4-methyl-1,3-thiazol-5-yl)acetate
CAS 524927-93-3C13H13ClN2O3S2
N-(4,5-Dimethyl-1,3-thiazol-2-yl)-5-methylthiophene-2-carboxamide chemical structure, C11H12N2OS2, CAS 445023-36-9
N-(4,5-Dimethyl-1,3-thiazol-2-yl)-5-methylthiophene-2-carboxamide
CAS 445023-36-9C11H12N2OS2
5-Ethyl-N-(4-methyl-1,3-thiazol-2-yl)thiophene-2-carboxamide chemical structure, C11H12N2OS2, CAS 774588-42-0
5-Ethyl-N-(4-methyl-1,3-thiazol-2-yl)thiophene-2-carboxamide
CAS 774588-42-0C11H12N2OS2
N-(4-tert-Butyl-1,3-thiazol-2-yl)-5-chlorothiophene-2-carboxamide chemical structure, C12H13ClN2OS2, CAS 325730-29-8
N-(4-tert-Butyl-1,3-thiazol-2-yl)-5-chlorothiophene-2-carboxamide
CAS 325730-29-8C12H13ClN2OS2
Ethyl (2-{[(5-bromo-2-thienyl)carbonyl]amino}-1,3-thiazol-4-yl)acetate chemical structure, C12H11BrN2O3S2, CAS 391223-59-9
Ethyl (2-{[(5-bromo-2-thienyl)carbonyl]amino}-1,3-thiazol-4-yl)acetate
CAS 391223-59-9C12H11BrN2O3S2
5-Bromo-N-(1,3-thiazol-2-yl)thiophene-2-carboxamide chemical structure, C8H5BrN2OS2, CAS 313404-40-9
5-Bromo-N-(1,3-thiazol-2-yl)thiophene-2-carboxamide
CAS 313404-40-9C8H5BrN2OS2
N-(4-tert-Butyl-1,3-thiazol-2-yl)-5-nitrothiophene-2-carboxamide chemical structure, C12H13N3O3S2, CAS 325988-15-6
N-(4-tert-Butyl-1,3-thiazol-2-yl)-5-nitrothiophene-2-carboxamide
CAS 325988-15-6C12H13N3O3S2
5-Ethyl-4-methyl-N-(4-methyl-1,3-thiazol-2-yl)thiophene-2-carboxamide chemical structure, C12H14N2OS2, CAS 796115-54-3
5-Ethyl-4-methyl-N-(4-methyl-1,3-thiazol-2-yl)thiophene-2-carboxamide
CAS 796115-54-3C12H14N2OS2
N-(4-tert-Butyl-2-thiazolyl)-5-methyl-2-thiophenecarboxamide chemical structure, C13H16N2OS2, CAS 795295-49-7
N-(4-tert-Butyl-2-thiazolyl)-5-methyl-2-thiophenecarboxamide
CAS 795295-49-7C13H16N2OS2
5-Ethyl-4-methyl-N-(1,3-thiazol-2-yl)thiophene-2-carboxamide chemical structure, C11H12N2OS2, CAS 851209-64-8
5-Ethyl-4-methyl-N-(1,3-thiazol-2-yl)thiophene-2-carboxamide
CAS 851209-64-8C11H12N2OS2
5-Methyl-N-(1,3-thiazol-2-yl)thiophene-2-carboxamide chemical structure, C9H8N2OS2, CAS 790725-27-8
5-Methyl-N-(1,3-thiazol-2-yl)thiophene-2-carboxamide
CAS 790725-27-8C9H8N2OS2
Ethyl 4-methyl-2-(5-nitrothiophene-2-carboxamido)thiazole-5-carboxylate chemical structure, C12H11N3O5S2, CAS 5973-77-3
Ethyl 4-methyl-2-(5-nitrothiophene-2-carboxamido)thiazole-5-carboxylate
CAS 5973-77-3C12H11N3O5S2
Prop-2-enyl 4-methyl-2-(2-thienylcarbonylamino)-1,3-thiazole-5-carboxylate chemical structure, C13H12N2O3S2, CAS 431892-97-6
Prop-2-enyl 4-methyl-2-(2-thienylcarbonylamino)-1,3-thiazole-5-carboxylate
CAS 431892-97-6C13H12N2O3S2