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Murcko scaffold

3-(2-Thiazolyl)piperidine scaffold

88 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
88
With full pages
6
Scaffold SMILES

c1csc(C2CCCNC2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-(2-Thiazolyl)piperidine page
Murcko scaffold c1csc(C2CCCNC2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 88 chemicals

3-(2-Thiazolyl)piperidine chemical structure, C8H12N2S, CAS 630121-84-5
3-(2-Thiazolyl)piperidine
CAS 630121-84-5C8H12N2S
3-(4-Methyl-1,3-thiazol-2-yl)piperidine chemical structure, C9H14N2S, CAS 933683-00-2
3-(4-Methyl-1,3-thiazol-2-yl)piperidine
CAS 933683-00-2C9H14N2S
3-(Dimethyl-1,3-thiazol-2-yl)piperidine chemical structure, C10H16N2S, CAS 1017153-30-8
3-(Dimethyl-1,3-thiazol-2-yl)piperidine
CAS 1017153-30-8C10H16N2S
3-(4-Ethyl-1,3-thiazol-2-yl)piperidine chemical structure, C10H16N2S, CAS 1017250-60-0
3-(4-Ethyl-1,3-thiazol-2-yl)piperidine
CAS 1017250-60-0C10H16N2S
3-(4-(Propan-2-yl)-1,3-thiazol-2-yl)piperidine chemical structure, C11H18N2S, CAS 1017184-32-5
3-(4-(Propan-2-yl)-1,3-thiazol-2-yl)piperidine
CAS 1017184-32-5C11H18N2S
3-(1,3-Thiazol-2-yl)piperidine dihydrochloride chemical structure, C8H14Cl2N2S, CAS 1258641-49-4
3-(1,3-Thiazol-2-yl)piperidine dihydrochloride
CAS 1258641-49-4C8H14Cl2N2S
Ethyl 2-(1-(tert-butoxycarbonyl)piperidin-3-yl)thiazole-4-carboxylate chemical structure, C16H24N2O4S, CAS 1192248-02-4
Ethyl 2-(1-(tert-butoxycarbonyl)piperidin-3-yl)thiazole-4-carboxylate
CAS 1192248-02-4C16H24N2O4S
3-(2-Thiazolyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester chemical structure, C13H20N2O2S, CAS 630121-83-4
3-(2-Thiazolyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
CAS 630121-83-4C13H20N2O2S
3-(5-Methyl-1,3-thiazol-2-yl)piperidine chemical structure, C9H14N2S, CAS 1248102-35-3
3-(5-Methyl-1,3-thiazol-2-yl)piperidine
CAS 1248102-35-3C9H14N2S
1-Piperidinecarboxylic acid, 3-[4-(chloromethyl)-2-thiazolyl]-, 1,1-dimethylethyl ester chemical structure, C14H21ClN2O2S, CAS 1044136-63-1
1-Piperidinecarboxylic acid, 3-[4-(chloromethyl)-2-thiazolyl]-, 1,1-dimethylethyl ester
CAS 1044136-63-1C14H21ClN2O2S
2-(1-(tert-Butoxycarbonyl)piperidin-3-yl)thiazole-4-carboxylic acid chemical structure, C14H20N2O4S, CAS 955401-18-0
2-(1-(tert-Butoxycarbonyl)piperidin-3-yl)thiazole-4-carboxylic acid
CAS 955401-18-0C14H20N2O4S
2-(Piperidin-3-yl)-1,3-thiazole-4-carboxylic acid chemical structure, C9H12N2O2S, CAS 1499494-04-0
2-(Piperidin-3-yl)-1,3-thiazole-4-carboxylic acid
CAS 1499494-04-0C9H12N2O2S
3-[4-(Trifluoromethyl)-1,3-thiazol-2-yl]piperidine chemical structure, C9H11F3N2S, CAS 1249566-89-9
3-[4-(Trifluoromethyl)-1,3-thiazol-2-yl]piperidine
CAS 1249566-89-9C9H11F3N2S
2-[2-(Piperidin-3-yl)-1,3-thiazol-4-yl]acetic acid chemical structure, C10H14N2O2S, CAS 1486000-42-3
2-[2-(Piperidin-3-yl)-1,3-thiazol-4-yl]acetic acid
CAS 1486000-42-3C10H14N2O2S
Ethyl 4-methyl-2-(piperidin-3-yl)thiazole-5-carboxylate chemical structure, C12H18N2O2S, CAS 1211525-47-1
Ethyl 4-methyl-2-(piperidin-3-yl)thiazole-5-carboxylate
CAS 1211525-47-1C12H18N2O2S
4-Methyl-2-(piperidin-3-yl)thiazole-5-carboxylic acid chemical structure, C10H14N2O2S, CAS 1491498-19-1
4-Methyl-2-(piperidin-3-yl)thiazole-5-carboxylic acid
CAS 1491498-19-1C10H14N2O2S
Methyl 2-(piperidin-3-yl)-1,3-thiazole-4-carboxylate chemical structure, C10H14N2O2S, CAS 1488869-68-6
Methyl 2-(piperidin-3-yl)-1,3-thiazole-4-carboxylate
CAS 1488869-68-6C10H14N2O2S
Ethyl 2-(piperidin-3-yl)-1,3-thiazole-4-carboxylate chemical structure, C11H16N2O2S, CAS 1192274-83-1
Ethyl 2-(piperidin-3-yl)-1,3-thiazole-4-carboxylate
CAS 1192274-83-1C11H16N2O2S
5-Bromo-2-(piperidin-3-yl)thiazole chemical structure, C8H11BrN2S, CAS 1521684-25-2
5-Bromo-2-(piperidin-3-yl)thiazole
CAS 1521684-25-2C8H11BrN2S
3-(5-Bromo-4-methyl-thiazol-2-yl)-1-isopropyl-piperidine chemical structure, C12H19BrN2S, CAS 1361113-61-2
3-(5-Bromo-4-methyl-thiazol-2-yl)-1-isopropyl-piperidine
CAS 1361113-61-2C12H19BrN2S
1-(3-(5-Bromo-4-methylthiazol-2-yl)piperidin-1-yl)ethanone chemical structure, C11H15BrN2OS, CAS 1361116-89-3
1-(3-(5-Bromo-4-methylthiazol-2-yl)piperidin-1-yl)ethanone
CAS 1361116-89-3C11H15BrN2OS
3-(5-Bromo-4-methyl-thiazol-2-yl)-1-methanesulfonyl-piperidine chemical structure, C10H15BrN2O2S2, CAS 1361116-80-4
3-(5-Bromo-4-methyl-thiazol-2-yl)-1-methanesulfonyl-piperidine
CAS 1361116-80-4C10H15BrN2O2S2
1-[3-(5-Bromo-1,3-thiazol-2-yl)piperidin-1-yl]ethanone chemical structure, C10H13BrN2OS, CAS 1316218-61-7
1-[3-(5-Bromo-1,3-thiazol-2-yl)piperidin-1-yl]ethanone
CAS 1316218-61-7C10H13BrN2OS
5-Bromo-2-(1-(methylsulfonyl)piperidin-3-yl)thiazole chemical structure, C9H13BrN2O2S2, CAS 1316226-01-3
5-Bromo-2-(1-(methylsulfonyl)piperidin-3-yl)thiazole
CAS 1316226-01-3C9H13BrN2O2S2