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Murcko scaffold

Ring system with 3 rings and 24 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
11
With full pages
6
Scaffold SMILES

O=C(NN=Cc1ccccc1)c1ccc(COc2ccccc2)o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccccc1)c1ccc(COc2ccccc2)o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

5-[(2-Chlorophenoxy)methyl]-N-[(E)-(4-ethoxy-3-methoxyphenyl)methylideneamino]furan-2-carboxamide chemical structure, C22H21ClN2O5, CAS 444925-84-2
5-[(2-Chlorophenoxy)methyl]-N-[(E)-(4-ethoxy-3-methoxyphenyl)methylideneamino]furan-2-carboxamide
CAS 444925-84-2C22H21ClN2O5
Methyl 4-[(E)-[[5-[(2,5-dichlorophenoxy)methyl]furan-2-carbonyl]hydrazinylidene]methyl]benzoate chemical structure, C21H16Cl2N2O5, CAS 444931-36-6
Methyl 4-[(E)-[[5-[(2,5-dichlorophenoxy)methyl]furan-2-carbonyl]hydrazinylidene]methyl]benzoate
CAS 444931-36-6C21H16Cl2N2O5
5-[(2,4-Dichlorophenoxy)methyl]-N'-(3-methoxybenzylidene)-2-furohydrazide chemical structure, C20H16Cl2N2O4, CAS 444933-07-7
5-[(2,4-Dichlorophenoxy)methyl]-N'-(3-methoxybenzylidene)-2-furohydrazide
CAS 444933-07-7C20H16Cl2N2O4
5-[(4-tert-Butylphenoxy)methyl]-N'-{4-nitrobenzylidene}-2-furohydrazide chemical structure, C23H23N3O5, CAS 514220-49-6
5-[(4-tert-Butylphenoxy)methyl]-N'-{4-nitrobenzylidene}-2-furohydrazide
CAS 514220-49-6C23H23N3O5
N'-{3-Nitrobenzylidene}-5-[(2-methoxy-4-propylphenoxy)methyl]-2-furohydrazide chemical structure, C23H23N3O6, CAS 514220-50-9
N'-{3-Nitrobenzylidene}-5-[(2-methoxy-4-propylphenoxy)methyl]-2-furohydrazide
CAS 514220-50-9C23H23N3O6
5-[(2-Chlorophenoxy)methyl]-N'-(2-fluorobenzylidene)-2-furohydrazide chemical structure, C19H14ClFN2O3, CAS 444998-78-1
5-[(2-Chlorophenoxy)methyl]-N'-(2-fluorobenzylidene)-2-furohydrazide
CAS 444998-78-1C19H14ClFN2O3
5-[(2-Chlorophenoxy)methyl]-N'-(2,4-dimethoxy-3-methylbenzylidene)-2-furohydrazide chemical structure, C22H21ClN2O5, CAS 445000-86-2
5-[(2-Chlorophenoxy)methyl]-N'-(2,4-dimethoxy-3-methylbenzylidene)-2-furohydrazide
CAS 445000-86-2C22H21ClN2O5
5-[(4-Propylphenoxy)methyl]-N-[(E)-(2,3,4-trimethoxyphenyl)methylideneamino]furan-2-carboxamide chemical structure, C25H28N2O6, CAS 445021-94-3
5-[(4-Propylphenoxy)methyl]-N-[(E)-(2,3,4-trimethoxyphenyl)methylideneamino]furan-2-carboxamide
CAS 445021-94-3C25H28N2O6
N-[4-(N-{5-[(2-Chlorophenoxy)methyl]-2-furoyl}ethanehydrazonoyl)phenyl]acetamide chemical structure, C22H20ClN3O4, CAS 445013-04-7
N-[4-(N-{5-[(2-Chlorophenoxy)methyl]-2-furoyl}ethanehydrazonoyl)phenyl]acetamide
CAS 445013-04-7C22H20ClN3O4
N'-{4-Nitrobenzylidene}-5-({2-nitro-4-methylphenoxy}methyl)-2-furohydrazide chemical structure, C20H16N4O7, CAS 445001-27-4
N'-{4-Nitrobenzylidene}-5-({2-nitro-4-methylphenoxy}methyl)-2-furohydrazide
CAS 445001-27-4C20H16N4O7
N'-(3-Bromo-4-hydroxy-5-methoxybenzylidene)-5-[(2-chlorophenoxy)methyl]-2-furohydrazide chemical structure, C20H16BrClN2O5, CAS 445007-42-1
N'-(3-Bromo-4-hydroxy-5-methoxybenzylidene)-5-[(2-chlorophenoxy)methyl]-2-furohydrazide
CAS 445007-42-1C20H16BrClN2O5