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Murcko scaffold

4-Piperazin-1-ylquinazoline scaffold

77 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
77
With full pages
9
Scaffold SMILES

c1ccc2c(N3CCNCC3)ncnc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Piperazin-1-ylquinazoline page
Murcko scaffold c1ccc2c(N3CCNCC3)ncnc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 77 chemicals

Piquizil chemical structure, C19H26N4O4, CAS 21560-58-7
Piquizil
CAS 21560-58-7C19H26N4O4
Hoquizil chemical structure, C19H26N4O5, CAS 21560-59-8
Hoquizil
CAS 21560-59-8C19H26N4O5
Hoquizil hydrochloride chemical structure, C19H27ClN4O5, CAS 23256-28-2
Hoquizil hydrochloride
CAS 23256-28-2C19H27ClN4O5
Piquizil hydrochloride chemical structure, C19H27ClN4O4, CAS 23256-26-0
Piquizil hydrochloride
CAS 23256-26-0C19H27ClN4O4
6-Bromo-4-(4-methylpiperazin-1-yl)quinazoline chemical structure, C13H15BrN4, CAS 307538-54-1
6-Bromo-4-(4-methylpiperazin-1-yl)quinazoline
CAS 307538-54-1C13H15BrN4
6-Bromo-4-(4-ethylpiperazin-1-yl)quinazoline chemical structure, C14H17BrN4, CAS 307538-58-5
6-Bromo-4-(4-ethylpiperazin-1-yl)quinazoline
CAS 307538-58-5C14H17BrN4
Ethyl 4-(quinazolin-4-yl)piperazine-1-carboxylate chemical structure, C15H18N4O2, CAS 1223227-46-0
Ethyl 4-(quinazolin-4-yl)piperazine-1-carboxylate
CAS 1223227-46-0C15H18N4O2
4-(4-Methylpiperazino)-2-(methylsulfanyl)quinazoline chemical structure, C14H18N4S, CAS 866019-90-1
4-(4-Methylpiperazino)-2-(methylsulfanyl)quinazoline
CAS 866019-90-1C14H18N4S
2-Methyl-4-piperazin-1-yl-quinazoline chemical structure, C13H16N4, CAS 59637-47-7
2-Methyl-4-piperazin-1-yl-quinazoline
CAS 59637-47-7C13H16N4
4-Piperazin-1-ylquinazoline chemical structure, C12H14N4, CAS 59215-41-7
4-Piperazin-1-ylquinazoline
CAS 59215-41-7C12H14N4
6,7-Dimethoxy-4-piperazin-1-yl-quinazoline chemical structure, C14H18N4O2, CAS 21584-72-5
6,7-Dimethoxy-4-piperazin-1-yl-quinazoline
CAS 21584-72-5C14H18N4O2
6,7-Dimethoxy-4-(4-methylpiperazin-1-yl)quinazoline chemical structure, C15H20N4O2, CAS 21584-74-7
6,7-Dimethoxy-4-(4-methylpiperazin-1-yl)quinazoline
CAS 21584-74-7C15H20N4O2
6-Bromo-4-(piperazin-1-yl)quinazoline chemical structure, C12H13BrN4, CAS 205259-86-5
6-Bromo-4-(piperazin-1-yl)quinazoline
CAS 205259-86-5C12H13BrN4
4-(Piperazin-1-yl)-2-(trifluoromethyl)quinazoline chemical structure, C13H13F3N4, CAS 401567-99-5
4-(Piperazin-1-yl)-2-(trifluoromethyl)quinazoline
CAS 401567-99-5C13H13F3N4
1-[4-(6,7-Dimethoxyquinazolin-4-yl)piperazin-1-yl]ethanone chemical structure, C16H20N4O3, CAS 21584-89-4
1-[4-(6,7-Dimethoxyquinazolin-4-yl)piperazin-1-yl]ethanone
CAS 21584-89-4C16H20N4O3
6,7-Dimethoxy-2-methyl-4-(piperazin-1-yl)quinazoline chemical structure, C15H20N4O2, CAS 205260-07-7
6,7-Dimethoxy-2-methyl-4-(piperazin-1-yl)quinazoline
CAS 205260-07-7C15H20N4O2
4-(4-Methylpiperazin-1-yl)quinazolin-6-amine chemical structure, C13H17N5, CAS 338797-07-2
4-(4-Methylpiperazin-1-yl)quinazolin-6-amine
CAS 338797-07-2C13H17N5
6-Bromo-4-(piperazin-1-yl)quinazoline hydrochloride chemical structure, C12H14BrClN4, CAS 1177356-94-3
6-Bromo-4-(piperazin-1-yl)quinazoline hydrochloride
CAS 1177356-94-3C12H14BrClN4
7-Quinazolinecarboxylic acid, 4-(1-piperazinyl)-, hydrochloride (1:1) chemical structure, C13H15ClN4O2, CAS 1177333-59-3
7-Quinazolinecarboxylic acid, 4-(1-piperazinyl)-, hydrochloride (1:1)
CAS 1177333-59-3C13H15ClN4O2
2-[4-(6,7-Dimethoxyquinazolin-4-yl)piperazin-1-yl]ethan-1-ol chemical structure, C16H22N4O3, CAS 21584-78-1
2-[4-(6,7-Dimethoxyquinazolin-4-yl)piperazin-1-yl]ethan-1-ol
CAS 21584-78-1C16H22N4O3
4-(4-Methylpiperazin-1-yl)quinazoline chemical structure, C13H16N4, CAS 26731-83-9
4-(4-Methylpiperazin-1-yl)quinazoline
CAS 26731-83-9C13H16N4
2-Chloro-4-(4-methylpiperazin-1-yl)quinazoline chemical structure, C13H15ClN4, CAS 39216-68-7
2-Chloro-4-(4-methylpiperazin-1-yl)quinazoline
CAS 39216-68-7C13H15ClN4
6,8-Dichloro-4-piperazin-1-YL-quinazoline chemical structure, C12H12Cl2N4, CAS 72700-41-5
6,8-Dichloro-4-piperazin-1-YL-quinazoline
CAS 72700-41-5C12H12Cl2N4
tert-Butyl 4-(6-bromoquinazolin-4-yl)piperazine-1-carboxylate chemical structure, C17H21BrN4O2, CAS 474710-31-1
tert-Butyl 4-(6-bromoquinazolin-4-yl)piperazine-1-carboxylate
CAS 474710-31-1C17H21BrN4O2