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Murcko scaffold

Ring system with 2 rings and 15 atoms

11 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
11
With full pages
1
Scaffold SMILES

c1ccc(O[SiH2]Oc2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(O[SiH2]Oc2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

Silane, dimethyldiphenoxy- chemical structure, C14H16O2Si, CAS 3440-02-6
Silane, dimethyldiphenoxy-
CAS 3440-02-6C14H16O2Si
Bis(4-chlorophenoxy)(dimethyl)silane chemical structure, C14H14Cl2O2Si, CAS 18414-46-5
Bis(4-chlorophenoxy)(dimethyl)silane
CAS 18414-46-5C14H14Cl2O2Si
Dichlorobis(2,6-di-tert-butyl-4-methylphenoxy)silane chemical structure, C30H46Cl2O2Si, CAS 88330-99-8
Dichlorobis(2,6-di-tert-butyl-4-methylphenoxy)silane
CAS 88330-99-8C30H46Cl2O2Si
Bis(p-aminophenoxy)dimethylsilane chemical structure, C14H18N2O2Si, CAS 1223-16-1
Bis(p-aminophenoxy)dimethylsilane
CAS 1223-16-1C14H18N2O2Si
Dimethylbis(2,4,6-tribromophenoxy)silane chemical structure, C14H10Br6O2Si, CAS 93675-59-3
Dimethylbis(2,4,6-tribromophenoxy)silane
CAS 93675-59-3C14H10Br6O2Si
2,2'-((Methoxymethylsilylene)bis(oxy))bisbenzoic acid chemical structure, C16H16O7Si, CAS 84713-00-8
2,2'-((Methoxymethylsilylene)bis(oxy))bisbenzoic acid
CAS 84713-00-8C16H16O7Si
Bis(4-allyl-2-methoxyphenoxy)methoxymethylsilane chemical structure, C22H28O5Si, CAS 83817-75-8
Bis(4-allyl-2-methoxyphenoxy)methoxymethylsilane
CAS 83817-75-8C22H28O5Si
Ethenyl(methyl)diphenoxysilane chemical structure, C15H16O2Si, CAS 62883-97-0
Ethenyl(methyl)diphenoxysilane
CAS 62883-97-0C15H16O2Si
Dimethylbis(2,4,6-trimethylphenoxy)silane chemical structure, C20H28O2Si, CAS 183578-18-9
Dimethylbis(2,4,6-trimethylphenoxy)silane
CAS 183578-18-9C20H28O2Si
[(Dimethylsilanediyl)bis(oxy-4,1-phenyleneoxy)]bis[chloro(dimethyl)silane] chemical structure, C18H26Cl2O4Si3, CAS 60744-85-6
[(Dimethylsilanediyl)bis(oxy-4,1-phenyleneoxy)]bis[chloro(dimethyl)silane]
CAS 60744-85-6C18H26Cl2O4Si3
Dimethyl 4,4'-[(dimethylsilanediyl)bis(oxy)]dibenzoate chemical structure, C18H20O6Si, CAS 906-36-5
Dimethyl 4,4'-[(dimethylsilanediyl)bis(oxy)]dibenzoate
CAS 906-36-5C18H20O6Si