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Murcko scaffold

Ring system with 3 rings and 15 atoms

80 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
80
With full pages
9
Scaffold SMILES

O=c1[nH]cnc2c1ccn2C1CCCO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]cnc2c1ccn2C1CCCO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 80 of 80 chemicals

7-Deaza-2'-deoxyinosine chemical structure, C11H13N3O4
7-Deaza-2'-deoxyinosine
C11H13N3O4
((2R,3S,5R)-5-(2-Amino-5-iodo-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate chemical structure, C11H16IN4O13P3, CAS 244109-12-4
((2R,3S,5R)-5-(2-Amino-5-iodo-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate
CAS 244109-12-4C11H16IN4O13P3
2-Amino-7-(2-amino-2-deoxy-|A-D-arabinofuranosyl)-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid methyl ester chemical structure, C13H17N5O6, CAS 84873-16-5
2-Amino-7-(2-amino-2-deoxy-|A-D-arabinofuranosyl)-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid methyl ester
CAS 84873-16-5C13H17N5O6
7-Deaza-7-(propynyl)-2'-deoxyguanosine chemical structure, C14H16N4O4, CAS 182743-56-2
7-Deaza-7-(propynyl)-2'-deoxyguanosine
CAS 182743-56-2C14H16N4O4
7-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-3H-pyrrolo[2,3-d]pyrimidin-4-one chemical structure, C11H12IN3O4, CAS 220870-02-0
7-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-3H-pyrrolo[2,3-d]pyrimidin-4-one
CAS 220870-02-0C11H12IN3O4
5-Chloro-7-(2-deoxy-|A-D-erythro-pentofuranosyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one chemical structure, C11H12ClN3O4, CAS 220870-00-8
5-Chloro-7-(2-deoxy-|A-D-erythro-pentofuranosyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
CAS 220870-00-8C11H12ClN3O4
7-TFA-ap-7-Deaza-dG chemical structure, C16H16F3N5O5, CAS 666847-77-4
7-TFA-ap-7-Deaza-dG
CAS 666847-77-4C16H16F3N5O5
2-Amino-7-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile chemical structure, C12H13N5O4, CAS 199859-58-0
2-Amino-7-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
CAS 199859-58-0C12H13N5O4
4H-Pyrrolo[2,3-d]pyrimidin-4-one, 7-(2-deoxy-|A-D-erythro-pentofuranosyl)-1,7-dihydro- chemical structure, C11H13N3O4, CAS 97224-58-3
4H-Pyrrolo[2,3-d]pyrimidin-4-one, 7-(2-deoxy-|A-D-erythro-pentofuranosyl)-1,7-dihydro-
CAS 97224-58-3C11H13N3O4
N2-(dimethylaminomethylidene)-7-deaza-2'-deoxyguanosine chemical structure, C14H19N5O4
N2-(dimethylaminomethylidene)-7-deaza-2'-deoxyguanosine
C14H19N5O4
N'-[7-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-2-yl]-N,N-dimethylmethanimidamide chemical structure, C14H19N5O4, CAS 111902-68-2
N'-[7-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-2-yl]-N,N-dimethylmethanimidamide
CAS 111902-68-2C14H19N5O4
7-Cyano-7-deaza-2'-deoxy guanosine chemical structure, C12H13N5O4
7-Cyano-7-deaza-2'-deoxy guanosine
C12H13N5O4
2-Amino-7-[2-deoxy-4-C-(fluoromethyl)-|A-Derythro-pentofuranosyl]-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one chemical structure, C12H15FN4O4, CAS 2230620-16-1
2-Amino-7-[2-deoxy-4-C-(fluoromethyl)-|A-Derythro-pentofuranosyl]-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
CAS 2230620-16-1C12H15FN4O4
N'-[7-[4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-2-yl]-N,N-dimethylmethanimidamide chemical structure, C14H19N5O4
N'-[7-[4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-2-yl]-N,N-dimethylmethanimidamide
C14H19N5O4
7-[(2S,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H,4H,7H-pyrrolo[2,3-d]pyrimidin-4-one chemical structure, C11H13N3O4
7-[(2S,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H,4H,7H-pyrrolo[2,3-d]pyrimidin-4-one
C11H13N3O4
7-Deaza-7-propargylamino-3'-azidomethyl-dGTP chemical structure, C15H21N8O13P3, CAS 666847-81-0
7-Deaza-7-propargylamino-3'-azidomethyl-dGTP
CAS 666847-81-0C15H21N8O13P3
7-Deaza-7-propargylamino-dGTP chemical structure, C14H20N5O13P3, CAS 587848-73-5
7-Deaza-7-propargylamino-dGTP
CAS 587848-73-5C14H20N5O13P3
N2-(Dimethylaminomethylidene)-7-deaza-2'-deoxyguanosine chemical structure, C14H19N5O4
N2-(Dimethylaminomethylidene)-7-deaza-2'-deoxyguanosine
C14H19N5O4
(3S,4R,5R)-5-(2-Amino-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-7(4H)-yl)-4-hydroxytetrahydrofuran-3-yl dihydrogen phosphate chemical structure, C10H13N4O7P, CAS 2305661-81-6
(3S,4R,5R)-5-(2-Amino-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-7(4H)-yl)-4-hydroxytetrahydrofuran-3-yl dihydrogen phosphate
CAS 2305661-81-6C10H13N4O7P
(3S,4R,5R)-5-(2-Amino-5-iodo-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-7(4H)-yl)-4-hydroxytetrahydrofuran-3-yl dihydrogen phosphate chemical structure, C10H12IN4O7P, CAS 2305661-80-5
(3S,4R,5R)-5-(2-Amino-5-iodo-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-7(4H)-yl)-4-hydroxytetrahydrofuran-3-yl dihydrogen phosphate
CAS 2305661-80-5C10H12IN4O7P
(3S,4R,5R)-5-(2-Amino-5-iodo-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-7(4H)-yl)-4-hydroxytetrahydrofuran-3-yl tetrahydrogen triphosphate chemical structure, C10H14IN4O13P3, CAS 2305661-86-1
(3S,4R,5R)-5-(2-Amino-5-iodo-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-7(4H)-yl)-4-hydroxytetrahydrofuran-3-yl tetrahydrogen triphosphate
CAS 2305661-86-1C10H14IN4O13P3
(3S,4R,5R)-5-(2-Amino-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-7(4H)-yl)-4-hydroxytetrahydrofuran-3-yl tetrahydrogen triphosphate chemical structure, C10H15N4O13P3, CAS 2305661-87-2
(3S,4R,5R)-5-(2-Amino-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-7(4H)-yl)-4-hydroxytetrahydrofuran-3-yl tetrahydrogen triphosphate
CAS 2305661-87-2C10H15N4O13P3
7-Deaza-2'-deoxyguanosine-5'-triphisphate chemical structure, C11H13N4Na4O13P3, CAS 2579172-47-5
7-Deaza-2'-deoxyguanosine-5'-triphisphate
CAS 2579172-47-5C11H13N4Na4O13P3
((2R,3S,5R)-5-(2-Amino-5-iodo-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3-hydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate chemical structure, C11H14IN4O7P, CAS 1190922-17-8
((2R,3S,5R)-5-(2-Amino-5-iodo-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3-hydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate
CAS 1190922-17-8C11H14IN4O7P