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Murcko scaffold

Ring system with 3 rings and 14 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
9
With full pages
3
Scaffold SMILES

c1csc(-c2ccc3ccsc3n2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1csc(-c2ccc3ccsc3n2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

3-Amino-6-(thiophen-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carbonitrile chemical structure, C13H6F3N3S2, CAS 299198-01-9
3-Amino-6-(thiophen-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carbonitrile
CAS 299198-01-9C13H6F3N3S2
1-[3-Amino-6-(2-thienyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl]ethan-1-one chemical structure, C14H9F3N2OS2, CAS 285980-95-2
1-[3-Amino-6-(2-thienyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl]ethan-1-one
CAS 285980-95-2C14H9F3N2OS2
3-Amino-6-(thiophen-2-yl)thieno[2,3-b]pyridine-2-carbonitrile chemical structure, C12H7N3S2, CAS 313380-31-3
3-Amino-6-(thiophen-2-yl)thieno[2,3-b]pyridine-2-carbonitrile
CAS 313380-31-3C12H7N3S2
Methyl 3-amino-6-(thiophen-2-yl)thieno[2,3-b]pyridine-2-carboxylate chemical structure, C13H10N2O2S2, CAS 401937-08-4
Methyl 3-amino-6-(thiophen-2-yl)thieno[2,3-b]pyridine-2-carboxylate
CAS 401937-08-4C13H10N2O2S2
Ethyl 3-amino-6-(thiophen-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxylate chemical structure, C15H11F3N2O2S2, CAS 340816-56-0
Ethyl 3-amino-6-(thiophen-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxylate
CAS 340816-56-0C15H11F3N2O2S2
3-Amino-N-(propan-2-yl)-6-(thiophen-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide chemical structure, C16H14F3N3OS2, CAS 371945-19-6
3-Amino-N-(propan-2-yl)-6-(thiophen-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide
CAS 371945-19-6C16H14F3N3OS2
Ethyl 3-methyl-6-(thiophen-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxylate chemical structure, C16H12F3NO2S2, CAS 379728-92-4
Ethyl 3-methyl-6-(thiophen-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxylate
CAS 379728-92-4C16H12F3NO2S2
3-Methyl-6-(thiophen-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carbohydrazide chemical structure, C14H10F3N3OS2, CAS 885458-77-5
3-Methyl-6-(thiophen-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carbohydrazide
CAS 885458-77-5C14H10F3N3OS2
3-Methyl-6-(thiophen-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxylic acid chemical structure, C14H8F3NO2S2, CAS 721893-48-7
3-Methyl-6-(thiophen-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxylic acid
CAS 721893-48-7C14H8F3NO2S2