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Murcko scaffold

3,6-Diphenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine scaffold

73 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
73
With full pages
8
Scaffold SMILES

c1ccc(C2=Nn3c(nnc3-c3ccccc3)SC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3,6-Diphenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine page
Murcko scaffold c1ccc(C2=Nn3c(nnc3-c3ccccc3)SC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 73 chemicals

6-Phenyl-3-(3,4,5-trimethoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C19H18N4O3S, CAS 67572-55-8
6-Phenyl-3-(3,4,5-trimethoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
CAS 67572-55-8C19H18N4O3S
6-(2,5-Dimethoxyphenyl)-3-[3-(1-methylethoxy)phenyl]-7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C21H22N4O3S, CAS 842971-85-1
6-(2,5-Dimethoxyphenyl)-3-[3-(1-methylethoxy)phenyl]-7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazine
CAS 842971-85-1C21H22N4O3S
3-(3-Methylphenyl)-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C17H14N4S, CAS 577763-02-1
3-(3-Methylphenyl)-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
CAS 577763-02-1C17H14N4S
6-(4-Ethoxyphenyl)-3-(2-methoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C19H18N4O2S, CAS 578723-96-3
6-(4-Ethoxyphenyl)-3-(2-methoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
CAS 578723-96-3C19H18N4O2S
6-(4-Nitrophenyl)-3-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C16H11N5O2S, CAS 68469-07-8
6-(4-Nitrophenyl)-3-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
CAS 68469-07-8C16H11N5O2S
6-(4-Methoxyphenyl)-3-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C17H14N4OS, CAS 85106-28-1
6-(4-Methoxyphenyl)-3-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
CAS 85106-28-1C17H14N4OS
3-(4-Chlorophenyl)-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C16H11ClN4S, CAS 68469-09-0
3-(4-Chlorophenyl)-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
CAS 68469-09-0C16H11ClN4S
3,6-Diphenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C16H12N4S, CAS 79074-65-0
3,6-Diphenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
CAS 79074-65-0C16H12N4S
3-(3-Chlorophenyl)-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C16H11ClN4S, CAS 117320-85-1
3-(3-Chlorophenyl)-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
CAS 117320-85-1C16H11ClN4S
6-(4-Fluorophenyl)-3-(4-methoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C17H13FN4OS, CAS 688792-17-8
6-(4-Fluorophenyl)-3-(4-methoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
CAS 688792-17-8C17H13FN4OS
6-(4-Fluorophenyl)-3-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C16H11FN4S, CAS 840517-90-0
6-(4-Fluorophenyl)-3-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
CAS 840517-90-0C16H11FN4S
3-(4-Methoxyphenyl)-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C17H14N4OS, CAS 85106-42-9
3-(4-Methoxyphenyl)-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
CAS 85106-42-9C17H14N4OS
6-(4-Fluorophenyl)-3-(2-methoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C17H13FN4OS, CAS 843618-60-0
6-(4-Fluorophenyl)-3-(2-methoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
CAS 843618-60-0C17H13FN4OS
3-(4-Fluorophenyl)-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C16H11FN4S, CAS 257614-67-8
3-(4-Fluorophenyl)-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
CAS 257614-67-8C16H11FN4S
6-(4-Chlorophenyl)-3-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C16H11ClN4S, CAS 68469-05-6
6-(4-Chlorophenyl)-3-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
CAS 68469-05-6C16H11ClN4S
6-(4-Bromophenyl)-3-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C16H11BrN4S, CAS 68469-06-7
6-(4-Bromophenyl)-3-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
CAS 68469-06-7C16H11BrN4S
6-(4-Bromophenyl)-3-(4-methylphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C17H13BrN4S, CAS 85106-39-4
6-(4-Bromophenyl)-3-(4-methylphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
CAS 85106-39-4C17H13BrN4S
6-(3-Nitrophenyl)-3-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C16H11N5O2S, CAS 68469-08-9
6-(3-Nitrophenyl)-3-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
CAS 68469-08-9C16H11N5O2S
6-(2,4-Dichlorophenyl)-3-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C16H10Cl2N4S, CAS 477846-69-8
6-(2,4-Dichlorophenyl)-3-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
CAS 477846-69-8C16H10Cl2N4S
6-(2,4-Dichlorophenyl)-3-(4-methoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C17H12Cl2N4OS, CAS 382596-01-2
6-(2,4-Dichlorophenyl)-3-(4-methoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
CAS 382596-01-2C17H12Cl2N4OS
6-(4-Methylphenyl)-3-[4-(trifluoromethyl)phenyl]-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C18H13F3N4S, CAS 477857-06-0
6-(4-Methylphenyl)-3-[4-(trifluoromethyl)phenyl]-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
CAS 477857-06-0C18H13F3N4S
7H-1,2,4-Triazolo(3,4-b)(1,3,4)thiadiazine-7-acetic acid, 6-phenyl-3-(3,4,5-trimethoxyphenyl)- chemical structure, C21H20N4O5S, CAS 126598-10-5
7H-1,2,4-Triazolo(3,4-b)(1,3,4)thiadiazine-7-acetic acid, 6-phenyl-3-(3,4,5-trimethoxyphenyl)-
CAS 126598-10-5C21H20N4O5S
7H-1,2,4-Triazolo(3,4-b)(1,3,4)thiadiazine-7-acetic acid, 6-(4-fluorophenyl)-3-(3,4,5-trimethoxyphenyl)- chemical structure, C21H19FN4O5S, CAS 126598-11-6
7H-1,2,4-Triazolo(3,4-b)(1,3,4)thiadiazine-7-acetic acid, 6-(4-fluorophenyl)-3-(3,4,5-trimethoxyphenyl)-
CAS 126598-11-6C21H19FN4O5S
7H-1,2,4-Triazolo(3,4-b)(1,3,4)thiadiazine-7-acetic acid, 6-(4-chlorophenyl)-3-(3,4,5-trimethoxyphenyl)- chemical structure, C21H19ClN4O5S, CAS 126598-12-7
7H-1,2,4-Triazolo(3,4-b)(1,3,4)thiadiazine-7-acetic acid, 6-(4-chlorophenyl)-3-(3,4,5-trimethoxyphenyl)-
CAS 126598-12-7C21H19ClN4O5S