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Murcko scaffold

Ring system with 2 rings and 13 atoms

56 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
56
With full pages
9
Scaffold SMILES

O=C(Nc1nccs1)c1ccn[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1nccs1)c1ccn[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 56 chemicals

1-Ethyl-N-(thiazol-2-yl)-1H-pyrazole-5-carboxamide chemical structure, C9H10N4OS, CAS 492426-57-0
1-Ethyl-N-(thiazol-2-yl)-1H-pyrazole-5-carboxamide
CAS 492426-57-0C9H10N4OS
4-Bromo-1-ethyl-N-(1,3-thiazol-2-yl)-1H-pyrazole-3-carboxamide chemical structure, C9H9BrN4OS, CAS 514801-29-7
4-Bromo-1-ethyl-N-(1,3-thiazol-2-yl)-1H-pyrazole-3-carboxamide
CAS 514801-29-7C9H9BrN4OS
1,5-Dimethyl-N-(4-methyl-1,3-thiazol-2-yl)-4-nitropyrazole-3-carboxamide chemical structure, C10H11N5O3S, CAS 515832-00-5
1,5-Dimethyl-N-(4-methyl-1,3-thiazol-2-yl)-4-nitropyrazole-3-carboxamide
CAS 515832-00-5C10H11N5O3S
4-Chloro-1,5-dimethyl-N-(4-methyl-1,3-thiazol-2-yl)pyrazole-3-carboxamide chemical structure, C10H11ClN4OS, CAS 515829-87-5
4-Chloro-1,5-dimethyl-N-(4-methyl-1,3-thiazol-2-yl)pyrazole-3-carboxamide
CAS 515829-87-5C10H11ClN4OS
1-Ethyl-N-(thiazol-2-yl)-1H-pyrazole-3-carboxamide chemical structure, C9H10N4OS, CAS 514801-40-2
1-Ethyl-N-(thiazol-2-yl)-1H-pyrazole-3-carboxamide
CAS 514801-40-2C9H10N4OS
4-Bromo-2-ethyl-N-(1,3-thiazol-2-yl)pyrazole-3-carboxamide chemical structure, C9H9BrN4OS, CAS 492426-56-9
4-Bromo-2-ethyl-N-(1,3-thiazol-2-yl)pyrazole-3-carboxamide
CAS 492426-56-9C9H9BrN4OS
2-Methyl-N-(1,3-thiazol-2-yl)pyrazole-3-carboxamide chemical structure, C8H8N4OS, CAS 489406-52-2
2-Methyl-N-(1,3-thiazol-2-yl)pyrazole-3-carboxamide
CAS 489406-52-2C8H8N4OS
4-Iodo-1-methyl-N-(1,3-thiazol-2-yl)-1H-pyrazole-5-carboxamide chemical structure, C8H7IN4OS, CAS 512827-66-6
4-Iodo-1-methyl-N-(1,3-thiazol-2-yl)-1H-pyrazole-5-carboxamide
CAS 512827-66-6C8H7IN4OS
4-Bromo-1-methyl-N-(1,3-thiazol-2-yl)-1H-pyrazole-3-carboxamide chemical structure, C8H7BrN4OS, CAS 489407-23-0
4-Bromo-1-methyl-N-(1,3-thiazol-2-yl)-1H-pyrazole-3-carboxamide
CAS 489407-23-0C8H7BrN4OS
4-Bromo-N-(5-bromo-1,3-thiazol-2-yl)-1-methyl-1H-pyrazole-3-carboxamide chemical structure, C8H6Br2N4OS, CAS 515176-23-5
4-Bromo-N-(5-bromo-1,3-thiazol-2-yl)-1-methyl-1H-pyrazole-3-carboxamide
CAS 515176-23-5C8H6Br2N4OS
1-Methyl-4-nitro-N-(thiazol-2-yl)-1H-pyrazole-3-carboxamide chemical structure, C8H7N5O3S, CAS 512827-24-6
1-Methyl-4-nitro-N-(thiazol-2-yl)-1H-pyrazole-3-carboxamide
CAS 512827-24-6C8H7N5O3S
1-Methyl-4-nitro-N-(thiazol-2-yl)-1H-pyrazole-5-carboxamide chemical structure, C8H7N5O3S, CAS 512827-63-3
1-Methyl-4-nitro-N-(thiazol-2-yl)-1H-pyrazole-5-carboxamide
CAS 512827-63-3C8H7N5O3S
4-Chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)-1-ethyl-1H-pyrazole-5-carboxamide chemical structure, C11H13ClN4OS, CAS 515150-80-8
4-Chloro-N-(4,5-dimethyl-1,3-thiazol-2-yl)-1-ethyl-1H-pyrazole-5-carboxamide
CAS 515150-80-8C11H13ClN4OS
N-(5-Bromo-1,3-thiazol-2-yl)-1-methyl-1H-pyrazole-5-carboxamide chemical structure, C8H7BrN4OS, CAS 1005645-11-3
N-(5-Bromo-1,3-thiazol-2-yl)-1-methyl-1H-pyrazole-5-carboxamide
CAS 1005645-11-3C8H7BrN4OS
4-Iodo-1-methyl-N-(1,3-thiazol-2-yl)pyrazole-3-carboxamide chemical structure, C8H7IN4OS, CAS 489406-47-5
4-Iodo-1-methyl-N-(1,3-thiazol-2-yl)pyrazole-3-carboxamide
CAS 489406-47-5C8H7IN4OS
N-(5-Bromo-1,3-thiazol-2-yl)-1-methyl-4-nitropyrazole-3-carboxamide chemical structure, C8H6BrN5O3S, CAS 957490-13-0
N-(5-Bromo-1,3-thiazol-2-yl)-1-methyl-4-nitropyrazole-3-carboxamide
CAS 957490-13-0C8H6BrN5O3S
1,3-Dimethyl-N-(4-methyl-1,3-thiazol-2-yl)-4-nitro-1H-pyrazole-5-carboxamide chemical structure, C10H11N5O3S, CAS 514839-42-0
1,3-Dimethyl-N-(4-methyl-1,3-thiazol-2-yl)-4-nitro-1H-pyrazole-5-carboxamide
CAS 514839-42-0C10H11N5O3S
1-Ethyl-N-(5-methylthiazol-2-yl)-1H-pyrazole-3-carboxamide chemical structure, C10H12N4OS, CAS 955567-17-6
1-Ethyl-N-(5-methylthiazol-2-yl)-1H-pyrazole-3-carboxamide
CAS 955567-17-6C10H12N4OS
1-Methyl-N-(5-methyl-2-thiazolyl)-1H-pyrazole-5-carboxamide chemical structure, C9H10N4OS, CAS 955552-19-9
1-Methyl-N-(5-methyl-2-thiazolyl)-1H-pyrazole-5-carboxamide
CAS 955552-19-9C9H10N4OS
Ethyl 2-(1,5-dimethyl-1H-pyrazole-3-carboxamido)-4-methylthiazole-5-carboxylate chemical structure, C13H16N4O3S, CAS 1013772-62-7
Ethyl 2-(1,5-dimethyl-1H-pyrazole-3-carboxamido)-4-methylthiazole-5-carboxylate
CAS 1013772-62-7C13H16N4O3S
N-(5-Acetyl-4-methylthiazol-2-yl)-1,5-dimethyl-1H-pyrazole-3-carboxamide chemical structure, C12H14N4O2S, CAS 1013782-53-0
N-(5-Acetyl-4-methylthiazol-2-yl)-1,5-dimethyl-1H-pyrazole-3-carboxamide
CAS 1013782-53-0C12H14N4O2S
Ethyl 2-(1,5-dimethyl-1H-pyrazole-3-carboxamido)thiazole-4-carboxylate chemical structure, C12H14N4O3S, CAS 1013782-83-6
Ethyl 2-(1,5-dimethyl-1H-pyrazole-3-carboxamido)thiazole-4-carboxylate
CAS 1013782-83-6C12H14N4O3S
1,5-Dimethyl-N-(thiazol-2-yl)-1H-pyrazole-3-carboxamide chemical structure, C9H10N4OS, CAS 1013782-63-2
1,5-Dimethyl-N-(thiazol-2-yl)-1H-pyrazole-3-carboxamide
CAS 1013782-63-2C9H10N4OS
Ethyl 2-((1,5-dimethyl-1H-pyrazole-3-carbonyl)imino)-3,4-dimethyl-2,3-dihydrothiazole-5-carboxylate chemical structure, C14H18N4O3S, CAS 1173470-12-6
Ethyl 2-((1,5-dimethyl-1H-pyrazole-3-carbonyl)imino)-3,4-dimethyl-2,3-dihydrothiazole-5-carboxylate
CAS 1173470-12-6C14H18N4O3S