CompoundList
Sign in
Murcko scaffold

1,2-Diphenyl-1H-imidazole scaffold

53 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
53
With full pages
8
Scaffold SMILES

c1ccc(-c2nccn2-c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,2-Diphenyl-1H-imidazole page
Murcko scaffold c1ccc(-c2nccn2-c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 53 chemicals

4-[2-(4-Chlorophenyl)-4,5-dimethyl-1H-imidazol-1-yl]aniline chemical structure, C17H16ClN3, CAS 754996-28-6
4-[2-(4-Chlorophenyl)-4,5-dimethyl-1H-imidazol-1-yl]aniline
CAS 754996-28-6C17H16ClN3
5-(Chloromethyl)-1-(4-fluorophenyl)-4-isopropyl-2-phenyl-1H-imidazole chemical structure, C19H18ClFN2, CAS 196875-70-4
5-(Chloromethyl)-1-(4-fluorophenyl)-4-isopropyl-2-phenyl-1H-imidazole
CAS 196875-70-4C19H18ClFN2
1-(4-Fluorophenyl)-5-(hydroxymethyl)-4-isopropyl-2-phenylimidazole chemical structure, C19H19FN2O, CAS 109083-74-1
1-(4-Fluorophenyl)-5-(hydroxymethyl)-4-isopropyl-2-phenylimidazole
CAS 109083-74-1C19H19FN2O
1-(4-Fluorophenyl)-4-isopropyl-2-phenylimidazole-5-carboxaldehyde chemical structure, C19H17FN2O, CAS 109083-75-2
1-(4-Fluorophenyl)-4-isopropyl-2-phenylimidazole-5-carboxaldehyde
CAS 109083-75-2C19H17FN2O
Ethyl (E)-7-[3-(4-fluorophenyl)-2-phenyl-5-propan-2-ylimidazol-4-yl]-3,5-dihydroxyhept-6-enoate chemical structure, C27H31FN2O4, CAS 109083-30-9
Ethyl (E)-7-[3-(4-fluorophenyl)-2-phenyl-5-propan-2-ylimidazol-4-yl]-3,5-dihydroxyhept-6-enoate
CAS 109083-30-9C27H31FN2O4
Ethyl 3-(1-(4-fluorophenyl)-4-isopropyl-2-phenylimidazol-5-yl)acrylate chemical structure, C23H23FN2O2, CAS 109083-76-3
Ethyl 3-(1-(4-fluorophenyl)-4-isopropyl-2-phenylimidazol-5-yl)acrylate
CAS 109083-76-3C23H23FN2O2
2-(4-Chlorophenyl)-4-methyl-1-(4-(methylsulfonyl)phenyl)-1H-imidazole chemical structure, C17H15ClN2O2S, CAS 177660-54-7
2-(4-Chlorophenyl)-4-methyl-1-(4-(methylsulfonyl)phenyl)-1H-imidazole
CAS 177660-54-7C17H15ClN2O2S
1H-Imidazole,2-(3-fluoro-4-methoxyphenyl)-1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)- chemical structure, C18H14F4N2O3S, CAS 177660-67-2
1H-Imidazole,2-(3-fluoro-4-methoxyphenyl)-1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)-
CAS 177660-67-2C18H14F4N2O3S
2-(2-Phenyl-1H-imidazol-1-yl)aniline chemical structure, C15H13N3, CAS 168210-42-2
2-(2-Phenyl-1H-imidazol-1-yl)aniline
CAS 168210-42-2C15H13N3
1H-Imidazole,2-(3-chloro-4-methylphenyl)-1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)- chemical structure, C18H14ClF3N2O2S, CAS 177660-65-0
1H-Imidazole,2-(3-chloro-4-methylphenyl)-1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)-
CAS 177660-65-0C18H14ClF3N2O2S
4-Methyl-1-(4-methylphenyl)-2-phenyl-1H-imidazole chemical structure, C17H16N2, CAS 1025870-44-3
4-Methyl-1-(4-methylphenyl)-2-phenyl-1H-imidazole
CAS 1025870-44-3C17H16N2
Ethyl 2-(2,4-dichlorophenyl)-1-(4-methoxyphenyl)-5-methyl-1H-imidazole-4-carboxylate chemical structure, C20H18Cl2N2O3, CAS 505073-86-9
Ethyl 2-(2,4-dichlorophenyl)-1-(4-methoxyphenyl)-5-methyl-1H-imidazole-4-carboxylate
CAS 505073-86-9C20H18Cl2N2O3
1-(3,4,5-Trimethoxyphenyl)-2-(4-methoxyphenyl)-1H-imidazole chemical structure, C19H20N2O4, CAS 882971-07-5
1-(3,4,5-Trimethoxyphenyl)-2-(4-methoxyphenyl)-1H-imidazole
CAS 882971-07-5C19H20N2O4
1,2-Bis(4-methoxyphenyl)-1H-imidazole chemical structure, C17H16N2O2, CAS 852525-37-2
1,2-Bis(4-methoxyphenyl)-1H-imidazole
CAS 852525-37-2C17H16N2O2
Ethyl 2-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-4-imidazolecarboxylate chemical structure, C18H13BrCl2N2O2, CAS 850339-33-2
Ethyl 2-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-4-imidazolecarboxylate
CAS 850339-33-2C18H13BrCl2N2O2
1-(2-Methylphenyl)-2-phenylimidazole chemical structure, C16H14N2, CAS 870450-94-5
1-(2-Methylphenyl)-2-phenylimidazole
CAS 870450-94-5C16H14N2
1-(4-Methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)-1H-imidazole chemical structure, C19H20N2O4, CAS 882971-09-7
1-(4-Methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)-1H-imidazole
CAS 882971-09-7C19H20N2O4
1,2-Diphenyl-1H-imidazole chemical structure, C15H12N2, CAS 52179-66-5
1,2-Diphenyl-1H-imidazole
CAS 52179-66-5C15H12N2
4-(2-Phenyl-1H-imidazol-1-yl)benzonitrile chemical structure, C16H11N3, CAS 167758-59-0
4-(2-Phenyl-1H-imidazol-1-yl)benzonitrile
CAS 167758-59-0C16H11N3
5-Chloro-2-(2-phenyl-1H-imidazol-1-yl)aniline chemical structure, C15H12ClN3, CAS 937606-17-2
5-Chloro-2-(2-phenyl-1H-imidazol-1-yl)aniline
CAS 937606-17-2C15H12ClN3
1-[4-(2-Phenyl-1H-imidazol-1-yl)phenyl]methanamine chemical structure, C16H15N3, CAS 937598-81-7
1-[4-(2-Phenyl-1H-imidazol-1-yl)phenyl]methanamine
CAS 937598-81-7C16H15N3
5-Chloromethyl-1-(4-fluorophenyl)-4-isopropyl-2-phenylimidazole hydrochloride chemical structure, C19H19Cl2FN2, CAS 123630-29-5
5-Chloromethyl-1-(4-fluorophenyl)-4-isopropyl-2-phenylimidazole hydrochloride
CAS 123630-29-5C19H19Cl2FN2
2-(2,4-Difluorophenyl)-1-(3-ethoxyphenyl)-1H-imidazole-4-carboxylic acid chemical structure, C18H14F2N2O3, CAS 954382-68-4
2-(2,4-Difluorophenyl)-1-(3-ethoxyphenyl)-1H-imidazole-4-carboxylic acid
CAS 954382-68-4C18H14F2N2O3
2-(2,4-Difluorophenyl)-1-phenyl-1H-imidazole chemical structure, C15H10F2N2, CAS 872327-73-6
2-(2,4-Difluorophenyl)-1-phenyl-1H-imidazole
CAS 872327-73-6C15H10F2N2