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Murcko scaffold

Ring system with 4 rings and 21 atoms

30 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
30
With full pages
1
Scaffold SMILES

c1ccc(-c2cnc3[nH]cc(-c4ccccc4)c3c2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2cnc3[nH]cc(-c4ccccc4)c3c2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

4-{5-Phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl}benzoic acid chemical structure, C20H14N2O2, CAS 890839-40-4
4-{5-Phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl}benzoic acid
CAS 890839-40-4C20H14N2O2
4-[5-[3-(Methylsulfonyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-3-yl]benzenepropanoic acid chemical structure, C23H20N2O4S, CAS 890839-84-6
4-[5-[3-(Methylsulfonyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-3-yl]benzenepropanoic acid
CAS 890839-84-6C23H20N2O4S
4-(5-Phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-phenylamine chemical structure, C19H15N3, CAS 866542-98-5
4-(5-Phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-phenylamine
CAS 866542-98-5C19H15N3
2-Methoxy-4-[3-(2-methoxy-phenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]phenol chemical structure, C21H18N2O3, CAS 875638-65-6
2-Methoxy-4-[3-(2-methoxy-phenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]phenol
CAS 875638-65-6C21H18N2O3
4-(3-(4-Hydroxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)-2-methoxyphenol chemical structure, C20H16N2O3, CAS 875638-52-1
4-(3-(4-Hydroxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)-2-methoxyphenol
CAS 875638-52-1C20H16N2O3
2-Amino-5-[3-(2-methoxy-phenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethyl-benzamide chemical structure, C23H22N4O2, CAS 875638-86-1
2-Amino-5-[3-(2-methoxy-phenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethyl-benzamide
CAS 875638-86-1C23H22N4O2
3-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylbenzamide chemical structure, C23H21N3O2, CAS 875634-45-0
3-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylbenzamide
CAS 875634-45-0C23H21N3O2
4-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]benzenamine chemical structure, C20H17N3O, CAS 1070979-44-0
4-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]benzenamine
CAS 1070979-44-0C20H17N3O
3-(2-Methoxyphenyl)-5-phenyl-1H-pyrrolo[2,3-b]pyridine chemical structure, C20H16N2O, CAS 757980-78-2
3-(2-Methoxyphenyl)-5-phenyl-1H-pyrrolo[2,3-b]pyridine
CAS 757980-78-2C20H16N2O
4-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]phenol chemical structure, C20H16N2O2, CAS 875634-06-3
4-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]phenol
CAS 875634-06-3C20H16N2O2
2-(2-Methylpropyl)-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid chemical structure, C24H22N2O2, CAS 890842-34-9
2-(2-Methylpropyl)-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid
CAS 890842-34-9C24H22N2O2
2-Ethyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid chemical structure, C22H18N2O2, CAS 890842-25-8
2-Ethyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid
CAS 890842-25-8C22H18N2O2
2-Methyl-2-(4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)propanoic acid chemical structure, C23H20N2O2, CAS 890842-69-0
2-Methyl-2-(4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)propanoic acid
CAS 890842-69-0C23H20N2O2
2-Fluoro-4-[3-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]phenol chemical structure, C20H15FN2O2, CAS 875638-69-0
2-Fluoro-4-[3-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]phenol
CAS 875638-69-0C20H15FN2O2
3-[3-(2-Methoxy-phenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-phenol chemical structure, C20H16N2O2, CAS 875638-59-8
3-[3-(2-Methoxy-phenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-phenol
CAS 875638-59-8C20H16N2O2
N,N-Dimethyl-3-(3-phenyl-1H-pyrrolo[2,3-b]pyridin-5-yl)benzenamine chemical structure, C21H19N3, CAS 875638-49-6
N,N-Dimethyl-3-(3-phenyl-1H-pyrrolo[2,3-b]pyridin-5-yl)benzenamine
CAS 875638-49-6C21H19N3
4-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]benzamide chemical structure, C21H17N3O2, CAS 875638-61-2
4-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]benzamide
CAS 875638-61-2C21H17N3O2
3-(3-Phenyl-1H-pyrrolo[2,3-b]pyridin-5-yl)phenol chemical structure, C19H14N2O, CAS 875637-14-2
3-(3-Phenyl-1H-pyrrolo[2,3-b]pyridin-5-yl)phenol
CAS 875637-14-2C19H14N2O
5-(3,4-Dimethoxyphenyl)-3-(4-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridine chemical structure, C22H20N2O3, CAS 875638-56-5
5-(3,4-Dimethoxyphenyl)-3-(4-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridine
CAS 875638-56-5C22H20N2O3
2-Methoxy-4-[3-(4-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]phenol chemical structure, C21H18N2O3, CAS 875638-66-7
2-Methoxy-4-[3-(4-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]phenol
CAS 875638-66-7C21H18N2O3
5-(3,4-Dimethoxyphenyl)-3-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridine chemical structure, C22H20N2O3, CAS 875638-57-6
5-(3,4-Dimethoxyphenyl)-3-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridine
CAS 875638-57-6C22H20N2O3
5-(3,4-Dichlorophenyl)-3-phenyl-1H-pyrrolo[2,3-b]pyridine chemical structure, C19H12Cl2N2, CAS 875638-48-5
5-(3,4-Dichlorophenyl)-3-phenyl-1H-pyrrolo[2,3-b]pyridine
CAS 875638-48-5C19H12Cl2N2
5-(3,4-Dimethoxyphenyl)-3-phenyl-1H-pyrrolo[2,3-b]pyridine chemical structure, C21H18N2O2, CAS 875638-40-7
5-(3,4-Dimethoxyphenyl)-3-phenyl-1H-pyrrolo[2,3-b]pyridine
CAS 875638-40-7C21H18N2O2
3-(2-Methoxyphenyl)-5-(4-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridine chemical structure, C21H18N2O2, CAS 875638-64-5
3-(2-Methoxyphenyl)-5-(4-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridine
CAS 875638-64-5C21H18N2O2